2020
The alternative complement pathway in ANCA-associated vasculitis: further evidence and a meta-analysis
Moiseev S, Lee J, Zykova A, Bulanov N, Novikov P, Gitel E, Bulanova M, Safonova E, Shin J, Kronbichler A, Jayne D. The alternative complement pathway in ANCA-associated vasculitis: further evidence and a meta-analysis. Clinical & Experimental Immunology 2020, 202: 394-402. PMID: 32691878, PMCID: PMC7670131, DOI: 10.1111/cei.13498.Peer-Reviewed Original ResearchConceptsANCA-associated vasculitis patientsANCA-associated vasculitisActive ANCA-associated vasculitisMembrane attack complexMeta-analysisComplement levelsPathogenesis of ANCA-associated vasculitisAchievement of remissionRandom-effects modelFactor B levelsRelapsing granulomatosisMicroscopic polyangiitisANCA specificityAlternative complement pathwayAssociated with reductionsHealthy volunteersClinical evidenceBorderline significanceHealthy controlsFactor BRemissionPatientsC5b-9Properdin levelsB levels
2018
AB0538 Increased body mass index may not be a risk factor for the development of lupus nephritis
Chock Y, Danve A, School of Medicine O, Petri M, Fu W. AB0538 Increased body mass index may not be a risk factor for the development of lupus nephritis. Annals Of The Rheumatic Diseases 2018, 77: 1425-1426. DOI: 10.1136/annrheumdis-2018-eular.4524.Peer-Reviewed Original ResearchSystemic lupus erythematosusBody mass indexChronic kidney diseaseLow disease activityLupus nephritisSLE patientsDisease activityComplement levelsMass indexAvailable body mass indexBiopsy-proven lupus nephritisLow-grade inflammatory stateElevated body mass indexRetrospective cross-sectional studyFirst BMI measurementRisk of nephritisCategorical variablesHigher leptin levelsCross-sectional studyHigher complement levelsChi-square testLupus CohortCohort entryObese patientsACR criteria
2008
Delayed intravascular haemolysis following multiple asymptomatic ABO‐incompatible red blood cell transfusions in a patient with hepatic failure
Tormey CA, Stack G. Delayed intravascular haemolysis following multiple asymptomatic ABO‐incompatible red blood cell transfusions in a patient with hepatic failure. Vox Sanguinis 2008, 95: 232-235. PMID: 19121188, DOI: 10.1111/j.1423-0410.2008.01085.x.Peer-Reviewed Original ResearchConceptsABO-incompatible red blood cell (RBC) transfusionsRed blood cell transfusionBlood cell transfusionFresh frozen plasmaCell transfusionHepatic failureDelayed Haemolytic Transfusion ReactionAnamnestic antibody responseLow complement levelsHaemolytic transfusion reactionsOnset of haemolysisFirst transfusionRBC transfusionComplement levelsIncompatible transfusionsAntibody responseAntibody titresHepatic diseaseTransfusion reactionsIntravascular haemolysisTransfusionPatientsRBC unitsB RBCsHaemolysis
1985
Determination of 16 alpha‐hydroxyestrone by radioimmunoassay in systemic lupus erythematosus
Lahita R, Bucala R, Bradlow H, Fishman J. Determination of 16 alpha‐hydroxyestrone by radioimmunoassay in systemic lupus erythematosus. Arthritis & Rheumatism 1985, 28: 1122-1127. PMID: 4052123, DOI: 10.1002/art.1780281007.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusActive diseaseLupus erythematosusInactive systemic lupus erythematosusVariety of seraInactive diseaseSLE patientsAntibody levelsComplement levelsRheumatic diseasesLaboratory criteriaAlpha-hydroxyestroneHormone levelsHealthy volunteersNormal controlsPatientsEstrogenic metabolitesNormal levelsDiseaseErythematosusSignificant increaseRadioimmunoassayPoor correlationMetabolitesHigh levels
1975
Diffuse glomerulonephritis in rabbits with Streptococcus viridans endocarditis.
Arnold S, Valone J, Askenase P, Kashgarian M, Freedman L. Diffuse glomerulonephritis in rabbits with Streptococcus viridans endocarditis. Laboratory Investigation 1975, 32: 681-9. PMID: 125360.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, BacterialComplement C3Disease Models, AnimalEndocarditis, BacterialFluorescent Antibody TechniqueGlomerulonephritisHistological TechniquesImmune Complex DiseasesImmunizationImmunoglobulin GKidneyMaleMicroscopy, ElectronMicroscopy, FluorescenceRabbitsRheumatoid FactorSplenomegalyStreptococcal InfectionsConceptsInfective endocarditisDiffuse glomerulonephritisSubendothelial electron-dense depositsStreptococcus viridans endocarditisDeposition of IgGDiffuse proliferative glomerulonephritisSerum complement levelsAcute diffuse proliferative glomerulonephritisPositive blood culturesElectron microscopic findingsElectron-dense depositsComplement levelsGlomerular changesValvular vegetationsRheumatoid factorLeukocytic infiltrationMesangial proliferationProliferative glomerulonephritisBlood culturesImmune mechanismsCapillary occlusionMorphologic findingsIntravenous administrationMicroscopic findingsEndocarditis
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