2023
Epidemiological and clinical features, therapeutic strategies and outcomes in patients with hyperhaemolysis: A systematic review
Jacobs J, Stephens L, Allen E, Binns T, Booth G, Hendrickson J, Karafin M, Tormey C, Woo J, Adkins B. Epidemiological and clinical features, therapeutic strategies and outcomes in patients with hyperhaemolysis: A systematic review. British Journal Of Haematology 2023, 201: 1025-1032. PMID: 37074146, DOI: 10.1111/bjh.18825.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSickle cell diseaseHyperhaemolysis syndromeAnti-globulin testRed blood cellsSupportive transfusionsIndirect anti-globulin testDirect anti-globulin testIntravenous immune globulinHaemolytic transfusion reactionsImmune globulinMedian hemoglobinClinical featuresCommon therapyUnderlying pathophysiologyTransfusion reactionsCell diseaseSevere formTherapeutic strategiesPatientsSystematic reviewBlood cellsTransfusionHyperhaemolysisDaysCorticosteroids
2019
Recipient factors influencing red blood cell alloimmunization
Hendrickson J. Recipient factors influencing red blood cell alloimmunization. ISBT Science Series 2019, 15: 194-200. DOI: 10.1111/voxs.12485.Peer-Reviewed Original ResearchSickle cell diseaseRBC alloantibodiesMyelodysplastic syndromeRed blood cell alloimmunizationRed blood cell alloantibodiesRBC alloantibody formationReductionist murine modelHaemolytic transfusion reactionsType of inflammationHigh prevalence ratesForms of autoimmunityDetectable alloantibodiesRBC alloimmunizationTransfusion avoidanceTransfusion burdenAlloantibody formationAntigen matchingRecipient factorsAntibody screenPatient populationHaemolytic diseaseRBC exposureRisk factorsTransfusion reactionsMurine model
2018
Delayed haemolytic and serologic transfusion reactions
Siddon AJ, Kenney BC, Hendrickson JE, Tormey CA. Delayed haemolytic and serologic transfusion reactions. Current Opinion In Hematology 2018, 25: 459-467. PMID: 30124474, DOI: 10.1097/moh.0000000000000462.Peer-Reviewed Original ResearchConceptsSickle cell diseaseAdverse eventsTransfusion reactionsTransfusion-associated adverse eventsHaemolytic transfusion reactionsSerologic transfusion reactionsGeneral patient groupNovel immunosuppressive agentPractical preventive strategiesEvidence-based approachImmune dysregulationImmunosuppressive agentsPatient groupTransfusion recipientsRisk factorsBasic epidemiologyCell diseasePreventive strategiesRed blood cell deathAntibody detectionDHTRHaemolytic reactionsMultitude of reportsCell deathDHTRs
2010
Use of mouse models to study the mechanisms and consequences of RBC clearance
Hod E, Arinsburg S, Francis R, Hendrickson J, Zimring J, Spitalnik S. Use of mouse models to study the mechanisms and consequences of RBC clearance. Vox Sanguinis 2010, 99: 99-111. PMID: 20345515, PMCID: PMC3580149, DOI: 10.1111/j.1423-0410.2010.01327.x.Peer-Reviewed Original ResearchConceptsMouse modelRBC clearanceImmune globulin therapyAutoimmune haemolytic anaemiaHaemolytic transfusion reactionsGlobulin therapyRBC transfusionTransfusion reactionsHaemolytic anaemiaAnimal modelsTractable animal modelTransfusion medicineCell clearanceClearancePathophysiologyHuman disordersUnanswered questionsTransfusionComplicationsAnemiaImmunomodulationTherapyMiceAntibodies
2008
Delayed intravascular haemolysis following multiple asymptomatic ABO‐incompatible red blood cell transfusions in a patient with hepatic failure
Tormey CA, Stack G. Delayed intravascular haemolysis following multiple asymptomatic ABO‐incompatible red blood cell transfusions in a patient with hepatic failure. Vox Sanguinis 2008, 95: 232-235. PMID: 19121188, DOI: 10.1111/j.1423-0410.2008.01085.x.Peer-Reviewed Original ResearchConceptsABO-incompatible red blood cell (RBC) transfusionsRed blood cell transfusionBlood cell transfusionFresh frozen plasmaCell transfusionHepatic failureDelayed Haemolytic Transfusion ReactionAnamnestic antibody responseLow complement levelsHaemolytic transfusion reactionsOnset of haemolysisFirst transfusionRBC transfusionComplement levelsIncompatible transfusionsAntibody responseAntibody titresHepatic diseaseTransfusion reactionsIntravascular haemolysisTransfusionPatientsRBC unitsB RBCsHaemolysis
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