2025
An all-oral regimen of decitabine-cedazuridine (DEC-C) plus venetoclax (VEN) in patients (pts) with newly diagnosed acute myeloid leukemia (AML) ineligible for intensive induction chemotherapy: Results from a phase 2 cohort of 101 pts.
Zeidan A, Griffiths E, Dinardo C, Mannis G, Montesinos P, Arnan M, Savona M, Odenike O, McCloskey J, Amin H, Fathi A, Bernal del Castillo T, Rodriguez-Macias G, Liesveld J, Im A, Oganesian A, Xu Q, Dijkstra M, Keer H, Roboz G. An all-oral regimen of decitabine-cedazuridine (DEC-C) plus venetoclax (VEN) in patients (pts) with newly diagnosed acute myeloid leukemia (AML) ineligible for intensive induction chemotherapy: Results from a phase 2 cohort of 101 pts. Journal Of Clinical Oncology 2025, 43: 6504-6504. DOI: 10.1200/jco.2025.43.16_suppl.6504.Peer-Reviewed Original ResearchAcute myeloid leukemiaAll-oral regimenInduction chemotherapyEuropean LeukemiaNetCR rateMedian time to CRTreatment-emergent adverse eventsBCL-2 inhibitor venetoclaxDiagnosed AMLDiagnosed acute myeloid leukemiaMedian CR durationPhase 2 partAll-oral regimensIntensive induction chemotherapyPhase 1/2 trialBone marrow examinationMedian Follow-UpTime to CRConfidence intervalsDrug-drug interactionsPhase 2 cohortIntravenous decitabineMedian OSCR durationFebrile neutropenia
2020
Largest Cohort Study of Gaucher Disease Type 3 from a Single Center in Egypt Spanning Two Decades
El-Beshlawy A, Eid K, AbdelSalam A, Mohamed F, Selim Y, Gebril N, Fateen E, Mistry P. Largest Cohort Study of Gaucher Disease Type 3 from a Single Center in Egypt Spanning Two Decades. Blood 2020, 136: 21-22. DOI: 10.1182/blood-2020-141776.Peer-Reviewed Original ResearchEnzyme replacement therapyOverall survivalPediatric hematology clinicGaucher diseaseHepatopulmonary syndromeCohort studyNeurological findingsGBA mutationsHigh-dose enzyme replacement therapyLarge single-centre cohort studySingle-center cohort studyType 1 Gaucher diseaseCommon neurological findingsGaucher cell infiltrationCenter cohort studySingle-center cohortBaseline disease severityBone marrow examinationDate of diagnosisGaucher disease type 3Kaplan-Meier analysisLong-term outcomesProgressive neurological diseaseEarly-onset diseaseLarge cohort study
2019
Monoclonal Gammopathy of Renal Significance Triggered by Viral E Hepatitis
Agrawal P, Kumar V, Kumar A, Sachdeva M, Malhotra P, Nada R. Monoclonal Gammopathy of Renal Significance Triggered by Viral E Hepatitis. Indian Journal Of Nephrology 2019, 29: 50-52. PMID: 30814794, PMCID: PMC6375020, DOI: 10.4103/ijn.ijn_417_17.Peer-Reviewed Original ResearchMonoclonal gammopathy of renal significanceLight chain cast nephropathyMonoclonal gammopathyRenal significanceCast nephropathyDrug-induced interstitial nephritisAcute hepatitis E infectionBone marrow examinationAcute hepatitis EHepatitis E infectionTubular epithelial cellsProportion of casesMGRS lesionsMarrow examinationClinical suspicionProximal tubulopathyGiant cell reactionElevated creatinineKappa restrictionSerum calciumKidney biopsyB2-microglobulinRenal injuryPlasma cellsInterstitial nephritis
2017
Day 14 bone marrow examination in the management of acute myeloid leukemia
Terry CM, Shallis RM, Estey E, Lim SH. Day 14 bone marrow examination in the management of acute myeloid leukemia. American Journal Of Hematology 2017, 92: 1079-1084. PMID: 28612456, DOI: 10.1002/ajh.24818.Peer-Reviewed Original ResearchConceptsDay 14 bone marrowBlast cell countNational Comprehensive Cancer NetworkBone marrow examinationInduction therapyBone marrowCell countMarrow examinationSecond induction therapyLonger hospital stayTreatment-related mortalityComprehensive Cancer NetworkManagement of patientsBone marrow evaluationAcute myeloid leukemiaFurther chemotherapyComplete remissionHospital stayIntravenous antimicrobialsMarrow evaluationClinical trialsBlood productsMyeloid leukemiaHigh riskDay 28
2012
Composite Peripheral T-cell Lymphoma Not Otherwise Specified, and B-cell Small Lymphocytic Lymphoma Presenting With Hemophagocytic Lymphohistiocytosis
Alomari A, Hui P, Xu M. Composite Peripheral T-cell Lymphoma Not Otherwise Specified, and B-cell Small Lymphocytic Lymphoma Presenting With Hemophagocytic Lymphohistiocytosis. International Journal Of Surgical Pathology 2012, 21: 303-308. PMID: 23129836, DOI: 10.1177/1066896912464047.Peer-Reviewed Original ResearchConceptsPeripheral T-cell lymphomaT-cell lymphomaHemophagocytic lymphohistiocytosisB-cell lymphomaB-cell small lymphocytic lymphoma/chronic lymphocytic leukemiaSmall lymphocytic lymphoma/chronic lymphocytic leukemiaDevelopment of HLHPatient's B-cell lymphomaSymptoms of HLHComposite B-cellPara-aortic lymphadenopathyBone marrow examinationGood initial responseHigh-grade lymphomaChronic lymphocytic leukemiaLymphoma PresentingMarrow examinationPara-aorticImmune dysregulationLymph nodesFemale patientsDifferent regimensHepatocellular necrosisComposite lymphomaLymphocytic leukemia
2011
Recombinant macrophage targeted enzyme replacement therapy for Gaucher disease in India
Nagral A, Mewawalla P, Jagadeesh S, Kabra M, Phadke SR, Verma IC, Puri RD, Gupta N, Kishnani PS, Mistry PK. Recombinant macrophage targeted enzyme replacement therapy for Gaucher disease in India. Indian Pediatrics 2011, 48: 779. PMID: 22080680, DOI: 10.1007/s13312-011-0128-4.Peer-Reviewed Original ResearchConceptsEnzyme replacement therapyReplacement therapyGaucher diseaseNeurological symptomsPlatelet countMean increaseImiglucerase enzyme replacement therapyBone marrow examinationCohort of patientsMonths of treatmentMild neurological symptomsImpairment of qualitySignificant neurological involvementBone painDesignRetrospective analysisLysosomal storage disorderMarrow examinationSymptomatic anemiaNeurological involvementIndian patientsSpleen volumeSpleen sizeGlucocerebrosidase levelsDrug infusionBone disease
2010
Bone marrow involvement in patients with posttransplant lymphoproliferative disorders: incidence and prognostic factors
Montanari F, O'Connor OA, Savage DG, Zain JM, Venkatraman S, McCormick EK, Crook MT, Tsao L, Sevilla DW, Bhagat G, Alobeid B. Bone marrow involvement in patients with posttransplant lymphoproliferative disorders: incidence and prognostic factors. Human Pathology 2010, 41: 1150-1158. PMID: 20381113, DOI: 10.1016/j.humpath.2009.11.016.Peer-Reviewed Original ResearchConceptsMonomorphic posttransplant lymphoproliferative disorderPosttransplant lymphoproliferative disorderBone marrow involvementPolymorphic posttransplant lymphoproliferative disordersDiffuse large B-cell lymphomaLarge B-cell lymphomaMarrow involvementLymphoproliferative disordersB-cell lymphomaSerologic parametersEpstein-Barr virus statusPosttransplant lymphoproliferative disorder patientsDe novo diffuse large B-cell lymphomaNovo diffuse large B-cell lymphomaBone marrow examinationElevated lactate dehydrogenaseBone marrow biopsyHodgkin lymphoma typeDiffuse large B-cell lymphoma casesLarge B-cell lymphoma casesB-cell lymphoma casesSensitive screening toolStaging biopsiesExtranodal involvementMarrow examination
2004
Acquired amegakaryocytic thrombocytopenia — four cases and a literature review
Lachowicz J, Post G, Moroff S, Mooney S. Acquired amegakaryocytic thrombocytopenia — four cases and a literature review. Journal Of Small Animal Practice 2004, 45: 507-514. PMID: 15515801, DOI: 10.1111/j.1748-5827.2004.tb00197.x.Peer-Reviewed Original ResearchConceptsImmune-mediated diseasesAssociated infectious diseasesPositive antibody titresAntibody titresInitial bone marrow examinationInfectious diseasesBone marrow examinationInitial platelet countMarrow examinationMegakaryocytic hypoplasiaPlatelet countPositive titresPostmortem examinationInfectious organismsMyeloid cell linesDiseaseEhrlichia canisDogsTitresB. burgdorferiPrednisoneCell linesBurgdorferiTreatmentMinimal changes
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply