2025
Structural and functional covariance architecture of major depressive disorder: A meta-analytic structural equation modeling approach to primary neuroimaging analysis
Gray J, Price L, Franklin C, Leonardo C, Chiang F, Choi K, Blangero J, Glahn D, Mayberg H, Fox P. Structural and functional covariance architecture of major depressive disorder: A meta-analytic structural equation modeling approach to primary neuroimaging analysis. Brain Organoid And Systems Neuroscience Journal 2025, 3: 96-106. DOI: 10.1016/j.bosn.2025.04.008.Peer-Reviewed Original ResearchVoxel-based morphometrySubgroup of MDD patientsSubgroups of MDDStructural equation modelingMDD patientsDepressive disorderResting-state functional magnetic resonance imagingAbnormalities of brain structureVoxel-based morphometry analysisFunctional magnetic resonance imagingMagnetic resonance imagingMDD patient groupGray matter densityBiomarkers of MDDNeuroimaging-based biomarkersClinical subgroupsMass-univariate analysesMass-univariate methodsMeta-analytic datasetNeuroimaging effectsNeuroimaging studiesMDDBrain areasBrain structuresMeta-analyticallyThe effects of alcohol use severity and polygenic risk on gray matter volumes in young adults
Chen Y, Li H, Luo X, Li G, Ide J, Li C. The effects of alcohol use severity and polygenic risk on gray matter volumes in young adults. Frontiers In Psychiatry 2025, 16: 1560053. PMID: 40433172, PMCID: PMC12106418, DOI: 10.3389/fpsyt.2025.1560053.Peer-Reviewed Original ResearchGray matter volumeAlcohol use severityPolygenic risk scoresAlcohol dependenceMatter volumeAlcohol misuseGenetic riskRegional gray matter volumeVoxel-based morphometry analysisStudies of alcohol dependencePosterior orbitofrontal cortexEffects of alcohol exposureSemi-Structured AssessmentGenetics of AlcoholismRisk of alcohol misuseAlcohol use behaviorsChronic alcohol consumptionHuman Connectome Project dataOrbitofrontal cortexSalience circuitsDrinking severityNeurotypical adultsRight insulaLingual gyriMorphometry analysisDifferential gray matter correlates and machine learning prediction of abuse and internalizing psychopathology in adolescent females
Heyn S, Keding T, Cisler J, McLaughlin K, Herringa R. Differential gray matter correlates and machine learning prediction of abuse and internalizing psychopathology in adolescent females. Scientific Reports 2025, 15: 651. PMID: 39753729, PMCID: PMC11698963, DOI: 10.1038/s41598-024-84616-5.Peer-Reviewed Original ResearchConceptsGray matter volumeVoxel-based morphometryInternalizing psychopathologyChildhood abuseAbuse experiencesPrefrontal cortexCingulate cortexAssociated with increased GMVVoxel-based morphometry analysisInterpersonal violenceDorsal prefrontal cortexDevelopment of psychopathologyAnterior cingulate cortexChildhood abuse historyChildhood abuse exposureT1 structural MRIDifferentiating gray matterPredictive of abuseAdolescent femalesSeverity of abuseDegree of overlapSupramarginal gyrusTrauma exposureStudy of interpersonal violenceIndividual psychopathology
2024
Structural brain changes associated with cocaine use and digital cognitive behavioral therapy in cocaine use disorder treatment
McCurdy L, DeVito E, Loya J, Nich C, Zhai Z, Kiluk B, Potenza M. Structural brain changes associated with cocaine use and digital cognitive behavioral therapy in cocaine use disorder treatment. Drug And Alcohol Dependence Reports 2024, 11: 100246. PMID: 38966567, PMCID: PMC11222934, DOI: 10.1016/j.dadr.2024.100246.Peer-Reviewed Original ResearchCocaine use disorderCognitive behavioral therapyCocaine useBehavioral therapyBrain changesBrain structuresWhole-brain voxel-based morphometry analysisCocaine use disorder treatmentLevel of cocaine useWeeks of outpatient treatmentVoxel-based morphometry analysisDigital cognitive behavioral therapyT1-weighted magnetic resonance imaging scansRight caudate bodyAssociated with cocaine useMethadone-maintained individualsGray matter volumeStructural brain changesFunction of engagementCaudate bodyRight caudateCUD treatmentMatter volumeUse disorderBilateral cerebellum
2023
Association Between False Memories and Delusions in Alzheimer Disease
McLachlan E, Ocal D, Burgess N, Reeves S, Howard R, Weiner M, Aisen P, Petersen R, Jack C, Jagust W, Trojanowki J, Toga A, Beckett L, Green R, Saykin A, Morris J, Perrin R, Shaw L, Khachaturian Z, Carrillo M, Potter W, Barnes L, Bernard M, González H, Ho C, Hsiao J, Jackson J, Masliah E, Masterman D, Okonkwo O, Perrin R, Ryan L, Silverberg N, Fleisher A, Truran Sacrey D, Fockler J, Conti C, Veitch D, Neuhaus J, Jin C, Nosheny R, Ashford M, Flenniken D, Kormos A, Montine T, Rafii M, Raman R, Jimenez G, Donohue M, Gessert D, Salazar J, Zimmerman C, Cabrera Y, Walter S, Miller G, Coker G, Clanton T, Hergesheimer L, Smith S, Adegoke O, Mahboubi P, Moore S, Pizzola J, Shaffer E, Sloan B, Harvey D, Forghanian-Arani A, Borowski B, Ward C, Schwarz C, Jones D, Gunter J, Kantarci K, Senjem M, Vemuri P, Reid R, Fox N, Malone I, Thompson P, Thomopoulos S, Nir T, Jahanshad N, DeCarli C, Knaack A, Fletcher E, Tosun-Turgut D, Rossi Chen S, Choe M, Crawford K, Yushkevich P, Das S, Koeppe R, Reiman E, Chen K, Mathis C, Landau S, Cairns N, Householder E, Franklin E, Bernhardt H, Taylor-Reinwald L, Korecka M, Figurski M, Neu S, Nho K, Risacher S, Apostolova L, Shen L, Foroud T, Nudelman K, Faber K, Wilmes K, Thal L, Silbert L, Lind B, Crissey R, Kaye J, Carter R, Dolen S, Quinn J, Schneider L, Pawluczyk S, Becerra M, Teodoro L, Dagerman K, Spann B, Brewer J, Vanderswag H, Ziolkowski J, Heidebrink J, Zbizek-Nulph L, Lord J, Mason S, Albers C, Knopman D, Johnson K, Villanueva-Meyer J, Pavlik V, Pacini N, Lamb A, Kass J, Doody R, Shibley V, Chowdhury M, Rountree S, Dang M, Stern Y, Honig L, Mintz A, Ances B, Winkfield D, Carroll M, Stobbs-Cucchi G, Oliver A, Creech M, Mintun M, Schneider S, Geldmacher D, Natelson Love M, Griffith R, Clark D, Brockington J, Marson D, Grossman H, Goldstein M, Greenber J, Mitsis E, Shah R, Lamar M, Samuels P, Duara R, Greig-Custo M, Rodriguez R, Albert M, Onyike C, Farrington L, Rudow S, Brichko R, Kielb S, Smith A, Ashok Raj B, Fargher K, Sadowski M, Wisniewski T, Shulman M, Faustin A, Rao J, Castro K, Ulysse A, Chen S, Sheikh M, Singleton-Garvin J, Murali Doraiswamy P, Petrella J, James O, Wong T, Borges-Neto S, Karlawish J, Wolk D, Vaishnavi S, Clark C, Arnold S, Smith C, Jicha G, El Khouli R, Raslau F, Lopez O, Oakley M, Simpson D, Porsteinsson A, Martin K, Kowalski N, Keltz M, Goldstein B, Makino K, Seleem Ismail M, Brand C, Thai G, Pierce A, Yanez B, Sosa E, Witbracht M, Kelley B, Nguyen T, Womack K, Mathews D, Quiceno M, Levey A, Lah J, Hajjar I, Cellar J, Burns J, Swerdlow R, Brooks W, Silverman D, Kremen S, Apostolova L, Tingus K, Lu P, Bartzokis G, Woo E, Teng E, Graff-Radford N, Parfitt F, Poki-Walker K, Farlow M, Hake A, Matthews B, Brosch J, Herring S, van Dyck C, Mecca A, Good S, MacAvoy M, Carson R, Varma P, Chertkow H, Vaitekunis S, Hosein C, Black S, Stefanovic B, Heyn C, Robin Hsiung G, Kim E, Mudge B, Sossi V, Feldman H, Assaly M, Finger E, Pasternak S, Rachinsky I, Kertesz A, Drost D, Rogers J, Grant I, Muse B, Rogalski E, Robson J, Marsel Mesulam M, Kerwin D, Wu C, Johnson N, Liposki K, Weintraub S, Bonakdarpour B, Pomara N, Hernando R, Sarrael A, Rosen H, Miller B, Perry D, Scott Turner R, Johnson K, Reynolds B, McCann K, Poe J, Sperling R, Johnson K, Marshall G, Yesavage J, Taylor J, Chao S, Coleman J, White J, Lane B, Rosen A, Tinklenberg J, Belden C, Atri A, Clark K, Zamrini E, Sabbagh M, Killiany R, Stern R, Mez J, Kowall N, Budson A, Obisesan T, Ntekim O, Wolday S, Khan J, Nwulia E, Nadarajah S, Lerner A, Ogrocki P, Tatsuoka C, Fatica P, Maillard P, Olichney J, Carmichael O, Bates V, Capote H, Rainka M, Borrie M, Lee T, Bartha R, Johnson S, Asthana S, Carlsson C, Perrin A, Burke A, Scharre D, Kataki M, Tarawneh R, Hart D, Zimmerman E, Celmins D, Miller D, Boles L, Ekstam Smith K, Koleva H, Shim H, Won Nam K, Schultz S, Williamson J, Craft S, Cleveland J, Yang M, Sink K, Ott B, Drake J, Tremont G, Daielllo L, Ritter A, Bernick C, Munic D, O'Connelll A, Mintzer J, Wiliams A, Masdeu J, Shi J, Garcia A, Newhouse P, Potkin S, Salloway S, Malloy P, Correia S, Kittur S, Pearlson G, Blank K, Anderson K, Flashman L, Seltzer M, Hynes M, Santulli R, Relkin N, Chiang G, Lin M, Ravdin L, Lee A, Neylan T, Grafman J, Danowski S, Nguyen-Barrera C, Hayes J, Finley S, Bernstein M, Foster N, Kim S, Sood A, Blanchard K, Arfanakis K, Fleischman D, Varon D, Reist C, Sadowsky C, Martinez W, Villena T, Peskind E, Petrie E, Li G, Mackin S, Drake E, Nelson C, Bikford D, Butters M, Zmuda M, Reyes D, Ho Au Y, Scherer K, Catalinotto D, Stark S, Ong E, Fernandez D. Association Between False Memories and Delusions in Alzheimer Disease. JAMA Psychiatry 2023, 80: 700-709. PMID: 37223934, PMCID: PMC10209823, DOI: 10.1001/jamapsychiatry.2023.1012.Peer-Reviewed Original ResearchConceptsRey Auditory Verbal Learning TestFalse recognitionFalse memoriesRegional brain volumesWhole-brain voxel-based morphometry analysisAuditory Verbal Learning TestAlzheimer's Disease Neuroimaging InitiativeDisease Assessment ScalePresence of delusionsBrain regionsVerbal Learning TestFusiform gyrus volumeFalse recognition scoresHippocampal volumeLower regional brain volumesVoxel-based morphometry analysisCross-sectional studyDisease Neuroimaging InitiativeLogistic regression modelingSame brain regionsBrain volumeAlzheimer's diseaseLearning TestRight hippocampal volumeDelusion formation
2022
Language reorganization in patients with left-hemispheric gliomas is associated with increased cortical volume in language-related areas and in the default mode network
Pasquini L, Jenabi M, Peck K, Holodny A. Language reorganization in patients with left-hemispheric gliomas is associated with increased cortical volume in language-related areas and in the default mode network. Cortex 2022, 157: 245-255. PMID: 36356409, PMCID: PMC10201933, DOI: 10.1016/j.cortex.2022.09.014.Peer-Reviewed Original ResearchConceptsIncreased cortical volumeInferior frontal gyrusLanguage laterality indexPosterior cingulate cortexSuperior temporal gyrusVoxel-based morphometryRight inferior frontal gyrusRight posterior cingulate cortexRight superior temporal gyrusLeft-hemisphere gliomasCortical volumeFusiform gyrusAtypical languageCingulate cortexAD patientsRight dorsal lateral prefrontal cortexRight anterior cingulate cortexDorsal lateral prefrontal cortexVoxel-based morphometry analysisMode network nodesAnterior cingulate cortexRight fusiform gyrusLanguage-related areasRight precentral gyrusMeasured cortical volumeGray matter volumetric correlates of dimensional impulsivity traits in children: Sex differences and heritability
Chen Y, Ide JS, Li CS, Chaudhary S, Le TM, Wang W, Zhornitsky S, Zhang S, Li C. Gray matter volumetric correlates of dimensional impulsivity traits in children: Sex differences and heritability. Human Brain Mapping 2022, 43: 2634-2652. PMID: 35212098, PMCID: PMC9057091, DOI: 10.1002/hbm.25810.Peer-Reviewed Original ResearchConceptsGray matter volumeImpulsivity traitsPositive urgencyVolumetric correlatesSensation seekingHigher positive urgencyMid-cingulate cortexSex differencesVoxel-based morphometry analysisSmaller gray matter volumeImpulsivity dimensionsSubsample of twinsDistinct correlatesCingulate cortexPrecentral gyrusSubcortical gray matter volumesMatter volumeTotal intracranial volumeSeekingImpulsivityMorphometry analysisPrevious researchInsulaCorrelatesGirlsIncreased left dorsolateral prefrontal cortex density following escitalopram intake during relearning: a randomized, placebo-controlled trial in healthy humans
Vanicek T, Reed M, Seiger R, Godbersen G, Klöbl M, Unterholzner J, Spurny-Dworak B, Gryglewski G, Handschuh P, Schmidt C, Kraus C, Stimpfl T, Rupprecht R, Kasper S, Lanzenberger R. Increased left dorsolateral prefrontal cortex density following escitalopram intake during relearning: a randomized, placebo-controlled trial in healthy humans. Therapeutic Advances In Psychopharmacology 2022, 12: 20451253221132085. PMID: 36420117, PMCID: PMC9677158, DOI: 10.1177/20451253221132085.Peer-Reviewed Original ResearchLeft dorsolateral prefrontal cortexAssociative learning taskNon-emotional contentDorsolateral prefrontal cortexVoxel-based morphometry analysisEmotional processingExecutive functionLearning taskNeurobiological processesVoxel-based morphometryPrefrontal cortexBrain plasticityEscitalopram intakeNeural plasticityBrain areasNeuroplastic processesBlood levelsBrain structuresHealthy individualsMorphometry analysisDouble-blind placebo controlGray matterStress-induced dendritic atrophySelective serotonin reuptake inhibitorsPlacebo intake
2019
The interrelationship of body mass index with gray matter volume and resting-state functional connectivity of the hypothalamus
Le TM, Liao DL, Ide J, Zhang S, Zhornitsky S, Wang W, Li CR. The interrelationship of body mass index with gray matter volume and resting-state functional connectivity of the hypothalamus. International Journal Of Obesity 2019, 44: 1097-1107. PMID: 31796869, PMCID: PMC8643195, DOI: 10.1038/s41366-019-0496-8.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityWhole-brain multiple regressionGray matter volumeInsula connectivityBody mass indexFunctional connectivitySeed-based resting-state functional connectivityMatter volumeSuperior parietal lobuleVoxel-based morphometry analysisMultiple regressionConclusionsThe current findingsBody weightCognitive controlMultiple brain circuitsBrain mechanismsIndividual differencesInhibitory controlParietal lobuleHypothalamic connectivityMass indexMediation analysisBrain circuitsHigher Body Mass IndexCurrent findings
2014
Neural plasticity in fathers of human infants
Kim P, Rigo P, Mayes LC, Feldman R, Leckman JF, Swain JE. Neural plasticity in fathers of human infants. Social Neuroscience 2014, 9: 522-535. PMID: 24958358, PMCID: PMC4144350, DOI: 10.1080/17470919.2014.933713.Peer-Reviewed Original ResearchConceptsFathers' brainsNeural plasticityLateral prefrontal cortexCurrent longitudinal studyPosterior cingulate cortexVoxel-based morphometry analysisGray matter volumeNeural basisCognitive developmentNeural regionsNeural changesOrbitofrontal cortexPrefrontal cortexWeeks postpartumHuman fathersParental motivationCingulate cortexHuman infantsMood symptomsBrain regionsLongitudinal studyPostpartum mood symptomsMatter volumeMorphometry analysisHuman mothers
2013
Anatomical Coupling between Distinct Metacognitive Systems for Memory and Visual Perception
McCurdy L, Maniscalco B, Metcalfe J, Liu K, de Lange F, Lau H. Anatomical Coupling between Distinct Metacognitive Systems for Memory and Visual Perception. Journal Of Neuroscience 2013, 33: 1897-1906. PMID: 23365229, PMCID: PMC4696871, DOI: 10.1523/jneurosci.1890-12.2013.Peer-Reviewed Original ResearchConceptsMetacognitive efficiencyFrontal polar regionsGray matter volumeMetacognitive systemKinds of metacognitionMatter volumeDistinct brain structuresVoxel-based morphometry analysisMemory taskBehavioral correlationsMetacognitive mechanismsMetacognitive tasksModel comparison analysisMemory processingPrecuneus volumeVisual perceptionAnatomical couplingStructural covariationPsychophysical measuresPrecuneus regionsMetacognitionHuman brainBrain structuresMorphometry analysisTask
2011
Olfactocentric paralimbic cortex morphology in adolescents with bipolar disorder
Wang F, Kalmar JH, Womer FY, Edmiston EE, Chepenik LG, Chen R, Spencer L, Blumberg HP. Olfactocentric paralimbic cortex morphology in adolescents with bipolar disorder. Brain 2011, 134: 2005-2012. PMID: 21666263, PMCID: PMC3122371, DOI: 10.1093/brain/awr124.Peer-Reviewed Original ResearchConceptsParalimbic corticesBipolar disorderHigh-resolution structural magnetic resonanceGray matter volume differencesVoxel-based morphometry analysisHealthy comparison adolescentsStructural magnetic resonanceSmall volume correctionSuperior temporal gyrusBipolar disorder pathologyNeurovegetative functionsBipolar disorder phenotypeTemporopolar cortexSignificant volume decreaseParalimbic regionsCortex morphologyTemporal gyrusCortexDisordersMorphometry analysisDisorder phenotypesInferior prefrontalCortex structureDisorder pathologyAdolescents
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply