2018
The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer
Caldwell A, Coleby R, Tovar C, Stammnitz M, Kwon Y, Owen R, Tringides M, Murchison E, Skjødt K, Thomas G, Kaufman J, Elliott T, Woods G, Siddle H. The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer. ELife 2018, 7: e35314. PMID: 30103855, PMCID: PMC6092122, DOI: 10.7554/elife.35314.Peer-Reviewed Original ResearchConceptsDevil facial tumour 2Devil Facial Tumour 1Contagious cancerExpressed MHC class I allelesLoss of MHCClass I allelesMHC class I allelesNon-polymorphicAllogeneic antigensTumors 2Evolutionary trajectoriesTumor 1Disease 2Tasmanian devilI allelesReduced immunogenicityCancerMHCIn vivoWidespread transmissionHost
2012
Increased expression of tumor-associated antigens in pediatric and adult ependymomas: implication for vaccine therapy
Yeung JT, Hamilton RL, Okada H, Jakacki RI, Pollack IF. Increased expression of tumor-associated antigens in pediatric and adult ependymomas: implication for vaccine therapy. Journal Of Neuro-Oncology 2012, 111: 103-111. PMID: 23179498, PMCID: PMC3546121, DOI: 10.1007/s11060-012-0998-x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overAntigens, NeoplasmBrainBrain NeoplasmsCancer VaccinesChildChild, PreschoolEpendymomaFemaleGene Expression Regulation, NeoplasticHistocompatibility Antigens Class IHumansInfantInhibitor of Apoptosis ProteinsInterleukin-13 Receptor alpha1 SubunitMaleMiddle AgedReceptor, EphA2SurvivinWT1 ProteinsConceptsTumor-associated antigensMore tumor-associated antigensIL-13Rα2Positive stainingAdult ependymomasMultiple peptides vaccineNormal brain tissueGlioma vaccinesImmunotherapy approachesVaccine therapyPediatric casesAdult casesTumor recurrenceClinical trialsPeptide vaccinePediatric ependymomaNormal brainEpendymomaBrain tissuePediatric gliomasTumor 1SurvivinStainingEphA2Vaccine
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