The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer
Caldwell A, Coleby R, Tovar C, Stammnitz M, Kwon Y, Owen R, Tringides M, Murchison E, Skjødt K, Thomas G, Kaufman J, Elliott T, Woods G, Siddle H. The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer. ELife 2018, 7: e35314. PMID: 30103855, PMCID: PMC6092122, DOI: 10.7554/elife.35314.Peer-Reviewed Original ResearchConceptsDevil facial tumour 2Devil Facial Tumour 1Contagious cancerExpressed MHC class I allelesLoss of MHCClass I allelesMHC class I allelesNon-polymorphicAllogeneic antigensTumors 2Evolutionary trajectoriesTumor 1Disease 2Tasmanian devilI allelesReduced immunogenicityCancerMHCIn vivoWidespread transmissionHost
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