2024
Long-term Outcomes Following Colectomy and Liver Transplantation for Inflammatory Bowel Disease with Primary Sclerosing Cholangitis.
Matar A, Falconer E, LaBella M, Kapadia M, Justiniano C, Olortegui K, Steinhagen R, Schultz K, Pratap A, Leeds I, Weaver L, Gaertner W, Finger E, Thompson M, Fair L, Fichera A, Lovasik B, Chapman W, McGeoch C, Camacho M, Kazimi M, Kim S, Shaffer V, Srinivasan J. Long-term Outcomes Following Colectomy and Liver Transplantation for Inflammatory Bowel Disease with Primary Sclerosing Cholangitis. Annals Of Surgery 2024 PMID: 39258375, PMCID: PMC12184207, DOI: 10.1097/sla.0000000000006533.Peer-Reviewed Original ResearchTotal abdominal colectomyLong-term outcomesIleal pouch anal anastomosisMedically refractory diseaseLiver transplantationPSC-IBDRecurrent PSCRefractory diseaseBiliary complicationsMedian timeLong-term outcomes of patientsBowel diseasePost-LT survivalOutcomes of patientsPrimary sclerosing cholangitisFraction of patientsPSC-IBD patientsLong-term survivalInflammatory bowel diseasePost-LTSclerosing cholangitisPediatric patientsAbdominal colectomyEnd ileostomyLT survival
2022
Epidemiology and outcomes of surgical site infections among pediatric liver transplant recipients
Banach DB, Lopez‐Verdugo F, Sanchez‐Garcia J, Tran A, Gomez‐Llerena A, Munoz‐Abraham A, Bertacco A, Valentino PL, Yoo P, Dembry L, Mulligan DC, Ekong UD, Emre SH, Rodriguez‐Davalos M. Epidemiology and outcomes of surgical site infections among pediatric liver transplant recipients. Transplant Infectious Disease 2022, 24: e13941. PMID: 35989545, DOI: 10.1111/tid.13941.Peer-Reviewed Original ResearchConceptsSurgical site infectionLiver transplant recipientsLiver transplantationBiliary complicationsGraft recipientsTransplant recipientsSite infectionRisk factorsOutcomes of SSIPediatric liver transplant recipientsLong-term graftPediatric liver transplantationRetrospective descriptive analysisPrimary endpointHospital daysPatient agePediatric populationPatient survivalSignificant causeComplicationsPatientsRecipientsOutcomesInfectionIncidenceIndex Admission Cholecystectomy and Recurrence of Pediatric Gallstone Pancreatitis: Multicenter Cohort Analysis.
Muñoz Abraham AS, Osei H, Bajinting A, Cowles RA, Greenspon J, Hosfield BD, Keller MS, Landman MP, Owens H, Shaughnessy MP, St Peter SD, Sujka J, Vogel AM, Villalona GA. Index Admission Cholecystectomy and Recurrence of Pediatric Gallstone Pancreatitis: Multicenter Cohort Analysis. Journal Of The American College Of Surgeons 2022, 234: 352-358. PMID: 35213498, DOI: 10.1097/xcs.0000000000000062.Peer-Reviewed Original ResearchConceptsGallstone pancreatitisEarly cholecystectomyIndex admissionRecurrent pancreatitisRecurrence rateMean body mass indexIndex admission cholecystectomyMean age 13.5Multicenter cohort analysisTiming of cholecystectomyBody mass indexBiliary complicationsInterval cholecystectomyIndex dischargeCholecystectomy ratesGroup patientsMost patientsLaboratory characteristicsMild pancreatitisPediatric patientsRetrospective reviewMass indexCholecystectomyCohort analysisPancreatitisLiver allograft findings of donation after cardiac death versus brain death in recipients with hepatitis C related cirrhosis: a matched histologic comparison
Byrnes K, Vachharajani N, Doyle MM, Nalbantoglu I. Liver allograft findings of donation after cardiac death versus brain death in recipients with hepatitis C related cirrhosis: a matched histologic comparison. Human Pathology 2022, 122: 25-31. PMID: 35085598, DOI: 10.1016/j.humpath.2022.01.005.Peer-Reviewed Original ResearchConceptsBiliary complicationsDCD casesLiver allograftsCardiac deathHistologic featuresBrain death (DBD) recipientsDCD liver allograftsPostoperative biliary complicationsBile duct injuryCold ischemia timeHepatitis C virusOrgan transplantation increasesBiliary alterationsDBD recipientsDCD allograftsDCD recipientsPortal edemaDuct injuryGraft survivalHepatitis CPortal inflammationOverall survivalTransplantation increasesLiver biopsyClinical outcomes
2020
Role of Prophylactic Cholecystectomy After Endoscopic Sphincterotomy for Biliary Stone Disease: A Systematic Review and Meta-analysis.
McCarty TR, Farrelly J, Njei B, Jamidar P, Muniraj T. Role of Prophylactic Cholecystectomy After Endoscopic Sphincterotomy for Biliary Stone Disease: A Systematic Review and Meta-analysis. Annals Of Surgery 2020, 273: 667-675. PMID: 32590541, DOI: 10.1097/sla.0000000000003977.Peer-Reviewed Original ResearchConceptsRecurrent biliary painProphylactic cholecystectomyBile duct stonesMeta-analysisSystematic reviewBiliary painDuct stonesCommon bile duct stonesBiliary stone diseaseSubset of patientsCochrane Library databasesRisk of mortalityConfidence intervalsRate of pancreatitisPooled effect sizeSearch of PubMedPreferred Reporting ItemsRandom-effects modelWeb of ScienceBiliary complicationsEventual cholecystectomyComplication rateEndoscopic cholangiopancreatographyEndoscopic sphincterotomyBiliary sphincterotomy
2019
Tacrolimus and Indomethacin Are Safe and Effective at Reducing Pancreatitis After Endoscopic Retrograde Cholangiopancreatography in Patients Who Have Undergone Liver Transplantation
Thiruvengadam NR, Forde KA, Chandrasekhara V, Ahmad NA, Ginsberg GG, Khungar V, Kochman ML. Tacrolimus and Indomethacin Are Safe and Effective at Reducing Pancreatitis After Endoscopic Retrograde Cholangiopancreatography in Patients Who Have Undergone Liver Transplantation. Clinical Gastroenterology And Hepatology 2019, 18: 1224-1232.e1. PMID: 31622734, DOI: 10.1016/j.cgh.2019.10.014.Peer-Reviewed Original ResearchConceptsEndoscopic retrograde cholangiopancreatographyRisk of PEPDevelopment of PEPLiver transplantationTrough levelsBiliary complicationsIndomethacin useRectal indomethacinRetrospective studyRetrograde cholangiopancreatographyERCP proceduresOdds ratioMixed-effects multivariable logistic regressionEffectiveness of tacrolimusIncidence of PEPTacrolimus trough levelsCommon adverse eventsChronic kidney diseaseGlomerular filtration rateMultivariable logistic regressionRate of pancreatitisAddition of indomethacinChronic rejectionSevere PEPStable doseStaged Biliary Reconstruction After Orthotopic Liver Transplantation: A Practical Surgical Strategy for High-Acuity Adult Recipients
Pearson T, Zimmerman M, Kim J, Palines P, Eriksen C, Wong M, Selim M, Markovic D, Hong J. Staged Biliary Reconstruction After Orthotopic Liver Transplantation: A Practical Surgical Strategy for High-Acuity Adult Recipients. Transplantation Direct 2019, 5: e482. PMID: 31579810, PMCID: PMC6739041, DOI: 10.1097/txd.0000000000000924.Peer-Reviewed Original ResearchOrthotopic liver transplantationBiliary reconstructionBiliary complicationsLiver transplantationGroup IGroup IISurgical strategyIntraoperative packed red blood cell transfusionAssociated with inferior patient outcomesPacked red blood cell transfusionAdult orthotopic liver transplantationFailure-free survival rateGraft failure-free survivalPediatric orthotopic liver transplantationEnd-stage liver disease scoreRed blood cell transfusionPretransplant renal replacement therapyFailure-free survivalHigh-acuity recipientsEstimated blood lossBlood cell transfusionMean follow-upLow-risk patientsLiver Disease scoreRenal replacement therapy
2018
Staged biliary reconstruction after liver transplantation: A novel surgical strategy for high acuity pediatric transplant recipients
Kim J, Zimmerman M, Lerret S, Scott J, Voulgarelis S, Fons R, Vitola B, Telega G, Hoffman G, Berens R, Hong J. Staged biliary reconstruction after liver transplantation: A novel surgical strategy for high acuity pediatric transplant recipients. Surgery 2018, 165: 323-328. PMID: 30268374, DOI: 10.1016/j.surg.2018.08.022.Peer-Reviewed Original ResearchConceptsPediatric orthotopic liver transplantationOrthotopic liver transplantationPediatric transplant recipientsLiver transplantationGroup IBiliary complicationsTransplant recipientsBiliary reconstructionRed blood cell transfusion volumeGroup IIRoux-en-Y hepaticojejunostomyComplex hepatobiliary surgeryMedian Follow-UpNovel surgical strategyComparing group IStaged operative approachSignificant patient morbidityRoux-en-YTransfusion volumeMedian ageSurgical strategyPostoperative outcomesHepatobiliary surgeryBiliary anastomosisPatient morbidityEmerging Innovations in Liver Preservation and Resuscitation
Kim J, Zimmerman M, Hong J. Emerging Innovations in Liver Preservation and Resuscitation. Transplantation Proceedings 2018, 50: 2308-2316. PMID: 30316348, DOI: 10.1016/j.transproceed.2018.03.080.Peer-Reviewed Original ResearchConceptsOrthotopic liver transplantationPrimary nonfunctionIncreased susceptibility to ischemia-reperfusion injuryMachine perfusionClinical trialsOutcome of orthotopic liver transplantationEra of organ shortageSusceptible to ischemia-reperfusion injuryMarginal graftsIncidence of primary nonfunctionNormothermic MPIschemia-reperfusion injuryMethods of organ preservationMarginal liver graftsDecreasing oxygen demandBiliary complicationsOrgan preservation timeLiver transplantationLiver graftsIncreased riskOrgan preservationHypothermic MPAnimal studiesBlood flow rateOrgan shortage
2016
What Every Hepatologist Should Know about Liver Transplantation
Yoo P, Mulligan D. What Every Hepatologist Should Know about Liver Transplantation. 2016, 608-616. DOI: 10.1002/9781119127437.ch93.Peer-Reviewed Original ResearchLiver transplantationPiggyback techniqueExcellent long-term patient outcomesLong-term patient outcomesHepatic venous complicationsRetrohepatic vena cavaDonor liver transplantationLiver transplant patientsRisk of complicationsBiliary complicationsSplit liverTransplant patientsTransplant recipientsVenous complicationsDonor transplantsMultidisciplinary careVena cavaDonor poolPatient outcomesTransplant operationSurgical techniqueOrgan allocationPhysiologic circumstancesComplicationsSuccessful outcome
2014
Segmental Grafts in Adult and Pediatric Liver Transplantation: Improving Outcomes by Minimizing Vascular Complications
Rodriguez-Davalos MI, Arvelakis A, Umman V, Tanjavur V, Yoo PS, Kulkarni S, Luczycki SM, Schilsky M, Emre S. Segmental Grafts in Adult and Pediatric Liver Transplantation: Improving Outcomes by Minimizing Vascular Complications. JAMA Surgery 2014, 149: 63-70. PMID: 24284803, DOI: 10.1001/jamasurg.2013.3384.Peer-Reviewed Original ResearchConceptsDonor liver transplantSegmental graftsRight lobeLiver transplantVascular complicationsSegmental allograftsDeceased donorsLateral segmentConsecutive liver transplant patientsDonor graft recipientsHepatic artery stenosisReduced-size graftsWaiting list mortalityLiver transplant patientsPortal vein thrombosisPediatric liver transplantationMultidisciplinary team approachInnovative surgical techniquesBiliary complicationsSegmental transplantsStrict patientGraft survivalList mortalityLiver transplantationTransplant patients
2010
What Hepatologists Should Know about Liver Transplant Surgery
Mekeel K, Mulligan D. What Hepatologists Should Know about Liver Transplant Surgery. 2010, 305-316. DOI: 10.1002/9781444325249.ch30.Peer-Reviewed Original ResearchLiver transplantationExcellent long-term patient outcomesLong-term patient outcomesDonor liver transplantationLiver transplant surgeryBiliary complicationsDonor allograftsMultidisciplinary careSurgical outcomesTransplant surgeryDonor poolPatient outcomesTransplant operationHepatic anatomyPhysiologic eventsHepatologistsComplicationsPatientsTransplantationOutcomesAllograftsSurgeryHepatectomyDiagnosisCare
2001
Vascular and extravascular complications of liver transplantation: comprehensive evaluation with three-dimensional contrast-enhanced volumetric MR imaging and MR cholangiopancreatography.
Pandharipande P, Lee V, Morgan G, Teperman L, Krinsky G, Rofsky N, Roy M, Weinreb J. Vascular and extravascular complications of liver transplantation: comprehensive evaluation with three-dimensional contrast-enhanced volumetric MR imaging and MR cholangiopancreatography. American Journal Of Roentgenology 2001, 177: 1101-7. PMID: 11641180, DOI: 10.2214/ajr.177.5.1771101.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnastomosis, SurgicalAngiography, Digital SubtractionCholangiographyCholestasis, ExtrahepaticCommon Bile Duct DiseasesFemaleHumansImage Processing, Computer-AssistedImaging, Three-DimensionalLiverLiver TransplantationMagnetic Resonance AngiographyMagnetic Resonance ImagingMaleMiddle AgedPostoperative ComplicationsSensitivity and SpecificityVascular DiseasesConceptsDigital subtraction angiographyMR cholangiopancreatographyLiver transplantSubtraction angiographyMR imagingVolumetric MR imagingConsecutive adult patientsSubset of patientsHepatocellular carcinoma recurrenceMR angiography examinationsMR imaging examinationsBiliary complicationsDisease underestimationExtrahepatic complicationsLiver transplantationAbnormal findingsAdult patientsCarcinoma recurrenceMR imaging strategiesAngiography examinationsVascular diseaseImaging examinationsMost recipientsCholangiopancreatographySimultaneous vascular
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