2023
Trends in Racial Inequalities in the Administration of Opioid and Non-opioid Pain Medication in US Emergency Departments Across 1999–2020
Thompson T, Stathi S, Buckley F, Shin J, Liang C. Trends in Racial Inequalities in the Administration of Opioid and Non-opioid Pain Medication in US Emergency Departments Across 1999–2020. Journal Of General Internal Medicine 2023, 39: 214-221. PMID: 37698724, PMCID: PMC10853122, DOI: 10.1007/s11606-023-08401-2.Peer-Reviewed Original ResearchConceptsUS emergency departmentsEmergency departmentRacial disparitiesPain medicationNon-opioid analgesicsWhite patientsNational Hospital Ambulatory Medical Care SurveyReceipt of pain medicationMagnitude of racial disparitiesCross-sectional probability samplePain treatmentBlack patientsPrescribed pain medicationPopulation-weighted estimatesRelative risk regressionSample of visitsShort-stay hospitalsNon-opioid pain medicationsSeverity of painEquitable healthcareCare SurveyED visitsAdministration of opioidsInsurance statusPotential confoundersExamining Mental Health, Education, Employment, and Pain in Sickle Cell Disease
Harris K, Preiss L, Varughese T, Bauer A, Calhoun C, Treadwell M, Masese R, Hankins J, Hussain F, Glassberg J, Melvin C, Gibson R, King A. Examining Mental Health, Education, Employment, and Pain in Sickle Cell Disease. JAMA Network Open 2023, 6: e2314070. PMID: 37200033, PMCID: PMC10196879, DOI: 10.1001/jamanetworkopen.2023.14070.Peer-Reviewed Original ResearchConceptsSickle cell diseasePain frequencyMedical record abstractionPain severityMental healthHydroxyurea usePain medicationRecord abstractionCell diseaseMAIN OUTCOMEAdult Sickle Cell QualityElectronic medical record abstractionSickle Cell Disease Implementation ConsortiumDaily pain medicationHigher pain frequencySeverity of painRegular blood transfusionsMental health diagnosesPatient registry dataCross-sectional analysisAssociation of educationEmployment statusPain episodesPain reductionPain scores
2020
Prospective Study of Use of Edmonton Symptom Assessment Scale Versus Routine Symptom Management During Weekly Radiation Treatment Visits.
Goyal UD, Riegert K, Davuluri R, Ong S, Yi SK, Dougherty ST, Hsu CC. Prospective Study of Use of Edmonton Symptom Assessment Scale Versus Routine Symptom Management During Weekly Radiation Treatment Visits. JCO Oncology Practice 2020, 16: e1029-e1035. PMID: 32384015, DOI: 10.1200/jop.19.00465.Peer-Reviewed Original ResearchConceptsEdmonton Symptom Assessment ScaleImproved symptom severitySymptom managementSymptom severityPostintervention groupTreatment visitsInstitutional quality improvement projectSeverity of painLoss of appetiteSymptom Assessment ScaleMultivariate logistic regressionQuality improvement projectPreintervention groupPain medicationPatient's symptomsCommon symptomsProspective studyAppetite stimulantIndependent associationProvider assessmentPhysician reviewMost physiciansTherapeutic interventionsAssessment ScaleLogistic regression
2019
The Relationship between Mental Health, Educational Attainment, Employment Outcomes, and Pain in Sickle Cell Disease
Harris K, Varughese T, Bauer A, Howdeshell S, Calhoun C, Abel R, King A. The Relationship between Mental Health, Educational Attainment, Employment Outcomes, and Pain in Sickle Cell Disease. Blood 2019, 134: 419. DOI: 10.1182/blood-2019-129874.Peer-Reviewed Original ResearchLength of painSickle cell diseaseSeverity of painHistory of depressionSevere painPain outcomesAnnual household incomePain crisisPain frequencyCell diseaseSocioeconomic statusMultivariate analysisSeverity of SCDSignificant associationEmployment statusMental healthHigher pain frequencyHospital admission frequencyEnd-organ damageFrequency of painVariety of complicationsPatients' educational attainmentCross-sectional studyOnly significant associationPatient survey dataPresentation of Ischaemic Foot
Edmonds M, Simmgen M, Sumpio B. Presentation of Ischaemic Foot. 2019, 213-219. DOI: 10.1007/978-3-319-17918-6_18.Peer-Reviewed Original Research
2018
Minocycline does not affect experimental pain or addiction-related outcomes in opioid maintained patients
Arout CA, Waters AJ, MacLean RR, Compton P, Sofuoglu M. Minocycline does not affect experimental pain or addiction-related outcomes in opioid maintained patients. Psychopharmacology 2018, 236: 2857-2866. PMID: 30564869, PMCID: PMC6581631, DOI: 10.1007/s00213-018-5146-7.Peer-Reviewed Original ResearchConceptsOpioid-induced hyperalgesiaCold pressor testOpioid use disorderSerum cytokinesPain thresholdUse disordersAddiction-related outcomesProinflammatory serum cytokinesActivation of microgliaSeverity of painEcological momentary assessmentEnd of treatmentHuman laboratory studiesTest sessionsOpioid cravingMinocycline treatmentOpioid toleranceAgonist treatmentPain sensitivityVisit 1Minocycline effectsPressor testExperimental painPreclinical studiesGo/No-Go task
2016
Inherited erythromelalgia due to mutations in SCN9A: natural history, clinical phenotype and somatosensory profile
McDonnell A, Schulman B, Ali Z, Dib-Hajj SD, Brock F, Cobain S, Mainka T, Vollert J, Tarabar S, Waxman SG. Inherited erythromelalgia due to mutations in SCN9A: natural history, clinical phenotype and somatosensory profile. Brain 2016, 139: 1052-1065. PMID: 26920677, DOI: 10.1093/brain/aww007.Peer-Reviewed Original ResearchConceptsPain attacksQuantitative sensory testingDepression Scale scoresHospital AnxietySomatosensory profilesPain phenotypesOlfaction testingClinical characterizationSensory testingScale scoreNatural historyDepression Scale depression scoreDepth clinical characterizationSodium channelsSeverity of painPattern of painSmall fiber neuropathyTotal Hospital AnxietyWeek observation periodVoltage-gated sodium channelsSame mutationHuman pain syndromesUnaffected sitesOrthostatic hypotensionPain syndrome
2015
Weight loss outcomes in patients with pain
Masheb RM, Lutes LD, Kim HM, Holleman RG, Goodrich DE, Janney CA, Kirsh S, Higgins DM, Richardson CR, Damschroder LJ. Weight loss outcomes in patients with pain. Obesity 2015, 23: 1778-1784. PMID: 26237112, DOI: 10.1002/oby.21160.Peer-Reviewed Original ResearchConceptsWeight loss outcomesSuboptimal weight loss outcomesPain severityPain typesLoss outcomesBehavioral weight management programWeight lossSeverity of painOverweight/obesityWeight management programPhysical activity outcomesSevere painArthritis painPain dataSecondary data analysisPainActivity outcomesPatientsSeverityLinear mixed modelsOutcomesSignificant differencesOnly minor improvementsHigh rateLess weightDevelopment, Content Validity, and User Review of a Web-based Multidimensional Pain Diary for Adolescent and Young Adults With Sickle Cell Disease
Bakshi N, Stinson J, Ross D, Lukombo I, Mittal N, Joshi S, Belfer I, Krishnamurti L. Development, Content Validity, and User Review of a Web-based Multidimensional Pain Diary for Adolescent and Young Adults With Sickle Cell Disease. The Clinical Journal Of Pain 2015, 31: 580-590. PMID: 25565585, DOI: 10.1097/ajp.0000000000000195.Peer-Reviewed Original ResearchConceptsSickle cell diseasePain diaryHealth care utilizationElectronic pain diaryYoung adultsCare utilizationCell diseasePoor health-related qualityContent validityVaso-occlusive painDaily pain diarySeverity of painHealth-related qualityPain burdenModification of itemsPain experiencePainPatientsEnd-user reviewsElectronic diaryDiseaseAdultsAdolescentsPsychometric propertiesDiary
2014
Chronic Pancreatitis Pain Pattern and Severity Are Independent of Abdominal Imaging Findings
Wilcox CM, Yadav D, Ye T, Gardner TB, Gelrud A, Sandhu BS, Lewis MD, Al-Kaade S, Cote GA, Forsmark CE, Guda NM, Conwell DL, Banks PA, Muniraj T, Romagnuolo J, Brand RE, Slivka A, Sherman S, Wisniewski SR, Whitcomb DC, Anderson MA. Chronic Pancreatitis Pain Pattern and Severity Are Independent of Abdominal Imaging Findings. Clinical Gastroenterology And Hepatology 2014, 13: 552-560. PMID: 25424572, PMCID: PMC5019545, DOI: 10.1016/j.cgh.2014.10.015.Peer-Reviewed Original ResearchConceptsPain patternsChronic pancreatitisImaging findingsAbdominal painAbdominal imagingCross-sectional abdominal imagingAbdominal imaging featuresPancreatic ductal dilatationCommon imaging findingsSeverity of painAbdominal imaging findingsEvaluation of patientsPattern of painProspective multicenter studyAbdominal imaging techniquesEndoscopic retrograde cholangiopancreatographyCase report formsClinical research coordinatorsMild painDuctal dilatationPain severitySevere painPatient's painDuctal changesMulticenter study
2011
A Randomized, Double-Blind, Adaptive Phase 2 Multi-Center Study of Prasugrel Compared to Placebo in Adults with Sickle Cell Disease
Wun T, Soulieres D, Krishnamurti L, Kutlar A, Ataga K, Zhou C, Heath L, Nwachuku C, Jakubowski J, Winters K, Riesmeyer J. A Randomized, Double-Blind, Adaptive Phase 2 Multi-Center Study of Prasugrel Compared to Placebo in Adults with Sickle Cell Disease. Blood 2011, 118: 847. DOI: 10.1182/blood.v118.21.847.847.Peer-Reviewed Original ResearchSickle cell diseasePrasugrel armHemorrhagic eventsCell diseaseMedical attentionPain rateAdult patientsPlacebo armPlatelet inhibitionAntiplatelet agentsPharmacodynamic effectsEli LillyP2Y12 ADP receptor antagonistsHemorrhagic adverse eventsInsufficient platelet inhibitionP2Y12 reactivity unitsPrasugrel-treated patientsSerious hemorrhagic eventsADP receptor antagonistsPlatelet reactivity indexAcute coronary syndromeBaseline pain intensityPhase 2 studyPhase 3 studySeverity of pain
2001
Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions.
Friedlaender GE, Perry CR, Cole JD, Cook SD, Cierny G, Muschler GF, Zych GA, Calhoun JH, LaForte AJ, Yin S. Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions. Journal Of Bone And Joint Surgery 2001, 83-A Suppl 1: s151-8. PMID: 11314793, PMCID: PMC1425155, DOI: 10.2106/00004623-200100002-00010.Peer-Reviewed Original ResearchMeSH KeywordsAdultBone Morphogenetic Protein 7Bone Morphogenetic ProteinsBone TransplantationCollagenDrug CarriersDrug Delivery SystemsFemaleFracture Fixation, IntramedullaryFracture HealingFractures, UnunitedHumansMaleProspective StudiesRadiographyRecombinant ProteinsTibial FracturesTransforming Growth Factor betaConceptsTibial nonunionAdverse eventsRadiographic resultsClinical trialsOsteogenic protein-1Bone autograftAutogenous boneChronic donor site painAutograft-treated patientsFresh autogenous bonePlain radiographic evaluationMulti-center clinical trialPercent of patientsSeverity of painDonor site painGroup of patientsProtein 1Bone morphogenetic proteinNumerous animal modelsInvestigational device exemptionDonor site morbiditySame time pointsType ISite painClinical course
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply