A Bimetallic Silver–Neodymium Theranostic Nanoparticle with Multimodal NIR/MRI/CT Imaging and Combined Chemo-photothermal Therapy
Mishra SK, Kannan S. A Bimetallic Silver–Neodymium Theranostic Nanoparticle with Multimodal NIR/MRI/CT Imaging and Combined Chemo-photothermal Therapy. Inorganic Chemistry 2017, 56: 12054-12066. PMID: 28933536, DOI: 10.1021/acs.inorgchem.7b02103.Peer-Reviewed Original ResearchMeSH KeywordsAblation TechniquesAntineoplastic AgentsChitosanContrast MediaDrug CarriersDrug LiberationGreen Chemistry TechnologyHeatingHeLa CellsHumansMagnetic Resonance ImagingMetal NanoparticlesMultimodal ImagingNeodymiumOptical ImagingPaclitaxelParticle SizeSilverTheranostic NanomedicineTomography, X-Ray ComputedConceptsChemo-photothermal therapyPhotothermal effectMicrowave-assisted polyol synthesisCombined chemo-photothermal therapyMRI/CT imagingEfficient photothermal effectHigh loading efficiencyLoading of paclitaxelTheranostic nanoparticlesBimetallic nanoparticlesMetallic nanostructuresGood monodispersityPolyol synthesisNIR laserLoading efficiencyAverage sizeNanoparticlesGood biocompatibilityMultimodal imagingInfrared regionExcellent candidateNIR imagingChitosan functionalizationSynergistic effectDrug molecules