Robert Tseng, MD
Hospital ResidentAbout
Research
Publications
2026
Evolutionarily conserved epigenetic regulation of transcriptional cell states during vertebrate pancreatic tumorigenesis
Matar S, Blázquez-Araguás S, Diéguez-Docampo A, Liu X, Katanga A, Magurk J, Gallien N, Dong M, Lao M, Tezcan N, Tarcan Z, Tseng R, Escobar-Hoyos L, Alonso-Curbelo D, Goodale B, Leach S. Evolutionarily conserved epigenetic regulation of transcriptional cell states during vertebrate pancreatic tumorigenesis. Cellular And Molecular Gastroenterology And Hepatology 2026, 101864. PMID: 42601023, DOI: 10.1016/j.jcmgh.2026.101864.Peer-Reviewed Original ResearchMitochondrial-Localized Keratin 17 Promotes Chemoresistance in Basal-like Pancreatic Cancer
Pan C, Lyu Y, Ghosh M, Siraj A, Tseng R, Chaika N, Haley J, Khalvatifahlylani B, Tuveson D, Patel H, Faruque M, Rajacharya G, Donnelly K, Leiton C, Arbelaez C, Chen H, Chowdhury S, Sarkar S, Coka L, Roa-Peña L, Horowitz M, Marchenko N, Singh P, Shroyer K, Escobar-Hoyos L. Mitochondrial-Localized Keratin 17 Promotes Chemoresistance in Basal-like Pancreatic Cancer. Cancer Research 2026, 86: 2935-2950. PMID: 41817415, PMCID: PMC13266344, DOI: 10.1158/0008-5472.can-25-4534.Peer-Reviewed Original ResearchThis study shows that mitochondrial-localized keratin 17 stabilizes a key enzyme in pyrimidine biosynthesis, driving chemoresistance in pancreatic cancer and identifying a potential therapeutic target.
2023
Morphologic Severity of Atypia Is Predictive of Lung Cancer Diagnosis
Santore L, Novotny S, Tseng R, Patel M, Albano D, Dhamija A, Tannous H, Nemesure B, Shroyer K, Bilfinger T. Morphologic Severity of Atypia Is Predictive of Lung Cancer Diagnosis. Cancers 2023, 15: 397. PMID: 36672346, PMCID: PMC9857279, DOI: 10.3390/cancers15020397.Peer-Reviewed Original Research
2021
Dissecting the Oncogenic Roles of Keratin 17 in the Hallmarks of CancerOncogenic Roles of Keratin 17 in the Hallmarks of Cancer
Baraks G, Tseng R, Pan C, Kasliwal S, Leiton C, Shroyer K, Escobar-Hoyos L. Dissecting the Oncogenic Roles of Keratin 17 in the Hallmarks of CancerOncogenic Roles of Keratin 17 in the Hallmarks of Cancer. Cancer Research 2021, 82: 1159-1166. PMID: 34921015, PMCID: PMC9016724, DOI: 10.1158/0008-5472.can-21-2522.Peer-Reviewed Original Research
2017
Time lapse microscopy of temperature control during self-assembly of 3D DNA crystals
Conn F, Jong M, Tan A, Tseng R, Park E, Ohayon Y, Sha R, Mao C, Seeman N. Time lapse microscopy of temperature control during self-assembly of 3D DNA crystals. Journal Of Crystal Growth 2017, 476: 1-5. DOI: 10.1016/j.jcrysgro.2017.07.019.Peer-Reviewed Original Research