Michael James Boyle
Associate Research Scientist in GeneticsAbout
Research
Publications
2026
A high-coverage Neandertal genome from the Altai Mountains reveals population structure among Neandertals
Massilani D, Peyrégne S, Iasi L, de Filippo C, Mafessoni F, Mesa A, Sümer A, Swiel Y, Popli D, Silverman S, Boyle M, Kozlikin M, Shunkov M, Derevianko A, Higham T, Douka K, Meyer M, Zeberg H, Kelso J, Pääbo S. A high-coverage Neandertal genome from the Altai Mountains reveals population structure among Neandertals. Proceedings Of The National Academy Of Sciences Of The United States Of America 2026, 123: e2534576123. PMID: 41871248, PMCID: PMC13037865, DOI: 10.1073/pnas.2534576123.Peer-Reviewed Original ResearchAncient DNA and Human Physiology
Bayarsaikhan M, Boyle M, Demers P, Habeck E, Romeyer-Dherbey J, Silverman S, Massilani D. Ancient DNA and Human Physiology. Physiology 2026, 41: 000-000. PMID: 41790057, PMCID: PMC13052355, DOI: 10.1152/physiol.00047.2025.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2023
Three linked variants have opposing regulatory effects on isovaleryl-CoA dehydrogenase gene expression
Brown E, Kales S, Boyle M, Vitti J, Kotliar D, Schaffner S, Tewhey R, Sabeti P. Three linked variants have opposing regulatory effects on isovaleryl-CoA dehydrogenase gene expression. Human Molecular Genetics 2023, 33: 270-283. PMID: 37930192, PMCID: PMC10800014, DOI: 10.1093/hmg/ddad177.Peer-Reviewed Original Research
2021
Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases
Fleck J, Sanchís-Calleja F, He Z, Santel M, Boyle M, Camp J, Treutlein B. Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases. Cell Stem Cell 2021, 28: 1177-1180. PMID: 34087154, DOI: 10.1016/j.stem.2021.03.015.Commentaries, Editorials and LettersResolving organoid brain region identities by mapping single-cell genomic data to reference atlases
Fleck J, Sanchís-Calleja F, He Z, Santel M, Boyle M, Camp J, Treutlein B. Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases. Cell Stem Cell 2021, 28: 1148-1159.e8. PMID: 33711282, DOI: 10.1016/j.stem.2021.02.015.Peer-Reviewed Original Research
2019
Organoid single-cell genomic atlas uncovers human-specific features of brain development
Kanton S, Boyle M, He Z, Santel M, Weigert A, Sanchís-Calleja F, Guijarro P, Sidow L, Fleck J, Han D, Qian Z, Heide M, Huttner W, Khaitovich P, Pääbo S, Treutlein B, Camp J. Organoid single-cell genomic atlas uncovers human-specific features of brain development. Nature 2019, 574: 418-422. PMID: 31619793, DOI: 10.1038/s41586-019-1654-9.Commentaries, Editorials and Letters
2017
Detecting ancient positive selection in humans using extended lineage sorting
Peyrégne S, Boyle M, Dannemann M, Prüfer K. Detecting ancient positive selection in humans using extended lineage sorting. Genome Research 2017, 27: 1563-1572. PMID: 28720580, PMCID: PMC5580715, DOI: 10.1101/gr.219493.116.Peer-Reviewed Original Research