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INFORMATION FOR

    Matthew Vesely, MD, PhD

    Assistant Professor of Dermatology
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    About

    Titles

    Assistant Professor of Dermatology

    Biography

    I am a physician-scientist who has trained in immunology, molecular biology, genetics and clinical dermatology. My overall career goal as a physician-scientist are to integrate fundamental immunology with clinical dermatology. In particular, I am interested in the role of costimulatory and inhibitory immune receptors in cancer immunity, autoimmunity pathogenesis and immunotherapy. My interest in this field was driven by my experience in the Medical Scientist Training Program at Washington University in St. Louis, where I worked in the laboratory of Dr. Robert Schreiber to decipher key molecular regulators of cancer immunoediting. As a consequence, the expertise gained in skin immunology and the emerging immunotherapies to treat melanoma inspired me to become a dermatologist. During my dermatology residency, I joined the laboratory of Dr. Lieping Chen at Yale School of Medicine, who pioneered targeting the PD-1 axis for cancer immunotherapy and has discovered multiple novel immune checkpoint molecules including programmed death receptor-1 homolog (PD-1H) (also known as VISTA). My current research interests include: 1) identification of novel immune checkpoints such as PD-1H/VISTA and others in cutaneous malignancies (e.g., melanoma and keratinocyte carcinomas) and 2) elucidating the inhibitory immune landscape of chronic inflammatory disorders such as psoriasis and cutaneous lupus erythematosus.

    Appointments

    Other Departments & Organizations

    Education & Training

    Resident
    Yale School of Medicine (Dermatology) (2014-2017) (2017)
    Intern
    Barnes Jewish Hospital (St. Louis) (2013-2014) (2014)
    PhD
    Washington University School of Medicine, St. Louis, Immunology (2013)
    MD
    Washington University School of Medicine (2013)
    BS
    Creighton University, Biology, Theology, History (2003)

    Research

    Overview

    Medical Research Interests

    Carcinoma, Squamous Cell; Dermatitis; Dermatitis, Atopic; Eczema; Immunoassay; Lichen Planus; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Discoid; Melanoma; Molecular Imaging; Psoriasis; Skin; Skin and Connective Tissue Diseases

    Public Health Interests

    Immunology; Biomarkers; Clinical Trials

    Research at a Glance

    Publications Timeline

    A big-picture view of Matthew Vesely's research output by year.
    54Publications
    6,315Citations

    Publications

    Featured Publications

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    Clinical Care

    Overview

    Matthew Vesely, MD, is a dermatologist who treats psoriasis, eczema, and other autoimmune skin disorders. Dr. Vesely also sees patients with chronic skin diseases, including discoid lupus erythematosus (DLE) and hidradenitis suppurativa (HS).

    “Seeing patients who have been suffering from inflammatory skin diseases for years finally get relief with the help of a targeted therapy is very rewarding,” he says.

    Dr. Vesely says he enjoys working with patients and their families to find the best approach to treat a skin disorder. “I always explain that even if the first set of therapies are ineffective, we won't stop until we find the most effective treatment plan,” he says.

    Dr. Vesely says he chose his specialty after learning that a large number of skin diseases caused by an overactive immune system lack FDA-approved treatments. In his research, Dr. Vesely investigates emerging new therapies that could potentially help his patients.

    “Being able to research the same diseases I treat is extremely gratifying and motivating,” Dr. Vesely says.

    Clinical Specialties

    Dermatology

    Fact Sheets

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    Board Certifications

    • Dermatology

      Certification Organization
      AB of Dermatology
      Original Certification Date
      2017

    Yale Medicine News

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    Academic Achievements & Community Involvement

    • activity

      American Academy of Dermatology

      Professional OrganizationsFellow
    • activity

      Lancet, Nature Cancer, International Journal of Dermatology, Journal of Investigative Dermatology, JAAD Case Reports, Journal of European Academy of Dermatology and Venerology, Frontiers in Oncology, Frontiers in Immunology, Cancers

      Journal ServiceReviewer
    • activity

      Lupus Research Alliance

      Peer Review Groups and Grant Study SectionsGrant Reviewer
    • activity

      Society for Investigative Dermatology

      Professional OrganizationsMember
    • activity

      Medical Dermatology Society

      Professional OrganizationsMember
    See All Achievements

    Get In Touch

    Contacts

    Appointment Number
    Mailing Address

    Dermatology

    333 Cedar Street, LMP 5040, PO Box 208059

    New Haven, CT 06520-8059

    United States

    Administrative Support

    Locations

    • Dermatology

      Academic Office

      Hunter Building

      15 York Street, Rm HRT 603B

      New Haven, CT 06510

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    • Chen Lab

      Lab

      West Campus Molecular Innovations Center

      600 West Campus Drive

      West Haven, CT 06516

      Get Directions

    • Patient Care Locations

      Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.

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    Events

    Jan 20251Wednesday
    Jan 20258Wednesday
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