Src Inhibits Midline Axon Crossing Independent of Frazzled/Deleted in Colorectal Carcinoma (DCC) Receptor Tyrosine Phosphorylation
O'Donnell M, Bashaw G. Src Inhibits Midline Axon Crossing Independent of Frazzled/Deleted in Colorectal Carcinoma (DCC) Receptor Tyrosine Phosphorylation. Journal Of Neuroscience 2013, 33: 305-314. PMID: 23283343, PMCID: PMC3739878, DOI: 10.1523/jneurosci.2756-12.2013.Peer-Reviewed Original ResearchConceptsSrc kinaseMidline axonsTyrosine phosphorylationSrc family kinasesDrosophila embryonic CNSReceptor tyrosine phosphorylationCommissural axonsDrosophila orthologUnexpected functionFamily kinasesEmbryonic CNSDownstream effectorsMidline attractionNetrin receptor DCCKinaseNetrin familyNovel mechanismAttractive turningPhosphorylationEffectorsReceptor DCCOrthologsCommissural neuronsVertebratesFrazzled