Feeding state-dependent regulation of developmental plasticity via CaMKI and neuroendocrine signaling
Neal S, Takeishi A, O'Donnell M, Park J, Hong M, Butcher R, Kim K, Sengupta P. Feeding state-dependent regulation of developmental plasticity via CaMKI and neuroendocrine signaling. ELife 2015, 4: e10110. PMID: 26335407, PMCID: PMC4558564, DOI: 10.7554/elife.10110.Peer-Reviewed Original ResearchConceptsNeuroendocrine signalingDevelopmental plasticityInsulin-like peptide genesDynamic subcellular localizationDauer decisionDauer formationILP genesDauer stageDevelopmental decisionsSubcellular localizationNutrient availabilityState-dependent regulationPeptide genesReproductive cycleUnknown mechanismCaMKICMK-1SignalingGenesSensory neuronsPlasticityExpressionAWCCaenorhabditisSmall neuronal networks