2020
Purpose-Dependent Consequences of Temporal Expectations Serving Perception and Action
van Ede F, Rohenkohl G, Gould I, Nobre A. Purpose-Dependent Consequences of Temporal Expectations Serving Perception and Action. Journal Of Neuroscience 2020, 40: 7877-7886. PMID: 32900836, PMCID: PMC7548698, DOI: 10.1523/jneurosci.1134-20.2020.Peer-Reviewed Original ResearchConceptsTemporal expectationsBrain activityBrain statesFrequency-specific mannerUpcoming perceptionSources of temporal expectationsOscillatory brain activityVisual-motor taskAffected response timesNeurophysiological brain activityBehavioral relevancePerceptual accuracyNeural activityNeural lateralizationNeural statesFemale human volunteersRelevant dimensionsBrainModality-StateTaskHuman volunteersPerceptionResponse speedResponse time
2019
Dissecting beta-state changes during timed movement preparation in Parkinson’s disease
Heideman S, Quinn A, Woolrich M, van Ede F, Nobre A. Dissecting beta-state changes during timed movement preparation in Parkinson’s disease. Progress In Neurobiology 2019, 184: 101731. PMID: 31778771, PMCID: PMC6977086, DOI: 10.1016/j.pneurobio.2019.101731.Peer-Reviewed Original ResearchConcurrent visual and motor selection during visual working memory guided action
van Ede F, Chekroud S, Stokes M, Nobre A. Concurrent visual and motor selection during visual working memory guided action. Nature Neuroscience 2019, 22: 477-483. PMID: 30718904, PMCID: PMC6420070, DOI: 10.1038/s41593-018-0335-6.Peer-Reviewed Original Research
2018
Neural Oscillations: Sustained Rhythms or Transient Burst-Events?
van Ede F, Quinn A, Woolrich M, Nobre A. Neural Oscillations: Sustained Rhythms or Transient Burst-Events? Trends In Neurosciences 2018, 41: 415-417. PMID: 29739627, PMCID: PMC6024376, DOI: 10.1016/j.tins.2018.04.004.Peer-Reviewed Original ResearchImpaired corticomuscular and interhemispheric cortical beta oscillation coupling in amyotrophic lateral sclerosis
Proudfoot M, van Ede F, Quinn A, Colclough G, Wuu J, Talbot K, Benatar M, Woolrich M, Nobre A, Turner M. Impaired corticomuscular and interhemispheric cortical beta oscillation coupling in amyotrophic lateral sclerosis. Clinical Neurophysiology 2018, 129: 1479-1489. PMID: 29678369, DOI: 10.1016/j.clinph.2018.03.019.Peer-Reviewed Original ResearchConceptsALS patientsHealthy controlsCorticomuscular coherenceGene carriersAsymptomatic gene carriersBeta-band corticomuscular coherenceMotor cortexTherapeutic efficacyDisease mimicsMotor system dysfunctionSystem dysfunctionWhole-head magnetoencephalographyPatientsForce productionNeuropathyPrimary motor cortexBeta rhythmsBeta bandCortical hemisphereStructural MRICortexNeural activityMuscular contractionInterhemispheric communicationCorticomuscular
2017
Temporal alignment of anticipatory motor cortical beta lateralisation in hidden visual‐motor sequences
Heideman S, van Ede F, Nobre A. Temporal alignment of anticipatory motor cortical beta lateralisation in hidden visual‐motor sequences. European Journal Of Neuroscience 2017, 48: 2684-2695. PMID: 28921756, PMCID: PMC6220967, DOI: 10.1111/ejn.13700.Peer-Reviewed Original ResearchConceptsSerial reaction timeModified serial reaction timeUpcoming target locationVisual-motor sequencesAnticipatory preparationBehavioral benefitsBrain activityNeural dynamicsBeta oscillationsModulation of motor cortical excitabilityLateralisationSpatial-temporal sequenceMotor cortical excitabilityReaction timeComparing targetsCortical excitabilityTarget location
2016
Altered cortical beta‐band oscillations reflect motor system degeneration in amyotrophic lateral sclerosis
Proudfoot M, Rohenkohl G, Quinn A, Colclough G, Wuu J, Talbot K, Woolrich M, Benatar M, Nobre A, Turner M. Altered cortical beta‐band oscillations reflect motor system degeneration in amyotrophic lateral sclerosis. Human Brain Mapping 2016, 38: 237-254. PMID: 27623516, PMCID: PMC5215611, DOI: 10.1002/hbm.23357.Peer-Reviewed Original ResearchConceptsPrimary lateral sclerosisAmyotrophic lateral sclerosisSensitive marker of disease activityPLS groupMotor cortex of ALS patientsBeta-band oscillationsMarkers of disease activityDevelopment of overt symptomsHealthy control groupALS spectrumAmyotrophic lateral sclerosis patientsAsymptomatic mutation carriersDiffusion tensor imaging studiesBeta desynchronizationSymptomatic patientsLateral sclerosisDisease activityMutation carriersGene mutationsCortical hyperexcitabilityAsymptomatic carriersSensitive markerNeuroprotective strategiesImaging studiesCortical dysfunctionBehavioral and Neural Markers of Flexible Attention over Working Memory in Aging
Mok R, Myers N, Wallis G, Nobre A. Behavioral and Neural Markers of Flexible Attention over Working Memory in Aging. Cerebral Cortex 2016, 26: 1831-1842. PMID: 26865653, PMCID: PMC4785959, DOI: 10.1093/cercor/bhw011.Peer-Reviewed Original ResearchConceptsRetro-cueWorking memoryOlder adultsMeasured magnetoencephalographyHigher order cognitionPerformance of older adultsOrienting of attentionWM performanceCueing benefitsWM maintenanceWM representationsMitigate cognitive declineFlexible attentionMemory precisionAttentional benefitsNeural markersOscillatory powerCognitive declineNeural dynamicsMEG recordingsMemoryHealthy agingPreservation of controllabilityRelevant itemsModel-based analysis
2012
Effects of Decision Variables and Intraparietal Stimulation on Sensorimotor Oscillatory Activity in the Human Brain
Gould I, Nobre A, Wyart V, Rushworth M. Effects of Decision Variables and Intraparietal Stimulation on Sensorimotor Oscillatory Activity in the Human Brain. Journal Of Neuroscience 2012, 32: 13805-13818. PMID: 23035092, PMCID: PMC3491879, DOI: 10.1523/jneurosci.2200-12.2012.Peer-Reviewed Original ResearchConceptsProbabilistic reasoning tasksParticipants integrated informationBeta band activityCue processingCue stimulusIntraparietal sulcusReasoning tasksSensorimotor cortexOscillatory activityCuesHuman brainMotor cortexUpdate signalCortexSensorimotorExecution choicesBeta bandSensorimotor oscillatory activityDecision makingBrainObservation cuesSulcusStimuliTaskLateralization