2024
Neural dynamics of shifting attention between perception and working-memory contents
Gresch D, Boettcher S, Gohil C, van Ede F, Nobre A. Neural dynamics of shifting attention between perception and working-memory contents. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2406061121. PMID: 39536078, PMCID: PMC11588118, DOI: 10.1073/pnas.2406061121.Peer-Reviewed Original ResearchConceptsAttention shiftsBrain activityNeural dynamicsPatterns of human brain activityWorking-memory taskWorking-memory contentsVisual contentInternal memory representationsWorking memoryMemory representationsSequential cuesHuman brain activityMultivariate decodingAlpha lateralizationSpatial attentionNeural statesCuesSensory environmentEveryday tasksTaskPerceptionCombined perceptionAttentionAlternative domainsMagnetoencephalographyShifting attention between perception and working memory
Gresch D, Boettcher S, van Ede F, Nobre A. Shifting attention between perception and working memory. Cognition 2024, 245: 105731. PMID: 38278040, DOI: 10.1016/j.cognition.2024.105731.Peer-Reviewed Original ResearchConceptsWorking memoryExperiment 1Working-memory taskShifts of attentionStay trialsAttentional orientingAttention domainEveryday cognitionAttention shiftsExperiment 2Shift trialsSpatial attentionAdaptive behaviorBaseline conditionsMemoryEveryday tasksSensory stimulationSensory signalsParticipantsTaskItemsPerceptionCognitionAttentionInternal domain
2022
Functional but not obligatory link between microsaccades and neural modulation by covert spatial attention
Liu B, Nobre A, van Ede F. Functional but not obligatory link between microsaccades and neural modulation by covert spatial attention. Nature Communications 2022, 13: 3503. PMID: 35715471, PMCID: PMC9205986, DOI: 10.1038/s41467-022-31217-3.Peer-Reviewed Original ResearchConceptsCompared to trialsSpatial attentionCovert spatial attentionModulation of alpha activityVisual working memoryModulation of neural activitySpatial modulationNeural modulationEEG alpha activityAlpha activityWorking memoryNeural signaturesNeural activityDirectional biasMemorised locationEye movementsFixational eye movementsMicrosaccades
2019
Human gaze tracks attentional focusing in memorized visual space
van Ede F, Chekroud S, Nobre A. Human gaze tracks attentional focusing in memorized visual space. Nature Human Behaviour 2019, 3: 462-470. PMID: 31089296, PMCID: PMC6546593, DOI: 10.1038/s41562-019-0549-y.Peer-Reviewed Original Research
2017
Differences between endogenous attention to spatial locations and sensory modalities
Vibell J, Klinge C, Zampini M, Nobre A, Spence C. Differences between endogenous attention to spatial locations and sensory modalities. Experimental Brain Research 2017, 235: 2983-2996. PMID: 28717820, PMCID: PMC5603640, DOI: 10.1007/s00221-017-5030-4.Peer-Reviewed Original ResearchConceptsSensory modalitiesSpatial attentionTemporal-order judgment taskModulate perceptual processingJudgment taskPerceptual processingNeural mechanismsTemporal discriminationSpatial locationEndogenous attentionP1 potentialNeural activityLatency effectsAttention moduleLatencyAttentionExperimental designPreparatory α-band oscillations reflect spatial gating independently of predictions regarding target identity
Wildegger T, van Ede F, Woolrich M, Gillebert C, Nobre A. Preparatory α-band oscillations reflect spatial gating independently of predictions regarding target identity. Journal Of Neurophysiology 2017, 117: 1385-1394. PMID: 28077669, PMCID: PMC5350265, DOI: 10.1152/jn.00856.2016.Peer-Reviewed Original ResearchConceptsSpatial gatingGating of informationAttentional cuesHuman brain oscillationsTarget identityFeature-based predictionsCue-target intervalVisual targetVisual detection taskFeature-based attentionUpcoming visual targetSpatial attention cuesCovert spatial attentionOscillationsUninformative cuesBehavioral benefitsBrain activityBehavioral levelAnticipatory attentionCortical regionsSpatial attentionA-bandAttended locationSpatial cuesBrain oscillations
2016
Retrospective Attention Interacts with Stimulus Strength to Shape Working Memory Performance
Wildegger T, Humphreys G, Nobre A. Retrospective Attention Interacts with Stimulus Strength to Shape Working Memory Performance. PLOS ONE 2016, 11: e0164174. PMID: 27706240, PMCID: PMC5051714, DOI: 10.1371/journal.pone.0164174.Peer-Reviewed Original ResearchConceptsWorking memoryWM performanceExperiment 2Working memory performanceRetrospective attentionWM taskWM maintenanceWM representationsStimulus contrastOrienting attentionHigh-contrast stimuliMemory performanceExperiment 3Perceptual representationsExperiment 1RetrocueLow-contrast stimuliSpatial attentionInfluence performanceStimuliSub-threshold stimuliMixture-model approachRetrospective orientationStimulus strengthEncodingApolipoprotein ɛ4 breaks the association between declarative long-term memory and memory-based orienting of spatial attention in middle-aged individuals
Salvato G, Patai E, McCloud T, Nobre A. Apolipoprotein ɛ4 breaks the association between declarative long-term memory and memory-based orienting of spatial attention in middle-aged individuals. Cortex 2016, 82: 206-216. PMID: 27395443, PMCID: PMC4981431, DOI: 10.1016/j.cortex.2016.06.002.Peer-Reviewed Original ResearchConceptsDeclarative long-term memoryOrienting of spatial attentionLong-term memoryApo E4 genotypeSpatial attentionModulates declarative memoryMiddle-aged individualsVisuo-spatial attentionIdentification of cognitive dysfunctionAlzheimer's diseaseE4 genotypeDeclarative memoryExplicit memoryMemory deficitsAttention taskE4 carriersGrowing body of studiesCognitive dysfunctionBrain agingLate-onset Alzheimer's diseaseBody of studiesMemory systemAPOE e4 carriersBrain occurringMemory
2011
Orienting attention to locations in mental representations
Astle D, Summerfield J, Griffin I, Nobre A. Orienting attention to locations in mental representations. Attention, Perception, & Psychophysics 2011, 74: 146-162. PMID: 21972046, PMCID: PMC4152722, DOI: 10.3758/s13414-011-0218-3.Peer-Reviewed Original ResearchConceptsVisual short-term memoryVSTM representationsVisual short-term memory capacityContents of visual short-term memoryTop-down attentional biasesSpatial cuesInvalid spatial cuesTop-down biasRetro-cueAttentional biasUncued itemsMemory searchOrienting attentionMemory loadUnattended itemsCue delayShort-term memoryCognitive processesIconic memoryMental representationsSpatial attentionCuesMemorySensory inputItemsAlpha Oscillations Related to Anticipatory Attention Follow Temporal Expectations
Rohenkohl G, Nobre A. Alpha Oscillations Related to Anticipatory Attention Follow Temporal Expectations. Journal Of Neuroscience 2011, 31: 14076-14084. PMID: 21976492, PMCID: PMC4235253, DOI: 10.1523/jneurosci.3387-11.2011.Peer-Reviewed Original ResearchConceptsTemporal expectationsAlpha-band activityTarget stimuliOscillatory alpha-band activityAlpha desynchronizationCortical excitabilityRegulate cortical excitabilityEvent-related potentialsRegulate excitabilityTask-relevant eventsOscillatory brain activityExcitationPerceptual discriminationOcclusion periodBrain activitySpatial attentionSpatial expectationsAlpha oscillationsEnhancement of processesTime courseBandOccluding bandAlpha bandVisual areasOscillationsModulation of neural activity by motivational and spatial biases
Baines S, Ruz M, Rao A, Denison R, Nobre A. Modulation of neural activity by motivational and spatial biases. Neuropsychologia 2011, 49: 2489-2497. PMID: 21570417, DOI: 10.1016/j.neuropsychologia.2011.04.029.Peer-Reviewed Original ResearchConceptsEvent-related potentialsLateralised readiness potentialNeural activityCognitive processesTime course of information processingCourse of information processingInfluence behavioral performanceLate cognitive processesNon-rewarding stimuliModulation of neural activityAnalysis of stimuliP300-like potentialsReaction timeModulate neural activityReward trialsPosner taskCue stimulusEffect of motivationMotivational biasesBehavioral performanceTarget stimuliStimulus representationsReadiness potentialSpatial attentionSpatial expectationsMarkers of preparatory attention predict visual short-term memory performance
Murray A, Nobre A, Stokes M. Markers of preparatory attention predict visual short-term memory performance. Neuropsychologia 2011, 49: 1458-1465. PMID: 21335015, PMCID: PMC3318119, DOI: 10.1016/j.neuropsychologia.2011.02.016.Peer-Reviewed Original ResearchConceptsCue-related changesContralateral delay activityPreparatory attentionVisual short-term memoryMemory-based performancePreparatory brain activityEncoded itemsEncoding taskProbe itemERP markersMemory representationsMemory loadMemory recallShort-term memoryAccurate memory recallBrain activityRecall probabilityRecall accuracySpatial attentionAttention positivityPrecision of recallSpatial cuesBehavioral dataEarly attentionDelayed activationBehavioural Dissociation between Exogenous and Endogenous Temporal Orienting of Attention
Rohenkohl G, Coull J, Nobre A. Behavioural Dissociation between Exogenous and Endogenous Temporal Orienting of Attention. PLOS ONE 2011, 6: e14620. PMID: 21297968, PMCID: PMC3030556, DOI: 10.1371/journal.pone.0014620.Peer-Reviewed Original ResearchConceptsSymbolic cuesTemporal orientationEffect of temporal orientationTemporal orienting of attentionSpeeded reaction timesStrategic controlOrienting of attentionNeutral trialsBehavioral dissociationCueing effectsEndogenous orientingPerceptual discriminationTemporal expectationsIntrinsic temporal structureSpatial attentionOccluding bandCuesRhythmic cuesTask designReaction timeTemporal structureMoving stimuliPredictive natureTaskParticipants
2010
Purely endogenous capture of attention by task-defining features proceeds independently from spatial attention
Brignani D, Lepsien J, Nobre A. Purely endogenous capture of attention by task-defining features proceeds independently from spatial attention. NeuroImage 2010, 51: 859-866. PMID: 20302948, DOI: 10.1016/j.neuroimage.2010.03.029.Peer-Reviewed Original ResearchConceptsEvent-related-potentialsUnattended locationsSpatial attentionSpatial biasSpatial attentional biasTask-relevant eventsTop-down spatial attentionAttentional biasAttentional captureSalient stimuliTask goalsUnattended targetsAttention AttentionStimuliAppearance of stimuliSpatial locationCapture mechanismSubliminally Presented and Stored Objects Capture Spatial Attention
Astle D, Nobre A, Scerif G. Subliminally Presented and Stored Objects Capture Spatial Attention. Journal Of Neuroscience 2010, 30: 3567-3571. PMID: 20219990, PMCID: PMC6632246, DOI: 10.1523/jneurosci.5701-09.2010.Peer-Reviewed Original Research
2009
The Timing of Neural Activity during Shifts of Spatial Attention
Brignani D, Lepsien J, Rushworth M, Nobre A. The Timing of Neural Activity during Shifts of Spatial Attention. Journal Of Cognitive Neuroscience 2009, 21: 2369-2383. PMID: 19199414, DOI: 10.1162/jocn.2008.21176.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalysis of VarianceAttentionBrain MappingColor PerceptionCuesElectroencephalographyElectrooculographyEvoked Potentials, VisualFemaleFixation, OcularFunctional LateralityHumansMaleMiddle AgedPhotic StimulationReaction TimeSignal Detection, PsychologicalSpace PerceptionTime FactorsYoung AdultConceptsShifts of spatial attentionEvent-related potentialsTiming of neural activitySpatial attentionNeural activityScalp regionsOvert shifts of spatial attentionDivided-attention conditionPosterior scalp regionsFrontal scalp regionsPosterior parietal areasFocused-attention conditionExperiments compared performanceFocused-attention taskOvert shiftsVisual lettersTarget stimuliColored lettersExperimental tasksParietal areasSpatial cuesBehavioral experimentsCovert versionSpatial shiftTask
2008
Choosing Where to Attend and the Medial Frontal Cortex: An fMRI Study
Taylor P, Rushworth M, Nobre A. Choosing Where to Attend and the Medial Frontal Cortex: An fMRI Study. Journal Of Neurophysiology 2008, 100: 1397-1406. PMID: 18596189, PMCID: PMC2544456, DOI: 10.1152/jn.90241.2008.Peer-Reviewed Original ResearchConceptsAttention conditionMedial frontal cortical regionsEye fieldLateral frontal eye fieldsMedial frontal cortexFrontal cortical regionsFunctional magnetic resonancePeripheral spatial locationsVisual detection taskFrontal eye fieldMemory confoundsAttentional orientingFree selectionFMRI studyCentral cuesFrontal cortexOvert actionsCortical regionsCovert attentionSpatial attentionNeural activityChoice trialsVoluntary attentionDetection taskMemory
2006
Selective Attention to Specific Features within Objects: Behavioral and Electrophysiological Evidence
Nobre A, Rao A, Chelazzi L. Selective Attention to Specific Features within Objects: Behavioral and Electrophysiological Evidence. Journal Of Cognitive Neuroscience 2006, 18: 539-561. PMID: 16768359, DOI: 10.1162/jocn.2006.18.4.539.Peer-Reviewed Original ResearchConceptsBidimensional stimuliUnidimensional stimuliInhibition of irrelevant featuresModulation of brain activityEvent-related potentialsDimensions of attentionIdentical physical stimuliNegative primingSelective attentionNeural processesBehavioral resultsAttentional effectsBrain activityTask performanceSpatial attentionPerceptual analysisUnpredictable orderElectrophysiological evidenceTask informationDominant dimensionStimuliNeural modulationParticipantsRelevant responsesElectrophysiological effectsOrienting Attention Based on Long-Term Memory Experience
Summerfield J, Lepsien J, Gitelman D, Mesulam M, Nobre A. Orienting Attention Based on Long-Term Memory Experience. Neuron 2006, 49: 905-916. PMID: 16543137, DOI: 10.1016/j.neuron.2006.01.021.Peer-Reviewed Original ResearchConceptsMemory-guided attentionEvent-related functional magnetic resonance imagingSpatial attentionFunctional magnetic resonance imagingRetrieval of memoryVisual spatial orientingMemory of objectsLong-term memoryParietal-frontal networkAttention-orienting taskAttentional orientingOrienting attentionBehavioral effectsNaturalistic scenesBehavioral advantageMemory experimentsBrain areasDetection of objectsPerceptual domainNeural systemsExperimental paradigmSpatial cuesStable memorySpatial orientationComplex scenesFEF TMS Affects Visual Cortical Activity
Taylor P, Nobre A, Rushworth M. FEF TMS Affects Visual Cortical Activity. Cerebral Cortex 2006, 17: 391-399. PMID: 16525126, DOI: 10.1093/cercor/bhj156.Peer-Reviewed Original ResearchConceptsFEF TMSTMS-induced effectsEvent-related potentialsFrontal eye fieldTranscranial magnetic stimulationModulation of visual activityHuman frontal eye fieldRight frontal eye fieldVisual cortical activityVisual stimuliNeural activityOrienting of spatial attentionVisual event-related potentialsVisual brain areasCovert attention taskCue periodAttention taskBrain areasBrain activityPosterior electrodesSpatial attentionEye fieldVisual processingVisual attentionMagnetic stimulation