2023
Time for Memories
Buonomano D, Buzsáki G, Davachi L, Nobre A. Time for Memories. Journal Of Neuroscience 2023, 43: 7565-7574. PMID: 37940593, PMCID: PMC10634580, DOI: 10.1523/jneurosci.1430-23.2023.Peer-Reviewed Original ResearchConceptsWorking memoryEpisodic memoryNeural mechanismsInfluence of episodic memoryProcess temporal informationBrain storesTemporal cognitionCognitive functionAdaptive behaviorTemporal anticipationMemoryNeural sequencesBrainSpatiotemporal codingTemporal structureComputational motifsCognitionTemporal informationRecallAnticipationEpisodesPerception
2020
One Thing Leads to Another: Anticipating Visual Object Identity Based on Associative-Memory Templates
Boettcher S, Stokes M, Nobre A, van Ede F. One Thing Leads to Another: Anticipating Visual Object Identity Based on Associative-Memory Templates. Journal Of Neuroscience 2020, 40: 4010-4020. PMID: 32284338, PMCID: PMC7219293, DOI: 10.1523/jneurosci.2751-19.2020.Peer-Reviewed Original ResearchConceptsContingent negative variationTemporal anticipationElectrophysiological signaturesMemory templatesProbabilistic associationsNegative variationAnticipatory mechanismsAlpha oscillationsAlpha-band oscillationsField of attentionAttentional templatesMemory cuesNeural substratesPreparatory attentionTask-relevantExperiment 2Neural mechanismsBehavioral consequencesBehavioral benefitsObject identityMotor responsePerceptual identityElectrophysiological substrateHuman electrophysiologyAnticipatory states
2018
Not All Predictions Are Equal: “What” and “When” Predictions Modulate Activity in Auditory Cortex through Different Mechanisms
Auksztulewicz R, Schwiedrzik C, Thesen T, Doyle W, Devinsky O, Nobre A, Schroeder C, Friston K, Melloni L. Not All Predictions Are Equal: “What” and “When” Predictions Modulate Activity in Auditory Cortex through Different Mechanisms. Journal Of Neuroscience 2018, 38: 8680-8693. PMID: 30143578, PMCID: PMC6170983, DOI: 10.1523/jneurosci.0369-18.2018.Peer-Reviewed Original ResearchConceptsNeural mechanismsNeural processesMotor areaSensory processingCortical activitySuperior temporal gyrusShort-term plasticityTiming of acoustic eventsAuditory areasMechanisms of predictionPrefrontal regionsPrefrontal areasTemporal gyrusBrain regionsManipulated predictionNeural responsesStimulus attributesStimulus featuresEncode predictionsParticipants' predictionsAdaptive behaviorEnvironmental regularitiesNeurophysiological mechanismsCortical hierarchyExperimental manipulationEncoding-related brain activity and accelerated forgetting in transient epileptic amnesia
Atherton K, Filippini N, Zeman A, Nobre A, Butler C. Encoding-related brain activity and accelerated forgetting in transient epileptic amnesia. Cortex 2018, 110: 127-140. PMID: 29861041, PMCID: PMC6335262, DOI: 10.1016/j.cortex.2018.04.015.Peer-Reviewed Original ResearchConceptsTransient epileptic amnesiaAccelerated forgettingMemory tracesBrain activityEpileptic amnesiaSyndrome of transient epileptic amnesiaEncoding-related activityAnterograde memory tasksFunctional MRI scansEncoding of memoriesVulnerable to interferenceMemory taskBrain systemsRecognition memoryHippocampal activityMemory paradigmRetention intervalMemory impairmentNeural mechanismsPoor memoryAbnormal encodingReduced deactivationWord listsHealthy control subjectsNormal performanceP.4.003 Mood instability and reward processing: daily remote monitoring as a modern phenotyping tool for bipolar disorder
Panchal P, Scholl J, Nelissen N, Saunders K, Darby D, Rushworth M, Harrison P, Nobre A, Harmer C. P.4.003 Mood instability and reward processing: daily remote monitoring as a modern phenotyping tool for bipolar disorder. European Neuropsychopharmacology 2018, 28: s88-s89. DOI: 10.1016/j.euroneuro.2017.12.121.Peer-Reviewed Original ResearchMood Disorder QuestionnaireMood instabilityBipolar disorderRisk-taking behaviorGambling TaskAffect scoresReward processing tasksMonitoring of cognitionPANAS positive affectNegative affect scoresPositive affect scoresCognitive task dataPerception of rewardReward processingAffective disordersPositive affectCognitive underpinningsGambling optionsAssociated cognitionsNeural mechanismsRisky choiceCognitive processesInduce risk-taking behaviorsCognitive monitoringMood monitoring
2017
Anticipated moments: temporal structure in attention
Nobre A, van Ede F. Anticipated moments: temporal structure in attention. Nature Reviews Neuroscience 2017, 19: 34-48. PMID: 29213134, DOI: 10.1038/nrn.2017.141.Peer-Reviewed Original ResearchConceptsTemporal expectationsObject-based attentionDomains of perceptionFeature-based expectationRelevant sensory inputAttentional biasCue associationsCognitive domainsNeural mechanismsNeural responsesCognitive disordersSynchrony of neuronal activityTemporal structureNeuronal activityTemporal attentionSensory inputFeature-basedPointsAttentionRelevant momentsAttentionPerceptionExpectationsDisordersTemporal Anticipation Based on Memory
Cravo A, Rohenkohl G, Santos K, Nobre A. Temporal Anticipation Based on Memory. Journal Of Cognitive Neuroscience 2017, 29: 2081-2089. PMID: 28777060, PMCID: PMC5884434, DOI: 10.1162/jocn_a_01172.Peer-Reviewed Original ResearchConceptsLearned temporal associationsLong-term memoryInfluence of long-term memoryAssociative memoryTarget appearanceTime of target appearanceEcological roleDiscrimination of targetsNeural mechanismsRetroactive functionTemporal predictionTemporal preparationNeural markersTemporal associationTemporal contingencyTemporal anticipationDynamic natureMemoryDifferences between endogenous attention to spatial locations and sensory modalities
Vibell J, Klinge C, Zampini M, Nobre A, Spence C. Differences between endogenous attention to spatial locations and sensory modalities. Experimental Brain Research 2017, 235: 2983-2996. PMID: 28717820, PMCID: PMC5603640, DOI: 10.1007/s00221-017-5030-4.Peer-Reviewed Original ResearchConceptsSensory modalitiesSpatial attentionTemporal-order judgment taskModulate perceptual processingJudgment taskPerceptual processingNeural mechanismsTemporal discriminationSpatial locationEndogenous attentionP1 potentialNeural activityLatency effectsAttention moduleLatencyAttentionExperimental designTemporal Expectations Guide Dynamic Prioritization in Visual Working Memory through Attenuated α Oscillations
van Ede F, Niklaus M, Nobre A. Temporal Expectations Guide Dynamic Prioritization in Visual Working Memory through Attenuated α Oscillations. Journal Of Neuroscience 2017, 37: 437-445. DOI: 10.1523/jneurosci.2272-16.2017.Peer-Reviewed Original ResearchVisual working memoryWorking memoryTemporal expectationsAttentional prioritizationNeural substratesBrain areasStudies of working memoryFlexible goal-directed behaviorMemory retrieval timeInvestigate working memoryWorking memory performanceGoal-directed behaviorEcologically valid contextInvestigated visual working memorySensory brain areasVisual brain areasMemory performanceLaboratory tasksNeuronal underpinningsMental representationsNeural mechanismsDelay intervalNeural implementationValid contextsPrecision judgments
2016
Temporal Expectations Guide Dynamic Prioritization in Visual Working Memory through Attenuated α Oscillations
van Ede F, Niklaus M, Nobre A. Temporal Expectations Guide Dynamic Prioritization in Visual Working Memory through Attenuated α Oscillations. Journal Of Neuroscience 2016, 37: 437-445. PMID: 28077721, PMCID: PMC5242399, DOI: 10.1523/jneurosci.2272-16.2016.Peer-Reviewed Original ResearchConceptsVisual working memoryWorking memoryTemporal expectationsAttentional prioritizationNeural substratesBrain areasStudies of working memoryFlexible goal-directed behaviorMemory retrieval timeInvestigate working memoryWorking memory performanceGoal-directed behaviorEcologically valid contextInvestigated visual working memorySensory brain areasVisual brain areasMemory performanceLaboratory tasksNeuronal underpinningsMental representationsNeural mechanismsDelay intervalNeural implementationValid contextsPrecision judgments
2015
ERP markers of target selection discriminate children with high vs. low working memory capacity
Shimi A, Nobre A, Scerif G. ERP markers of target selection discriminate children with high vs. low working memory capacity. Frontiers In Systems Neuroscience 2015, 9: 153. PMID: 26594157, PMCID: PMC4633470, DOI: 10.3389/fnsys.2015.00153.Peer-Reviewed Original ResearchVisual working memoryVisual working memory performanceCueing benefitsVWM capacityNeural mechanismsSelective attentionVisual working memory capacityChildren's neural activationPosterior scalp locationsTen-year-oldsArrow cuesERP markersWorking memoryContralateral negativityAttentional selectionBehavioral performanceTemporal dynamics of selectionColored itemsN2pcNeural activityChildren's selectionScalp locationsVisual perceptionRecognition phaseAdult selection
2013
Distinct neural mechanisms of individual and developmental differences in VSTM capacity
Astle D, Harvey H, Stokes M, Mohseni H, Nobre A, Scerif G. Distinct neural mechanisms of individual and developmental differences in VSTM capacity. Developmental Psychobiology 2013, 56: 601-610. PMID: 23775219, DOI: 10.1002/dev.21126.Peer-Reviewed Original Research
2011
Top-down modulation: bridging selective attention and working memory
Gazzaley A, Nobre A. Top-down modulation: bridging selective attention and working memory. Trends In Cognitive Sciences 2011, 16: 129-135. PMID: 22209601, PMCID: PMC3510782, DOI: 10.1016/j.tics.2011.11.014.Peer-Reviewed Original ResearchConceptsTop-down modulationSource of top-down signalsMaintenance of relevant informationParietal control regionsInfluence working memoryHuman neurophysiological studiesEncoding of stimuliTop-down signalsWM taskMemory retrievalWorking memoryCognitive operationsNeural mechanismsSelective attentionCognitive resourcesReview recent evidenceStimulus-presentCore featuresSensory cortexNeurophysiological studiesConcurrent engagementMemoryRecent evidenceStimuliActivity modulationLong-term memory prepares neural activity for perception
Stokes M, Atherton K, Patai E, Nobre A. Long-term memory prepares neural activity for perception. Proceedings Of The National Academy Of Sciences Of The United States Of America 2011, 109: e360-e367. PMID: 22109554, PMCID: PMC3277524, DOI: 10.1073/pnas.1108555108.Peer-Reviewed Original ResearchConceptsContents of long-term memoryLong-term memoryMemory-guided attentionDorsal frontoparietal circuitFunctional MRI resultsVisual cortexExtrastriate visual cortexAlpha-band activityAttentional orientingPerceptual processingFrontoparietal circuitsOngoing perceptionNeural mechanismsPerceptual sensitivitySource of predictive informationFunctional MRINeural activityPreparatory stateCortical networksBrain statesCortexPreparatory activityPast experiencesMemorySpatial locationAge-Related Changes in Orienting Attention in Time
Zanto T, Pan P, Liu H, Bollinger J, Nobre A, Gazzaley A. Age-Related Changes in Orienting Attention in Time. Journal Of Neuroscience 2011, 31: 12461-12470. PMID: 21880908, PMCID: PMC3205974, DOI: 10.1523/jneurosci.1149-11.2011.Peer-Reviewed Original ResearchConceptsTemporal cuesOlder adultsNormal agingYoung adultsContingent negative variationTask complexityAlpha-band activityOrienting attentionAttentional resourcesBehavioral performanceNeural mechanismsAge-related changesNegative variationBand activityCuesExpectancy deficitElectroencephalographic dataDeficitsAdultsTaskResponse timeAttentionPrestimulusRelevant pointsEnhanced performanceResponse inhibition results in the emotional devaluation of faces: neural correlates as revealed by fMRI
Doallo S, Raymond J, Shapiro K, Kiss M, Eimer M, Nobre A. Response inhibition results in the emotional devaluation of faces: neural correlates as revealed by fMRI. Social Cognitive And Affective Neuroscience 2011, 7: 649-659. PMID: 21642353, PMCID: PMC3427860, DOI: 10.1093/scan/nsr031.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingResponse inhibitionNeural mechanismsBrain activityTop-down inhibitory mechanismsSocial Emotional EvaluationResponse to facesSocial-emotional networkGo/No-Go taskTask 2TASK-1Amygdala activationExecutive controlResponse-selectionBehavioral ratingsGo/No-GoInhibitory controlBrain mechanismsRating taskBehavioral measuresBrain areasResponse suppressionAffective responsesValue representationMagnetic resonance imagingIndexing the graded allocation of visuospatial attention using anticipatory alpha oscillations
Gould I, Rushworth M, Nobre A. Indexing the graded allocation of visuospatial attention using anticipatory alpha oscillations. Journal Of Neurophysiology 2011, 105: 1318-1326. PMID: 21228304, PMCID: PMC3074422, DOI: 10.1152/jn.00653.2010.Peer-Reviewed Original ResearchConceptsAllocation of visuospatial attentionVisuospatial attentionAssociated with response preparationEvent-related potential measuresPredictive of behavioral performanceTime-frequency analysis of EEG dataSpatial certaintyAlpha oscillationsLateralization of alpha-band activityCue-target intervalProcessing of targetsTop-down controlAlpha-band activityAnalysis of EEG dataAttentional goalsBehavioral performanceResponse preparationOccipitoparietal cortexNeural mechanismsAlpha lateralizationAlpha modulationReaction timeBeta bandLateralizationEEG data
2009
Applying an Attentional Set to Perceived and Remembered Features
Astle D, Nobre A, Scerif G. Applying an Attentional Set to Perceived and Remembered Features. PLOS ONE 2009, 4: e7613. PMID: 19898613, PMCID: PMC2764142, DOI: 10.1371/journal.pone.0007613.Peer-Reviewed Original ResearchConceptsVisual short-term memoryEvent-related brain potentialsGlobal field powerAttentional setStimulus featuresGlobal field power differencesStay trialsBrain potentialsTrial typesNeural mechanismsShort-term memoryNeural generatorsPerceptual objectsPrevious researchQualitatively different configurationsFeatures of objectsField powerControl processAmplitude differencesTopographic differencesPerformance costParticipantsStimuliTrialsMemorySearching for Targets within the Spatial Layout of Visual Short-Term Memory
Kuo B, Rao A, Lepsien J, Nobre A. Searching for Targets within the Spatial Layout of Visual Short-Term Memory. Journal Of Neuroscience 2009, 29: 8032-8038. PMID: 19553443, PMCID: PMC6666054, DOI: 10.1523/jneurosci.0952-09.2009.Peer-Reviewed Original ResearchConceptsVisual short-term memoryVSTM representationsTarget itemsNeural mechanismsShort-term memoryTask goalsVisual search arrayEvent-related potentialsPerceptual arraysScalp distributionPerceptual domainVisual searchNeural activityInternal representationDegree of overlapItemsMemoryTarget objectTaskTarget selectionN2pcN2pcsSpatial layoutRepresentationFindings
2008
Spatial attention can bias search in visual short-term memory
Nobre A, Griffin I, Rao A. Spatial attention can bias search in visual short-term memory. Frontiers In Human Neuroscience 2008, 2: 4. PMID: 18958218, PMCID: PMC2525979, DOI: 10.3389/neuro.09.004.2007.Peer-Reviewed Original ResearchVisual short-term memoryEvent-related potentialsSpatial retro-cueRetro-cueShort-term memoryBehavioral resultsProbe stimuliAssociated with visual short-term memoryVisual short-term memory loadLevels of stimulus analysisTop-down attentional controlTop-down attentional biasesEvent-related potential componentNeutral retro-cuesRetro-cue trialsMemory-related functionsAttentional biasProbe itemAttentional controlOrienting attentionStimulus analysisMnemonic functionsBehavioral measuresNeural mechanismsColored items