Short-term memory advantage for brief durations in human APOE ε4 carriers
Zokaei N, Grogan J, Fallon S, Slavkova E, Hadida J, Manohar S, Nobre A, Husain M. Short-term memory advantage for brief durations in human APOE ε4 carriers. Scientific Reports 2020, 10: 9503. PMID: 32528115, PMCID: PMC7289888, DOI: 10.1038/s41598-020-66114-6.Peer-Reviewed Original ResearchConceptsApolipoprotein E4 geneE4 geneAntagonistic pleiotropy effectsAlzheimer's diseaseE4 alleleGenetic risk factorsGene poolDeleterious genesAntagonistic pleiotropyShort-term memoryGenetic variantsApolipoprotein E4 alleleEvolutionary biologyGene allelesGenesMemory advantagePleiotropic effectsAllelesPleiotropy effectsNon-carriersShort-term memory performanceAPOE e4 carriersSignificant memory advantageHuman populationHuman cognitive functions