2020
Short-term memory advantage for brief durations in human APOE ε4 carriers
Zokaei N, Grogan J, Fallon S, Slavkova E, Hadida J, Manohar S, Nobre A, Husain M. Short-term memory advantage for brief durations in human APOE ε4 carriers. Scientific Reports 2020, 10: 9503. PMID: 32528115, PMCID: PMC7289888, DOI: 10.1038/s41598-020-66114-6.Peer-Reviewed Original ResearchConceptsApolipoprotein E4 geneE4 geneAntagonistic pleiotropy effectsAlzheimer's diseaseE4 alleleGenetic risk factorsGene poolDeleterious genesAntagonistic pleiotropyShort-term memoryGenetic variantsApolipoprotein E4 alleleEvolutionary biologyGene allelesGenesMemory advantagePleiotropic effectsAllelesPleiotropy effectsNon-carriersShort-term memory performanceAPOE e4 carriersSignificant memory advantageHuman populationHuman cognitive functions
2018
Dissociable effects of the apolipoprotein-E (APOE) gene on short- and long-term memories
Zokaei N, Čepukaitytė G, Board A, Mackay C, Husain M, Nobre A. Dissociable effects of the apolipoprotein-E (APOE) gene on short- and long-term memories. Neurobiology Of Aging 2018, 73: 115-122. PMID: 30342272, PMCID: PMC6261846, DOI: 10.1016/j.neurobiolaging.2018.09.017.Peer-Reviewed Original ResearchConceptsLong-term memoryFunction of apolipoproteinsLong-term memory impairmentLong-term memory performanceMeasures of reportingPreclinical Alzheimer's diseasePhenotypic effectsMemory advantageNeural underpinningsItem identityMemory impairmentMemory performanceMeasure memoryShort-term memoryAlzheimer's diseaseDissociative effectsE4 alleleEffect of genotypeE4 carriersAllelesMemoryObject locationGenotypesApolipoproteinShort-