2024
Association of Door-to-Balloon Time and one-Year Outcomes in hospital survivors of ST-elevation myocardial infarction
Sawano M, Kohsaka S, Murugiah K, Ishii H, Yamaji K, Takahashi J, Ozaki K, Amano T, Kozuma K. Association of Door-to-Balloon Time and one-Year Outcomes in hospital survivors of ST-elevation myocardial infarction. Journal Of Cardiology 2024 PMID: 38964710, DOI: 10.1016/j.jjcc.2024.06.009.Peer-Reviewed Original ResearchDoor-to-balloon timeST-elevation myocardial infarctionAdjusted hazard ratiosSurvivors of ST-elevation myocardial infarctionMyocardial infarctionPatients aged <Specific patient subgroupsAdverse cardiovascular eventsOne-year outcomesAcute coronary eventsRevascularization historyMACE riskCardiogenic shockCoronary revascularizationOutcomes RegistryCardiovascular eventsHospital survivorsPatient subgroupsCardiac arrestSubgroup analysisCardiovascular outcomesHazard ratioHigher comorbiditiesCoronary eventsPrimary preventionHeterogeneity in the Prognosis of Acute Kidney Injury Following Percutaneous Coronary Intervention
Hu J, Murugiah K, Xin X, Sawano M, Lu Y, Wilson F, Masoudi F, Messenger J, Krumholz H, Huang C. Heterogeneity in the Prognosis of Acute Kidney Injury Following Percutaneous Coronary Intervention. Journal Of The American Heart Association 2024, 13: e033649. PMID: 38390832, PMCID: PMC10944032, DOI: 10.1161/jaha.123.033649.Peer-Reviewed Original Research
2023
Wireless pulmonary artery sensor implantation in a unilateral lung transplant recipient
Kelly R, Bae J, Mansour A, Nagpal S, Hahn S, Murugiah K. Wireless pulmonary artery sensor implantation in a unilateral lung transplant recipient. Journal Of Cardiology Cases 2023, 28: 216-220. PMID: 38024115, PMCID: PMC10658300, DOI: 10.1016/j.jccase.2023.08.004.Peer-Reviewed Case Reports and Technical NotesPulmonary artery pressure monitorLung transplant recipientsLung transplantationCardioMEMS deviceTransplant recipientsHeart failurePressure monitorPulmonary artery injuryPulmonary artery pressureDevice-related complicationsSelective pulmonary angiographyFirst such caseArtery pressureVentricular failureArtery injuryHemodynamic managementPost transplantationHemodynamic assessmentPulmonary angiographyRight PAInvasive monitoringTransplantationSignificant tortuositySmall caliberTwo yearsPatterns of Digoxin Prescribing for Medicare Beneficiaries in the United States 2013-2019
See C, Wheelock K, Caraballo C, Khera R, Annapureddy A, Mahajan S, Lu Y, Krumholz H, Murugiah K. Patterns of Digoxin Prescribing for Medicare Beneficiaries in the United States 2013-2019. American Journal Of Medicine Open 2023, 10: 100048. PMID: 38213879, PMCID: PMC10783702, DOI: 10.1016/j.ajmo.2023.100048.Peer-Reviewed Original ResearchDigoxin prescriptionDigoxin useNew heart failure therapiesGeneral medicine physiciansHeart failure therapyMedicare Part D dataPart D dataDigoxin prescribingFailure therapyPrescriber characteristicsMedicine physiciansMedicare beneficiariesPrescribersLikely maleLogistic regressionDigoxinNew prescribersPrescriptionRecent dataCardiologySex Difference in Outcomes of Acute Myocardial Infarction in Young Patients
Sawano M, Lu Y, Caraballo C, Mahajan S, Dreyer R, Lichtman J, D'Onofrio G, Spatz E, Khera R, Onuma O, Murugiah K, Spertus J, Krumholz H. Sex Difference in Outcomes of Acute Myocardial Infarction in Young Patients. Journal Of The American College Of Cardiology 2023, 81: 1797-1806. PMID: 37137590, DOI: 10.1016/j.jacc.2023.03.383.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionNoncardiac hospitalizationsSubdistribution HRYounger patientsMyocardial infarctionSex differencesYoung womenCause-specific hospitalizationsCause of hospitalizationWorse health statusSignificant sex disparityNoncardiovascular hospitalizationsVIRGO StudyIndex episodeAdverse outcomesIncidence rateHospitalizationHigh riskSex disparitiesHealth statusPatientsU.S. hospitalsWomenInfarctionOutcomesInvasive Pulmonary Angiogram Performance and Interpretation in the Diagnosis of Pulmonary Thromboembolic Disease
Bae J, Murugiah K. Invasive Pulmonary Angiogram Performance and Interpretation in the Diagnosis of Pulmonary Thromboembolic Disease. Interventional Cardiology Clinics 2023, 12: 299-307. PMID: 37290835, PMCID: PMC10693920, DOI: 10.1016/j.iccl.2023.03.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsInvasive pulmonary angiographyPulmonary thromboembolic diseasePulmonary angiographyThromboembolic diseaseGold standard diagnostic testSelective pulmonary angiographyOptimal patient positioningStandard diagnostic testNoninvasive imaging modalityPulmonary vascular anatomyAngiographic patternsCatheter selectionVascular accessVascular anatomyArterial conditionsAngiographyDiagnostic testsPatient positioningImaging modalitiesDiseaseIntravascular Imaging Use by Intermediate to High-Volume US Operators – A Medicare Data Analysis
See C, Sawano M, Nagpal S, Chamie D, Curtis J, Murugiah K. Intravascular Imaging Use by Intermediate to High-Volume US Operators – A Medicare Data Analysis. Journal Of The Society For Cardiovascular Angiography & Interventions 2023, 2: 100977. PMID: 37854494, PMCID: PMC10584013, DOI: 10.1016/j.jscai.2023.100977.Peer-Reviewed Original ResearchEffect of the New Glomerular Filtration Rate Estimation Equation on Risk Predicting Models for Acute Kidney Injury After Percutaneous Coronary Intervention
Huang C, Murugiah K, Li X, Masoudi F, Messenger J, Williams K, Mortazavi B, Krumholz H. Effect of the New Glomerular Filtration Rate Estimation Equation on Risk Predicting Models for Acute Kidney Injury After Percutaneous Coronary Intervention. Circulation Cardiovascular Interventions 2023, 16: e012831. PMID: 37009734, PMCID: PMC10622038, DOI: 10.1161/circinterventions.122.012831.Peer-Reviewed Original ResearchTiming of Blood Draws Among Patients Hospitalized in a Large Academic Medical Center
Caraballo C, Mahajan S, Murugiah K, Mortazavi B, Lu Y, Khera R, Krumholz H. Timing of Blood Draws Among Patients Hospitalized in a Large Academic Medical Center. JAMA 2023, 329: 255-257. PMID: 36648476, PMCID: PMC9856620, DOI: 10.1001/jama.2022.21509.Peer-Reviewed Original Research
2022
Cardiac Status Among Heart Failure Patients With Implantable Cardioverter Defibrillators Before, During, and After COVID-19 Lockdown
Lu Y, Jones PW, Murugiah K, Caraballo C, Mahajan S, Massey D, Ahmed R, Bader E, Krumholz H. Cardiac Status Among Heart Failure Patients With Implantable Cardioverter Defibrillators Before, During, and After COVID-19 Lockdown. Journal Of Cardiac Failure 2022, 28: 1372-1374. PMID: 35690314, PMCID: PMC9187866, DOI: 10.1016/j.cardfail.2022.05.012.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillatorHeart failure patientsCRT-D devicesCardiac statusFailure patientsHeart failureCardioverter defibrillatorCardiac resynchronization therapy defibrillatorAcute cardiac conditionsMedical care deliveryInpatient careCardiac conditionsPhysiologic markersInpatient servicesPatientsCardiac healthCare deliveryMarked restrictionImplanted ICDsMinneapolis/Saint PaulSex subgroupsDefibrillatorCOVID-19Telemedicine servicesCOVID-19 lockdownSex-Specific Risk Factors Associated With First Acute Myocardial Infarction in Young Adults
Lu Y, Li SX, Liu Y, Rodriguez F, Watson KE, Dreyer RP, Khera R, Murugiah K, D’Onofrio G, Spatz ES, Nasir K, Masoudi FA, Krumholz HM. Sex-Specific Risk Factors Associated With First Acute Myocardial Infarction in Young Adults. JAMA Network Open 2022, 5: e229953. PMID: 35503221, PMCID: PMC9066284, DOI: 10.1001/jamanetworkopen.2022.9953.Peer-Reviewed Original ResearchConceptsFirst acute myocardial infarctionAcute myocardial infarctionPsychosocial risk factorsRisk factor profilePopulation attributable fractionRisk factor associationsRisk factorsOdds ratioYoung womenAMI subtypesMyocardial infarctionPrevention of AMIType 1 acute myocardial infarctionFactor profileRisk of AMITraditional cardiovascular risk factorsSex-specific risk factorsFactor associationsYoung adultsRisk factor modificationCardiovascular risk factorsStrong associationNutrition Examination SurveyCase-control studyPopulation-based controlsEvaluation of Temporal Trends in Racial and Ethnic Disparities in Sleep Duration Among US Adults, 2004-2018
Caraballo C, Mahajan S, Valero-Elizondo J, Massey D, Lu Y, Roy B, Riley C, Annapureddy AR, Murugiah K, Elumn J, Nasir K, Nunez-Smith M, Forman HP, Jackson CL, Herrin J, Krumholz HM. Evaluation of Temporal Trends in Racial and Ethnic Disparities in Sleep Duration Among US Adults, 2004-2018. JAMA Network Open 2022, 5: e226385. PMID: 35389500, PMCID: PMC8990329, DOI: 10.1001/jamanetworkopen.2022.6385.Peer-Reviewed Original ResearchConceptsCross-sectional studyLong sleep durationSleep durationWhite individualsBlack individualsLatino individualsEthnic differencesSerial cross-sectional studyNational Health Interview Survey dataHealth Interview Survey dataSelf-reported sleep durationShort sleep durationInterview Survey dataMiddle-aged adultsSelf-reported raceEstimated prevalenceMAIN OUTCOMELong sleepSleep deficiencyHigher household incomeEthnic disparitiesAge groupsHealth disparitiesPrevalenceSleep disparitiesDepression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience)
Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Lu Y, Spatz ES, Gupta A, Khera R, Ng VG, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Depression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience). The American Journal Of Cardiology 2022, 173: 33-38. PMID: 35365290, PMCID: PMC9133198, DOI: 10.1016/j.amjcard.2022.03.005.Peer-Reviewed Original ResearchConceptsSpontaneous coronary artery dissectionPatient Health Questionnaire-9Coronary artery dissectionPSS-14 scoreArtery dissectionBaseline PHQ-9 scoreAcute myocardial infarction patientsCardiovascular risk factorsPHQ-9 scoresAcute myocardial infarctionMyocardial infarction patientsYears of agePerceived Stress Scale scoresStress Scale scoresLinear mixed-effects analysisSCAD casesVIRGO StudyQuestionnaire-9Infarction patientsMixed-effects analysisMyocardial infarctionSubgroup analysisRisk factorsRoutine screeningClinical acuityHealth status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experience
Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Khera R, Lu Y, Spatz ES, Ng VG, Gupta A, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Health status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experience. PLOS ONE 2022, 17: e0265624. PMID: 35320296, PMCID: PMC8942215, DOI: 10.1371/journal.pone.0265624.Peer-Reviewed Original ResearchConceptsSpontaneous coronary artery dissectionAcute myocardial infarctionAMI patientsCoronary artery dissectionYoung AMI patientsHealth status outcomesHealth status instrumentsSCAD patientsArtery dissectionMyocardial infarctionStatus outcomesPatientsOutcomesHousehold incomeCollege educationInfarctionPhysical Activity Among Patients With Intracardiac Remote Monitoring Devices Before, During, and After COVID-19–Related Restrictions
Lu Y, Jones PW, Murugiah K, Caraballo C, Massey DS, Mahajan S, Ahmed R, Bader EM, Krumholz HM. Physical Activity Among Patients With Intracardiac Remote Monitoring Devices Before, During, and After COVID-19–Related Restrictions. Journal Of The American College Of Cardiology 2022, 79: 309-310. PMID: 35057917, PMCID: PMC8763290, DOI: 10.1016/j.jacc.2021.11.010.Peer-Reviewed Original Research
2021
Clinician Trends in Prescribing Direct Oral Anticoagulants for US Medicare Beneficiaries
Wheelock KM, Ross JS, Murugiah K, Lin Z, Krumholz HM, Khera R. Clinician Trends in Prescribing Direct Oral Anticoagulants for US Medicare Beneficiaries. JAMA Network Open 2021, 4: e2137288. PMID: 34870678, PMCID: PMC8649845, DOI: 10.1001/jamanetworkopen.2021.37288.Peer-Reviewed Original ResearchConceptsDOAC useAnticoagulant prescriptionOral anticoagulantsUS cliniciansMedicare beneficiariesNational clinical practice guidelinesElevated bleeding riskOral anticoagulant prescriptionsRetrospective cohort studyDirect oral anticoagulantsClinical practice guidelinesUS Medicare beneficiariesInternal medicine physiciansNumber of cliniciansAnticoagulant prescribingDOAC prescriptionsUnique cliniciansBleeding riskCohort studyAnticoagulant strategiesPrescription claimsPractice guidelinesMAIN OUTCOMEMost indicationsMedicare populationScope of Practice of US Interventional Cardiologists from an Analysis of Medicare Billing Data
Murugiah K, Chen L, Castro-Dominguez Y, Khera R, Krumholz HM. Scope of Practice of US Interventional Cardiologists from an Analysis of Medicare Billing Data. The American Journal Of Cardiology 2021, 160: 40-45. PMID: 34610872, DOI: 10.1016/j.amjcard.2021.08.041.Peer-Reviewed Original ResearchQuality of Cardiovascular Registries: Turning the Mirror Around
Murugiah K, Masoudi FA. Quality of Cardiovascular Registries: Turning the Mirror Around. Circulation Cardiovascular Quality And Outcomes 2021, 14: e008464. PMID: 34517725, DOI: 10.1161/circoutcomes.121.008464.Commentaries, Editorials and LettersHaemophilus Parainfluenzae mural endocarditis with large atrial septal defect and peripheral embolization
Bae JY, Murugiah K, McLeod GX, Anwer M, Howes CJ. Haemophilus Parainfluenzae mural endocarditis with large atrial septal defect and peripheral embolization. Journal Of Cardiology Cases 2021, 25: 149-152. PMID: 35261698, PMCID: PMC8888727, DOI: 10.1016/j.jccase.2021.08.002.Peer-Reviewed Case Reports and Technical NotesAtrial septal defectLarge atrial septal defectMural endocarditisInfective endocarditisSeptal defectLV massRisk factorsLeft ventriclePrior intravenous drug useBlood culture growthHemorrhagic cerebral eventsIntra-cardiac tumorPost-pericardiotomy syndromeRecent dental workIntravenous drug useUrgent surgical interventionValvular heart diseaseMitral valve repairVentricular septal defectCeftriaxone therapyPeripheral embolizationCerebral eventsDuke criteriaSymptom onsetSplenic infarctChanges in ST segment elevation myocardial infarction hospitalisations in China from 2011 to 2015
Zhou T, Li X, Lu Y, Murugiah K, Bai X, Hu S, Gao Y, Masoudi FA, Krumholz HM, Li J, . Changes in ST segment elevation myocardial infarction hospitalisations in China from 2011 to 2015. Open Heart 2021, 8: e001666. PMID: 34599073, PMCID: PMC8488733, DOI: 10.1136/openhrt-2021-001666.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionPrehospital delayMyocardial infarctionSegment elevation myocardial infarctionProportion of patientsElevation myocardial infarctionAcute cardiovascular careAcute myocardial infarctionWeighted national estimateHealth service capacityRisk-adjusted ratesAcute reperfusionEligible patientsHospital deathReperfusion therapyMedical chartsPatient characteristicsHospital treatmentPatient outcomesRandom cohortCardiovascular diseaseCardiovascular carePatientsNational estimatesStandardised definitions