Featured Publications
Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?
Tsang J, Dobaño C, VanDamme P, Moncunill G, Marchant A, Othman R, Sadarangani M, Koff W, Kollmann T. Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome? Trends In Immunology 2020, 41: 457-465. PMID: 32340868, PMCID: PMC7142696, DOI: 10.1016/j.it.2020.04.001.Peer-Reviewed Original Research
2022
Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses
Hagan T, Gerritsen B, Tomalin LE, Fourati S, Mulè MP, Chawla DG, Rychkov D, Henrich E, Miller HER, Diray-Arce J, Dunn P, Lee A, Levy O, Gottardo R, Sarwal M, Tsang J, Suárez-Fariñas M, Sékaly R, Kleinstein S, Pulendran B. Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses. Nature Immunology 2022, 23: 1788-1798. PMID: 36316475, PMCID: PMC9869360, DOI: 10.1038/s41590-022-01328-6.Peer-Reviewed Original ResearchConceptsAntibody responseDay 1Vaccine-induced antibodiesYellow fever vaccineHuman immune responseMechanisms of immunityB cell activationTranscriptional atlasFever vaccineDifferent vaccinesSystems vaccinologyImmune responseMost vaccinesDay 7Cell activationInnate immunityVaccineVaccinationImmunityCommon predictorsMolecular signaturesResponsePlasmablastsInterferonAntibodiesConsidering innate immune responses in SARS-CoV-2 infection and COVID-19
Diamond M, Lambris J, Ting J, Tsang J. Considering innate immune responses in SARS-CoV-2 infection and COVID-19. Nature Reviews Immunology 2022, 22: 465-470. PMID: 35788185, PMCID: PMC9252555, DOI: 10.1038/s41577-022-00744-x.Peer-Reviewed Original Research
2020
Maternal determinants of infant immunity: Implications for effective immunization and maternal-child health
Pasetti M, Ackerman M, Hoen A, Alter G, Tsang J, Marchant A. Maternal determinants of infant immunity: Implications for effective immunization and maternal-child health. Vaccine 2020, 38: 4491-4494. PMID: 32111530, PMCID: PMC9946685, DOI: 10.1016/j.vaccine.2020.01.056.Peer-Reviewed Original Research
2016
Humoral Fingerprinting of Immune Responses: ‘Super-Resolution’, High-Dimensional Serology
Lau W, Tsang J. Humoral Fingerprinting of Immune Responses: ‘Super-Resolution’, High-Dimensional Serology. Trends In Immunology 2016, 37: 167-169. PMID: 26830541, PMCID: PMC4955921, DOI: 10.1016/j.it.2016.01.003.Peer-Reviewed Original Research