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INFORMATION FOR

    Irene Chernova, MD, PhD

    Assistant Professor of Medicine (Nephrology)
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    Assistant Professor of Medicine (Nephrology)

    Biography

    Irene Chernova, MD, PhD is an Assistant Professor in the Department of Medicine who's studying the role of B cells in lupus nephritis in the Craft laboratory. Dr. Chernova received her MD and PhD in Immunology at the University of Pennsylvania and then completed her Internal Medicine and Nephrology fellowship training at Yale New Haven Hospital. The Craft lab allowed her to combine her interest in clinical kidney disease and love of kidney physiology with her training in Immunobiology and tackle questions regarding immune cells survival in the inflamed kidney. Specifically, Dr. Chernova is interested in how the unique ionic environment of the kidney influences the survival and function of infiltrating lymphocytes as well as broader questions concerning ion-immune cell interactions which she hopes will form the foundation of her independent laboratory.

    Last Updated on July 12, 2023.

    Appointments

    Other Departments & Organizations

    Education & Training

    PhD
    University of Pennsylvania Perelman School of Medicine (2015)
    MD
    University of Pennsylvania Perelman School of Medicine (2015)

    Board Certifications

    • Nephrology

      Certification Organization
      AB of Internal Medicine
      Original Certification Date
      2020

    • Internal Medicine

      Certification Organization
      AB of Internal Medicine
      Original Certification Date
      2018

    Research

    Research at a Glance

    Yale Co-Authors

    Frequent collaborators of Irene Chernova's published research.

    Publications

    Featured Publications

    2026

    • APOL1-risk alleles modulate T-cell receptor signaling to promote allograft rejection
      Pell J, Tanvir E, Sun Z, Chernova I, Reghuvaran A, Nagata S, Guerra M, Choi J, Al Chaar S, Mizuno H, Dong K, Tian X, Ishibe R, Franchin B, Cravedi P, Kumar A, Barsotti G, Shi H, De Kumar B, Smithson S, Song W, He J, Chong A, Pober J, Somlo S, Gibson I, Popik W, Zhang Z, Craft J, Azzi J, Murakami N, Ishibe S, Heeger P, Menon M. APOL1-risk alleles modulate T-cell receptor signaling to promote allograft rejection. Journal Of Clinical Investigation 2026 PMID: 42262888, DOI: 10.1172/jci193173.
      Peer-Reviewed Original Research
    • Dehydration promotes intracellular lipid synthesis and accumulation
      Carty J, Selvasingh J, Zuchowski Y, Nam H, Pénalva C, Nanayakkara G, Jennings E, Voss K, Adame E, Tossberg J, Yap W, Melzer M, Viquez O, McCall A, Piotrowski E, Bessho R, Cao S, Leaptrot K, Schrimpe-Rutledge A, Codreanu S, Sherrod S, McLean J, Trapani J, Cottam M, Wan M, Shrivastava D, Delker D, Wilson M, Hasenour C, Lantier L, Chernova I, Young J, Haase V, Vazquez-Medina J, Kosma D, Kim P, Cartailler J, Zhang M, Zent R, Harris R, Watts J, Terker A, Bock F, Rathmell J, Rodan A, Arroyo J. Dehydration promotes intracellular lipid synthesis and accumulation. Nature Communications 2026 PMID: 42185304, DOI: 10.1038/s41467-026-73534-x.
      Peer-Reviewed Original Research

    2024

    2023

    2022

    2021

    See All Publications

    Academic Achievements & Community Involvement

    Honors

    • honor

      Iva Dostanic, MD, PhD, Physician-Scientist Trainee Award

      05/12/2023Yale School of Medicine AwardYale Department of Internal Medicine

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