2023
Assessing transcriptomic reidentification risks using discriminative sequence models
Sadhuka S, Fridman D, Berger B, Cho H. Assessing transcriptomic reidentification risks using discriminative sequence models. Genome Research 2023, 33: 1101-1112. PMID: 37541758, PMCID: PMC10538488, DOI: 10.1101/gr.277699.123.Peer-Reviewed Original ResearchConceptsExpression quantitative trait lociGene expression dataExpression dataQuantitative trait lociOmics data setsGene expression profilesTrait lociGenomic regionsGenetic variationGene expressionExpression profilesMolecular insightsLinkage disequilibriumFunctional impactGenotypesTranscriptomicsLociSame individualDisequilibriumSequenceExpressionPrevious studiesFull extentData sets
2014
High-Resolution Transcriptome Analysis with Long-Read RNA Sequencing
Cho H, Davis J, Li X, Smith K, Battle A, Montgomery S. High-Resolution Transcriptome Analysis with Long-Read RNA Sequencing. PLOS ONE 2014, 9: e108095. PMID: 25251678, PMCID: PMC4176000, DOI: 10.1371/journal.pone.0108095.Peer-Reviewed Original ResearchConceptsAllele-specific expressionTranscriptome analysisRNA sequencingAlternative splicing patternsCell line GM12878RNA-seq protocolsSequencing of cDNARNA-seq datasetsIndividual transcriptomesGenomic elementsAlternative splicingSplicing patternsAllelic expressionTranscript quantificationRead lengthMRNA transcriptsMapping biasSequencingExpressionTranscriptomeGM12878SplicingTechnical hurdlesCDNAGenes