2009
The Acinar Cell and Early Pancreatitis Responses
Gorelick FS, Thrower E. The Acinar Cell and Early Pancreatitis Responses. Clinical Gastroenterology And Hepatology 2009, 7: s10-s14. PMID: 19896090, PMCID: PMC3073378, DOI: 10.1016/j.cgh.2009.07.036.Peer-Reviewed Original ResearchConceptsAcinar cellsAcid loadForms of pancreatitisAcute acid loadSpecific calcium channelsInhibition of secretionPathologic responseAcute pancreatitisPancreatic acinar cellsPathological elevationAbnormal calciumPancreatitis eventsCalcium-dependent phosphataseAlcohol abuseCalcium channelsHarmful stimuliSmall intestineCalcium releasePancreatitisTrypsinogen activationPancreatitis responsesCalcium occursSpecific intracellular signalsActivationIntracellular signals
1996
Effect of ethanol on cholecystokinin-stimulated zymogen conversion in pancreatic acinar cells
Katz M, Carangelo R, Miller LJ, Gorelick F. Effect of ethanol on cholecystokinin-stimulated zymogen conversion in pancreatic acinar cells. American Journal Of Physiology 1996, 270: g171-g175. PMID: 8772515, DOI: 10.1152/ajpgi.1996.270.1.g171.Peer-Reviewed Original ResearchConceptsPancreatic acinar cellsEffects of ethanolAbility of ethanolAcinar cellsHigh dosesLow dose cholecystokininCholecystokinin receptor antagonistDose of ethanolReceptor antagonistCholecystokininSmall intestineCholecystokinin receptorsEthanol treatmentActive formCarbamylcholineZymogen conversionIntracellular conversionDosesPancreatic zymogensCellsAntagonistDoseIntestine