2017
Do Animal Models of Acute Pancreatitis Reproduce Human Disease?
Gorelick FS, Lerch MM. Do Animal Models of Acute Pancreatitis Reproduce Human Disease? Cellular And Molecular Gastroenterology And Hepatology 2017, 4: 251-262. PMID: 28752114, PMCID: PMC5518169, DOI: 10.1016/j.jcmgh.2017.05.007.Peer-Reviewed Original ResearchAcute pancreatitisBiological disease mechanismsNonmalignant gastrointestinal diseasesPathophysiological disease mechanismsDisease mechanismsPotential therapeutic targetPaucity of dataHospital admissionCommon causeExperimental pancreatitis modelGastrointestinal diseasesPancreatitis modelTherapeutic targetAnimal modelsNatural historySpecific causesDiseaseDisease modelsPancreatitisDisease developmentUnderlying cellMolecular mechanismsHuman diseasesCauseLimited information
2005
Epidemiology and Pathophysiology of Acute Pancreatitis
Nagar A, Gorelick F. Epidemiology and Pathophysiology of Acute Pancreatitis. Clinical Gastroenterology 2005, 3-15. DOI: 10.1385/1-59259-815-3:003.Peer-Reviewed Original ResearchAcute pancreatitisNatural historyPathogenesis of APMultiorgan system failureRemote organ systemsAcute inflammatory processDegree of inflammationAcute attacksClinical courseCommon etiologyPancreatic inflammationSevere pancreatitisInflammatory processMild discomfortAlcohol abusePancreatitisRegional tissuesVariable involvementOrgan systemsComplete recoveryProapoptotic mediatorsPancreasInflammationIntracellular eventsZymogen granules