2023
Sleep Deficits Inter-Link Lower Basal Forebrain–Posterior Cingulate Connectivity and Perceived Stress and Anxiety Bidirectionally in Young Men
Li G, Zhong D, Li B, Chen Y, Yang L, Li C. Sleep Deficits Inter-Link Lower Basal Forebrain–Posterior Cingulate Connectivity and Perceived Stress and Anxiety Bidirectionally in Young Men. The International Journal Of Neuropsychopharmacology 2023, 26: 879-889. PMID: 37924270, PMCID: PMC10726414, DOI: 10.1093/ijnp/pyad062.Peer-Reviewed Original Research
2022
Identifying alcohol misuse biotypes from neural connectivity markers and concurrent genetic associations
Zhu T, Becquey C, Chen Y, Lejuez CW, Li CR, Bi J. Identifying alcohol misuse biotypes from neural connectivity markers and concurrent genetic associations. Translational Psychiatry 2022, 12: 253. PMID: 35710901, PMCID: PMC9203552, DOI: 10.1038/s41398-022-01983-1.Peer-Reviewed Original Research
2021
Alcohol use severity and the neural correlates of the effects of sleep disturbance on sustained visual attention
Li G, Chen Y, Tang X, Li CR. Alcohol use severity and the neural correlates of the effects of sleep disturbance on sustained visual attention. Journal Of Psychiatric Research 2021, 142: 302-311. PMID: 34416549, PMCID: PMC8429210, DOI: 10.1016/j.jpsychires.2021.08.018.Peer-Reviewed Original ResearchMeSH KeywordsBrainConnectomeFemaleHumansMagnetic Resonance ImagingSleepSleep Wake DisordersYoung AdultConceptsPittsburgh Sleep Quality IndexNeural correlatesAlcohol useSleep disturbancesReaction timeSustained visual attentionAlcohol misuseWhole-brain regressionGreater sleep disturbanceHuman Connectome ProjectSevere alcohol useVisual attentionSustained attentionNeural processesCognitive performanceLow accuracy rateLonger reaction timesPerformance accuracyConnectome ProjectPerceived friendship and binge drinking in young adults: A study of the Human Connectome Project data
Li G, Chen Y, Le TM, Zhornitsky S, Wang W, Dhingra I, Zhang S, Tang X, Li CR. Perceived friendship and binge drinking in young adults: A study of the Human Connectome Project data. Drug And Alcohol Dependence 2021, 224: 108731. PMID: 33915512, PMCID: PMC8641247, DOI: 10.1016/j.drugalcdep.2021.108731.Peer-Reviewed Original ResearchConceptsNon-binge drinkersRight posterior insulaPeer influenceYoung adult binge drinkingSocial cognition tasksSocial cognitive processingAlcohol useBinge drinkingWhole-brain regressionAdult binge drinkingYoung adultsMedial orbitofrontal cortexHuman Connectome ProjectRPI activityAlcohol use severityHuman Connectome Project dataSocial cognitionCognition tasksCognitive processingNeural correlatesNeural processesPotential sex differencesOrbitofrontal cortexPosterior insulaConnectome Project
2020
The Neural Processes Interlinking Social Isolation, Social Support, and Problem Alcohol Use
Le TM, Wang W, Zhornitsky S, Dhingra I, Chen Y, Zhang S, Li CR. The Neural Processes Interlinking Social Isolation, Social Support, and Problem Alcohol Use. The International Journal Of Neuropsychopharmacology 2020, 24: 333-343. PMID: 33211853, PMCID: PMC8059487, DOI: 10.1093/ijnp/pyaa086.Peer-Reviewed Original ResearchConceptsSocial supportVentral striatumVS connectivityAlcohol misuseSocial isolationWhole-brain multiple regressionProblem drinkingProblem drinkersAlcohol useResting-state functional magnetic resonanceFunctional magnetic resonanceMiddle frontal gyrusPotential protective factorsProblem alcohol usePrefrontal cortical modulationCognitive controlIndividual differencesNeural processesNeural substratesFrontal gyrusPrefrontal connectivityElevated stress responseFunctional connectivityPath analysisNeural connectivityA whole‐brain modeling approach to identify individual and group variations in functional connectivity
Zhao Y, Caffo BS, Wang B, Li C, Luo X. A whole‐brain modeling approach to identify individual and group variations in functional connectivity. Brain And Behavior 2020, 11: e01942. PMID: 33210469, PMCID: PMC7821576, DOI: 10.1002/brb3.1942.Peer-Reviewed Original ResearchConceptsWhole-brain functional connectivityFunctional connectivityResting-state functional connectivityVoxel-wise levelMedium-sized cohortBrain areasWhole brainGroup differencesResting-state fMRI datasetsHuman Connectome ProjectMatrix regression methodBrain subnetworksCovariatesConnectome ProjectSubjectsDimension reduction approachStatistical powerCohortModeling approachBrainStatistical methodsNeural responses to negative facial emotions: Sex differences in the correlates of individual anger and fear traits
Li G, Zhang S, Le TM, Tang X, Li CR. Neural responses to negative facial emotions: Sex differences in the correlates of individual anger and fear traits. NeuroImage 2020, 221: 117171. PMID: 32682098, PMCID: PMC7789231, DOI: 10.1016/j.neuroimage.2020.117171.Peer-Reviewed Original ResearchConceptsNegative facial emotionsFacial emotionsMiddle frontal cortexShape targetRetrosplenial cortexEmotion processingIndividual differencesProlonged RTHigher activationRight middle frontal cortexLeft retrosplenial cortexBilateral middle frontal cortexFrontal cortexSex-specific behavioralShape identificationHuman Connectome ProjectRegional brain responsesEmotion measuresAffective traitsNeural processesBrain responsesFear traitsNeural responsesEmotional disordersIndividuals' anger
2019
Neural correlates of enhanced response inhibition in the aftermath of stress
Chang J, Hu J, Li CR, Yu R. Neural correlates of enhanced response inhibition in the aftermath of stress. NeuroImage 2019, 204: 116212. PMID: 31546050, PMCID: PMC7509808, DOI: 10.1016/j.neuroimage.2019.116212.Peer-Reviewed Original ResearchConceptsInhibitory controlAcute stressMagnetic resonance imaging studySignal taskResonance imaging studyFunctional magnetic resonance imaging studyMiddle frontal gyrusTrier Social Stress TestControl conditionSignal reaction timeAftermath of stressSocial Stress TestImaging studiesCognitive functionDynamic causal modelingStress exposureEnhanced response inhibitionPilot studyFrontal gyrusLife stressNeural mechanismsStriatumResponse inhibitionNeural correlatesImmediate effectsAn information network flow approach for measuring functional connectivity and predicting behavior
Kumar S, Yoo K, Rosenberg MD, Scheinost D, Constable RT, Zhang S, Li C, Chun MM. An information network flow approach for measuring functional connectivity and predicting behavior. Brain And Behavior 2019, 9: e01346. PMID: 31286688, PMCID: PMC6710195, DOI: 10.1002/brb3.1346.Peer-Reviewed Original ResearchConceptsFunctional brain connectivityFunctional magnetic resonance imagingFMRI time coursesIndividual differencesTask performanceMeasures of attentionSustained attention taskAttention task performanceResting-state fMRI dataSample of individualsAttention taskFMRI dataFunctional connectivityFC patternsBrain connectivityPearson correlationInformation theory statisticsInformation flowMachine-learning modelsMeasuresMagnetic resonance imagingAttentionNetwork flow approachTime courseDifferent datasets
2017
Connectome-based predictive modeling of attention: Comparing different functional connectivity features and prediction methods across datasets
Yoo K, Rosenberg MD, Hsu WT, Zhang S, Li CR, Scheinost D, Constable RT, Chun MM. Connectome-based predictive modeling of attention: Comparing different functional connectivity features and prediction methods across datasets. NeuroImage 2017, 167: 11-22. PMID: 29122720, PMCID: PMC5845789, DOI: 10.1016/j.neuroimage.2017.11.010.Peer-Reviewed Original Research
2016
Methylphenidate Modulates Functional Network Connectivity to Enhance Attention
Rosenberg MD, Zhang S, Hsu WT, Scheinost D, Finn ES, Shen X, Constable RT, Li CS, Chun MM. Methylphenidate Modulates Functional Network Connectivity to Enhance Attention. Journal Of Neuroscience 2016, 36: 9547-9557. PMID: 27629707, PMCID: PMC5039242, DOI: 10.1523/jneurosci.1746-16.2016.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderSustained attentionWhole-brain connectivity patternsFunctional brain networksHyperactivity disorderBrain networksConnectivity patternsConnectome-based predictive modeling approachWhole-brain functional connectivity patternsWhole-brain functional connectivity networksSustained attention taskStop-signal taskDose of methylphenidateFunctional network connectivityCausal roleFunctional connectivity patternsHealthy adultsAttention taskCognitive abilitiesPromising neuromarkerNetwork strengthBehavioral predictionsADHD treatmentConnectivity signaturesFunctional connectivity networks
2015
Resting-State Functional Connectivity of the Locus Coeruleus in Humans: In Comparison with the Ventral Tegmental Area/Substantia Nigra Pars Compacta and the Effects of Age
Zhang S, Hu S, Chao HH, Li CR. Resting-State Functional Connectivity of the Locus Coeruleus in Humans: In Comparison with the Ventral Tegmental Area/Substantia Nigra Pars Compacta and the Effects of Age. Cerebral Cortex 2015, 26: 3413-3427. PMID: 26223261, PMCID: PMC4961017, DOI: 10.1093/cercor/bhv172.Peer-Reviewed Original ResearchConceptsVentral tegmental area/substantia nigra pars compactaSubstantia nigra pars compactaLocus coeruleusPars compactaFunctional connectivityResting-state functional connectivityCerebral functional connectivityNumerous animal studiesFronto-parietal cortexRight anterior insulaResting-state fMRI dataEffect of ageCerebral cortexNoradrenergic inputCognitive motor controlAnimal studiesCortex decreasesHealthy adultsCerebellum increasesMidbrain nucleiBilateral amygdalaMidbrain structuresAnterior insulaCognitive manifestationsMotor control
2014
Error-related functional connectivity of the thalamus in cocaine dependence
Zhang S, Hu S, Bednarski SR, Erdman E, Li CS. Error-related functional connectivity of the thalamus in cocaine dependence. NeuroImage Clinical 2014, 4: 585-592. PMID: 24936409, PMCID: PMC4053644, DOI: 10.1016/j.nicl.2014.01.015.Peer-Reviewed Original ResearchConceptsVentral medial prefrontal cortexFunctional connectivityCognitive controlGeneralized psychophysiological interaction analysisTask-related processesPsychophysiological interaction analysisSubgenual anterior cingulate cortexCocaine dependenceMedial prefrontal cortexAnterior cingulate cortexError processingExecutive functionCocaine-dependent patientsPrefrontal cortexCingulate cortexRelated activationSubstance misuseCocaine useDrug useThalamic connectivity