2020
Age-Related Structural and Functional Changes of the Hippocampus and the Relationship with Inhibitory Control
Hu S, Li CR. Age-Related Structural and Functional Changes of the Hippocampus and the Relationship with Inhibitory Control. Brain Sciences 2020, 10: 1013. PMID: 33352718, PMCID: PMC7766783, DOI: 10.3390/brainsci10121013.Peer-Reviewed Original ResearchStop-signal reaction timeGray matter volumeHippocampal gray matter volumePosterior hippocampusSequential effectsAge-related changesAnterior hippocampal activationTrial reaction timeStop-signal taskDistinct neural markersRight posterior hippocampusSignal reaction timeStop-signal probabilityRegional activityReaction timeAge-Related StructuralCognitive controlCognitive agingHippocampal activationProactive controlSignal taskBehavioral performanceAge-related reductionInhibitory controlHippocampal activity
2019
Imaging the effects of age on proactive control in healthy adults
Hu S, Job M, Jenks SK, Chao HH, Li CR. Imaging the effects of age on proactive control in healthy adults. Brain Imaging And Behavior 2019, 13: 1526-1537. PMID: 31011949, PMCID: PMC6812594, DOI: 10.1007/s11682-019-00103-w.Peer-Reviewed Original ResearchConceptsInferior occipital gyrusStop-signal reaction timePrefrontal cortexProactive controlProactive inhibitionOlder adultsReactive inhibitionSuperior parietal lobuleSequential effectsEffect of ageSignal reaction timeCaudate headDistinct neural processesParacentral lobuleTrial reaction timeVentromedial prefrontal cortexLateral prefrontal cortexHealthy adultsNeural changesNeural plasticityOccipital gyrusParietal lobuleReaction timeYoung adultsBelief Model
2018
Motor Preparation Disrupts Proactive Control in the Stop Signal Task
Wang W, Hu S, Ide JS, Zhornitsky S, Zhang S, Yu AJ, Li CR. Motor Preparation Disrupts Proactive Control in the Stop Signal Task. Frontiers In Human Neuroscience 2018, 12: 151. PMID: 29780308, PMCID: PMC5945807, DOI: 10.3389/fnhum.2018.00151.Peer-Reviewed Original ResearchStop-signal taskGranger causal connectivityMotor preparationSignal taskMotor preparatory activityFP activationCausal connectivityMotor responseTrial reaction timeDirect neural evidenceConflict anticipationBrain activationTrialsSequential effectsSuccess rateRegional activationResponse slowingActivationPreparatory activityCertain individualsDifferent patternsHigh levelsControlSlowingNeural evidence
2015
Conflict anticipation in alcohol dependence — A model-based fMRI study of stop signal task
Hu S, Ide JS, Zhang S, Sinha R, Li CS. Conflict anticipation in alcohol dependence — A model-based fMRI study of stop signal task. NeuroImage Clinical 2015, 8: 39-50. PMID: 26106526, PMCID: PMC4473266, DOI: 10.1016/j.nicl.2015.03.008.Peer-Reviewed Original ResearchConceptsStop-signal reaction timeHealthy control individualsConflict anticipationAlcohol dependenceCognitive controlProactive controlSignal taskSequential effectsModel-based fMRI studyAlcohol consumptionStop signalPre-supplementary motor areaBilateral inferior parietal cortexPerigenual anterior cingulate cortexSignificant sequential effectInferior parietal cortexSignal reaction timeWhole-brain responsesAnterior cingulate cortexRecent alcohol consumptionNeural correlatesFMRI studyNeural markersMotor areaTrial onset