2017
Altered Functional Connectivity of the Basal Nucleus of Meynert in Mild Cognitive Impairment: A Resting-State fMRI Study
Li H, Jia X, Qi Z, Fan X, Ma T, Ni H, Li CR, Li K. Altered Functional Connectivity of the Basal Nucleus of Meynert in Mild Cognitive Impairment: A Resting-State fMRI Study. Frontiers In Aging Neuroscience 2017, 9: 127. PMID: 28522971, PMCID: PMC5415557, DOI: 10.3389/fnagi.2017.00127.Peer-Reviewed Original ResearchMild cognitive impairmentHealthy controlsAuditory Verbal Learning TestCognitive impairmentAlzheimer's diseaseBasal nucleusMCI patientsLow frequency fMRI signal fluctuationsFunctional connectivityResting-state functional magnetic resonance imagingResting-State fMRI StudyCortical cholinergic innervationCholinergic basal forebrainAltered functional connectivityFunctional magnetic resonance imagingMagnetic resonance imagingFMRI signal fluctuationsCholinergic dysfunctionCholinergic innervationVerbal Learning TestBasal forebrainClinical assessmentCognitive dysfunctionCholinergic basisLeft insula
2016
Resting-State Functional Connectivity of the Basal Nucleus of Meynert in Cigarette Smokers: Dependence Level and Gender Differences
Zhang S, Hu S, Fucito LM, Luo X, Mazure CM, Zaborszky L, Li CR. Resting-State Functional Connectivity of the Basal Nucleus of Meynert in Cigarette Smokers: Dependence Level and Gender Differences. Nicotine & Tobacco Research 2016, 19: 452-459. PMID: 27613921, PMCID: PMC6074817, DOI: 10.1093/ntr/ntw209.Peer-Reviewed Original ResearchConceptsSupplementary motor areaCigarette smokersCholinergic systemCigarette smokingFemale smokersMotor areaBasal nucleusFunctional connectivityResting-state functional connectivityGender-matched nonsmokersWhole-brain functional connectivityNicotine dependence scoresBilateral anterior insulaNicotinic acetylcholine receptorsPosterior cingulate cortexCurrent smokersMale smokersCerebral cortexCholinergic projectionsMultiple imaging modalitiesBasal forebrainGreater negative connectivitySex-specific differencesSmokersFagerström Test