Astha Chichra, MBBS, MD
Associate Professor TermCards
About
Research
Publications
2026
C72-05 Assessment of Diaphragmatic Dysfunction With Point-Of-Care Ultrasound in Patients With Prolonged Mechanical Ventilation in Medical Intensive Care Unit
Um H, Honiden S, Chichra A. C72-05 Assessment of Diaphragmatic Dysfunction With Point-Of-Care Ultrasound in Patients With Prolonged Mechanical Ventilation in Medical Intensive Care Unit. American Journal Of Respiratory And Critical Care Medicine 2026, 212: aamag162.4733. DOI: 10.1093/ajrccm/aamag162.4733.Peer-Reviewed Original ResearchProlonged mechanical ventilationMedical intensive care unitPoint of care ultrasoundDiaphragmatic excursionMechanical ventilationIntensive care unitDiaphragmatic ultrasoundDiaphragmatic dysfunctionRespiratory failureNoninvasive markerVentilator-dependentAssociated with successful weaningAcute hypoxemic respiratory failureCare unitTertiary medical intensive care unitHypercarbic respiratory failureMinimal ventilator supportHypoxemic respiratory failureSpontaneous breathing trialM-mode ultrasoundPoint-of-care ultrasoundSerial ultrasoundsBreathing trialSuccessful weaningPatient-centered outcomes
2025
Improved Ventilator Weaning and Decannulation Outcomes with Enhanced Staffing Model
Carney H, Chichra A, Schneider N, Fogerty R, Kazmi T. Improved Ventilator Weaning and Decannulation Outcomes with Enhanced Staffing Model. Hospital Topics 2025, ahead-of-print: 1-7. PMID: 39945331, DOI: 10.1080/00185868.2025.2464129.Peer-Reviewed Original ResearchAdvanced practice providersStaffing modelsProvider continuityMechanical ventilation weaningInpatient settingContinuity of careVentilator weaningDecannulation rateStepdown unitGroup of physiciansPractice providersMethods: DataInpatient stayStaffingDecannulation protocolProvidersTracheostomy decannulationDecannulation outcomeDecannulationPatientsVentilationCarePhysiciansPositive effectSets
2023
Managing the Chronically Ventilated Critically Ill Population
Chichra A, Tickoo M, Honiden S. Managing the Chronically Ventilated Critically Ill Population. Journal Of Intensive Care Medicine 2023, 39: 703-714. PMID: 37787184, DOI: 10.1177/08850666231203601.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCritical illnessMechanical ventilationAcute critical illnessCritically Ill PopulationIntensive care therapyPopulation of patientsCare therapyAcute periodHigh morbidityIntensive carePalliative careDisease burdenIll populationNeuroendocrine disordersPsychiatric effectsHealthcare costsPsychiatric issuesNutritional deficienciesChances of survivalPatientsWeaning strategiesSignificant increaseIllnessCareVentilationA Tool to Assess Competence in Critical Care Ultrasound Based on Entrustable Professional Activities
Israel H, Slade M, Gielissen K, Liu R, Pisani M, Chichra A. A Tool to Assess Competence in Critical Care Ultrasound Based on Entrustable Professional Activities. ATS Scholar 2023, 4: 61-75. PMID: 37089679, PMCID: PMC10117444, DOI: 10.34197/ats-scholar.2022-0063oc.Peer-Reviewed Original ResearchCritical care ultrasoundCritical care fellowsCare ultrasoundStudy periodAssessment toolEntrustable professional activitiesCritical Care SocietyResponse process validityAssessment of validitySingle institutionExpert consensusNominal group techniqueEntrustment scoresSufficient validity evidenceRegression analysisScoresContent validityClinical workflowProcess validityRegression modelsValidity evidenceUltrasoundHigh agreementCore Entrustable Professional ActivitiesICUA Tool to Assess Competence in Critical Care Ultrasound Based on Entrustable Professional Activities.
Israel HP, Slade M, Gielissen K, Liu RB, Pisani MA, Chichra A. A Tool to Assess Competence in Critical Care Ultrasound Based on Entrustable Professional Activities. ATS Scholar. 2023 Jan:ats-scholar.Peer-Reviewed Original Research
2022
A commentary on: Extended Lung Ultrasound to Differentiate Between Pneumonia and Atelectasis in Critically Ill Patients: A Diagnostic Accuracy Study.
Chichra A. A commentary on: Extended Lung Ultrasound to Differentiate Between Pneumonia and Atelectasis in Critically Ill Patients: A Diagnostic Accuracy Study. PracticeUpdate website. Available at: https://www.practiceupdate.com/content/extended-lung-ultrasound-to-differentiate-between-pneumonia-and-atelectasis-in-critically-ill-patients/136106/65/20/1. Accessed June 09, 2022Commentaries, Editorials and LettersCombined Use of ECMO, Prone Positioning, and APRV in the Management of Severe COVID-19 Patients
Ong S, Tantawy H, Assi R, Chichra A, Treggiari M. Combined Use of ECMO, Prone Positioning, and APRV in the Management of Severe COVID-19 Patients. Therapeutic Advances In Pulmonary And Critical Care Medicine 2022, 16: 11795484221134451. PMID: 36419562, PMCID: PMC9677293, DOI: 10.1177/11795484221134451.Peer-Reviewed Original ResearchAcute respiratory distress syndromeExtracorporeal membrane oxygenationCOVID-19-associated acute respiratory distress syndromeProne positioningVV-ECMODeep tissue injuryTissue injurySevere COVID-19-associated acute respiratory distress syndromeVeno-venous (VV) ECMOCOVID-19 acute respiratory distress syndromeSevere COVID-19 patientsTreatment-related complicationsConsecutive adult patientsRespiratory distress syndromeCOVID-19 populationCOVID-19 patientsHospital mortalityVasopressor requirementECMO supportAdult patientsCohort studyHemodynamic profilePhysiologic improvementDistress syndromeMembrane oxygenation
2021
284: METHYLPREDNISOLONE VERSUS USUAL CARE FOR COVID-19-ASSOCIATED ACUTE RESPIRATORY DISTRESS SYNDROME
Owusu K, Ammar M, Ammar A, Chess A, Siner J, Fajardo E, Chichra A. 284: METHYLPREDNISOLONE VERSUS USUAL CARE FOR COVID-19-ASSOCIATED ACUTE RESPIRATORY DISTRESS SYNDROME. Critical Care Medicine 2021, 50: 127-127. DOI: 10.1097/01.ccm.0000807460.83646.b2.Peer-Reviewed Original Research1143: HYPOXIC RESPIRATORY FAILURE CAUSED BY OSIMERTINIB-INDUCED ACUTE FIBRINOUS AND ORGANIZING PNEUMONIA
Hunter N, Matsumoto N, Carpio A, Chichra A. 1143: HYPOXIC RESPIRATORY FAILURE CAUSED BY OSIMERTINIB-INDUCED ACUTE FIBRINOUS AND ORGANIZING PNEUMONIA. Critical Care Medicine 2021, 50: 570-570. DOI: 10.1097/01.ccm.0000810896.08898.49.Peer-Reviewed Original ResearchMalignant hyperthermia in severe COVID-19: 2 case reports
Ehteshami-Afshar S, Nikooie R, Reddy P, Chichra A, Siegel M. Malignant hyperthermia in severe COVID-19: 2 case reports. Emergency And Critical Care Medicine 2021, 1: 45-48. PMID: 38630110, PMCID: PMC8447731, DOI: 10.1097/ec9.0000000000000013.Peer-Reviewed Original Research