Arjun Ravishankar, MBBS
Clinical FellowAbout
Research
Publications
Featured Publications
Epigenetic memory of coronavirus infection in innate immune cells and their progenitors
Cheong J, Ravishankar A, Sharma S, Parkhurst C, Grassmann S, Wingert C, Laurent P, Ma S, Paddock L, Miranda I, Karakaslar E, Nehar-Belaid D, Thibodeau A, Bale M, Kartha V, Yee J, Mays M, Jiang C, Daman A, Martinez de Paz A, Ahimovic D, Ramos V, Lercher A, Nielsen E, Alvarez-Mulett S, Zheng L, Earl A, Yallowitz A, Robbins L, LaFond E, Weidman K, Racine-Brzostek S, Yang H, Price D, Leyre L, Rendeiro A, Ravichandran H, Kim J, Borczuk A, Rice C, Jones R, Schenck E, Kaner R, Chadburn A, Zhao Z, Pascual V, Elemento O, Schwartz R, Buenrostro J, Niec R, Barrat F, Lief L, Sun J, Ucar D, Josefowicz S. Epigenetic memory of coronavirus infection in innate immune cells and their progenitors. Cell 2023, 186: 3882-3902.e24. PMID: 37597510, PMCID: PMC10638861, DOI: 10.1016/j.cell.2023.07.019.Peer-Reviewed Original Research
2026
Breaking the Immune Sanctuary: Targeting Metastatic Niches.
Ravishankar A, Ramamoorthi G, Weiss T, Le Rhun E, Czerniecki B, Sundar R. Breaking the Immune Sanctuary: Targeting Metastatic Niches. American Society Of Clinical Oncology Educational Book 2026, 46: e517520. PMID: 42208002, DOI: 10.1200/edbk-26-517520.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPlatelet proteomics on less than a drop of previously frozen, non-citrate plasma
Tabang D, Korff K, Brannon K, Tilburg J, Mandal K, Viodé A, van Zalm P, Ravishankar A, Cheong J, Schott O, Arnaout R, Josefowicz S, Italiano J, Steen H, Smolen K. Platelet proteomics on less than a drop of previously frozen, non-citrate plasma. Molecular Omics 2026, 22: aaiag017. PMID: 42059667, DOI: 10.1093/molecular-omics/aaiag017.Peer-Reviewed Original ResearchHow We Evaluate and Treat Leukemic Presentations of Mature T-Cell Lymphomas
Ravishankar A, Somaya V, Qureshi H, Kiwan A, Montanari F, Girardi M, Foss F, Sethi T. How We Evaluate and Treat Leukemic Presentations of Mature T-Cell Lymphomas. Cancers 2026, 18: 965. PMID: 41899567, PMCID: PMC13024611, DOI: 10.3390/cancers18060965.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsThis study investigates diagnostic and treatment strategies for mature T-cell leukemias, emphasizing tailored approaches for subtypes like T-PLL, ATLL, T-LGL, and Sézary syndrome.
2024
Clinical outcomes and safety of immune checkpoint inhibitors in patients with solid tumors and paraneoplastic syndromes
Nassar A, El Zarif T, Khalid A, Rahme S, Zhong C, Kwak L, Salame M, Farhat E, Freeman D, El-Am E, Ravishankar A, Ahmad B, Nana F, Kaldas D, Naqash A, Sharon E, LeBoeuf N, Cortellini A, Malgeri A, Gupta S, Al-Hader A, Sparks J, Linnoila J, Hamnvik O, Mouhieddine T, Marron T, Parikh K, McKay R, Dilling T, Choueiri T, Adib E, Najem E, Kim S, Sonpavde G. Clinical outcomes and safety of immune checkpoint inhibitors in patients with solid tumors and paraneoplastic syndromes. Journal For ImmunoTherapy Of Cancer 2024, 12: e008724. PMID: 38448038, PMCID: PMC10916116, DOI: 10.1136/jitc-2023-008724.Peer-Reviewed Original Research
2023
Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19
Kusakabe T, Lin W, Cheong J, Singh G, Ravishankar A, Yeung S, Mesko M, DeCelie M, Carriche G, Zhao Z, Rand S, Doron I, Putzel G, Worgall S, Cushing M, Westblade L, Inghirami G, Parkhurst C, Guo C, Schotsaert M, García-Sastre A, Josefowicz S, Salvatore M, Iliev I. Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19. Nature Immunology 2023, 24: 1879-1889. PMID: 37872315, PMCID: PMC10805066, DOI: 10.1038/s41590-023-01637-4.Peer-Reviewed Original ResearchSex Differences in Clinical Presentation and Management in Eosinophilic Esophagitis
Fogla R, Glaubitz E, Bhatia S, Ravishankar A, Andy C, Niec R, Katz P. Sex Differences in Clinical Presentation and Management in Eosinophilic Esophagitis. Foregut The Journal Of The American Foregut Society 2023, 3: 141-148. DOI: 10.1177/26345161231170590.Peer-Reviewed Original Research
2022
Angiopoietin 2 Is Associated with Vascular Necroptosis Induction in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome
Price D, Benedetti E, Hoffman K, Gomez-Escobar L, Alvarez-Mulett S, Capili A, Sarwath H, Parkhurst C, Lafond E, Weidman K, Ravishankar A, Cheong J, Batra R, Büyüközkan M, Chetnik K, Easthausen I, Schenck E, Racanelli A, Outtz Reed H, Laurence J, Josefowicz S, Lief L, Choi M, Schmidt F, Borczuk A, Choi A, Krumsiek J, Rafii S. Angiopoietin 2 Is Associated with Vascular Necroptosis Induction in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome. American Journal Of Pathology 2022, 192: 1001-1015. PMID: 35469796, PMCID: PMC9027298, DOI: 10.1016/j.ajpath.2022.04.002.Peer-Reviewed Original ResearchPublisher Correction: Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability
Guo P, Liu Y, Geng F, Daman A, Liu X, Zhong L, Ravishankar A, Lis R, Barcia Durán J, Itkin T, Tang F, Zhang T, Xiang J, Shido K, Ding B, Wen D, Josefowicz S, Rafii S. Publisher Correction: Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability. Nature Cell Biology 2022, 24: 279-279. PMID: 35058593, DOI: 10.1038/s41556-022-00851-w.Commentaries, Editorials and Letters
2021
Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability
Guo P, Liu Y, Geng F, Daman A, Liu X, Zhong L, Ravishankar A, Lis R, Barcia Durán J, Itkin T, Tang F, Zhang T, Xiang J, Shido K, Ding B, Wen D, Josefowicz S, Rafii S. Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability. Nature Cell Biology 2021, 24: 99-111. PMID: 34961794, PMCID: PMC9166935, DOI: 10.1038/s41556-021-00795-7.Peer-Reviewed Original ResearchAnimalsCD8-Positive T-LymphocytesCell Cycle ProteinsCell LineChromatinGranulocytesHematopoiesisHematopoietic Stem CellsHistone ChaperonesHistonesHuman Umbilical Vein Endothelial CellsHumansMacrophagesMethylationMiceMice, Inbred C57BLMice, KnockoutMyelopoiesisPromoter Regions, GeneticProtein Processing, Post-TranslationalTranscription Factors