Prostate Ablation

Transcript

• 00:05So ablation is using energy
• 00:07of some form to destroy
• 00:09tissue. In this case, we're
• 00:11talking about prostate ablation, so
• 00:12we use different types of
• 00:14energy. Could be heat, cold.
• 00:16We actually use electricity as
• 00:18well to destroy prostate tissue,
• 00:20usually prostate cancer.
• 00:22Because we use imaging guidance,
• 00:25we're able to place the
• 00:26probes or target the tissue
• 00:28in a very precise manner
• 00:30and
• 00:31destroy only the tumor and
• 00:32the surrounding tissue,
• 00:34but we're able to spare
• 00:36other structures that we don't
• 00:38want to damage.
• 00:39This is in contrast to
• 00:41whole prostate therapies like prostatectomy
• 00:44or surgery where we are
• 00:45removing the entire prostate or
• 00:47radiation therapy which is traditionally
• 00:49done to the entire prostate
• 00:50with a margin of treatment
• 00:51even outside the prostate.
• 00:54So doing a subtotal treatment
• 00:56where we are able to
• 00:57target the
• 00:58prostate cancer primarily
• 01:00with a safety margin around
• 01:02that
• 01:03really allows for preservation of
• 01:05function or the least possible
• 01:07damage to a man's urinary
• 01:10function, sexual function, bowel function
• 01:12that we can achieve,
• 01:14with a prostate cancer treatment.
• 01:19The three different technologies that
• 01:21we have currently at Yale
• 01:23are Tulsa,
• 01:25which uses
• 01:26high intensity ultrasound waves. We're
• 01:28able to heat the prostate
• 01:30tissue from the inside out.
• 01:32Cryoablation
• 01:33is sort of the opposite.
• 01:34It uses cold energy
• 01:36to similarly destroy the cells.
• 01:38And then IRE or Irreversible
• 01:41Electroporation
• 01:42uses electricity, and it actually
• 01:44passes electricity between a couple
• 01:46small needles,
• 01:47and that
• 01:48results in cell lysis or
• 01:50the death of the cells.
• 01:52There are highlights to each
• 01:54of these. These. Right? Tulsa
• 01:56probably of any ablation technology
• 01:58out there currently has the
• 02:00best treatment planning, treatment monitoring
• 02:03in real time and ability.
• 02:04To target certain areas of
• 02:06the prostate avoiding damage to
• 02:08other areas,
• 02:09and effectively treat cancer.
• 02:12Cryoablation,
• 02:13we know, is very effective,
• 02:15and it can be used
• 02:16in certain anatomical locations more
• 02:18easily than others and can
• 02:20be done quickly.
• 02:21And then IRE
• 02:23for people that are very
• 02:24concerned about preserving their erectile
• 02:26function,
• 02:27it seems to have the
• 02:28least impact on that.
• 02:30So those are kind of
• 02:31the highlights that allow us
• 02:33to really provide the top
• 02:35level care.
• 02:37At Yale, we understand that
• 02:40prostate cancer treatment options
• 02:42should be individualized to a
• 02:43patient.
• 02:45It's always really important to
• 02:47take into consideration
• 02:49factors that contribute to a
• 02:50patient's prostate cancer risk. But
• 02:52it's also really important to
• 02:54take into account their
• 02:56personal preferences,
• 02:57their individual anatomy,
• 02:59and being able to offer
• 03:01this treatment,
• 03:03to patients who have intermediate
• 03:05risk prostate cancer and
• 03:08wish to avoid surgery or
• 03:10radiation, but also are uncomfortable
• 03:12with
• 03:13just being on active surveillance
• 03:15alone.
• 03:16This is an important treatment
• 03:17option that fills a gap.
• 03:19We know that ablation therapies
• 03:20are safe.
• 03:22They are not without risks,
• 03:24but they are safe, and
• 03:25on average have fewer side
• 03:27effects
• 03:28than we would see with
• 03:29surgery or see with radiation.
• 03:31We know from a couple
• 03:31of trials that we actually
• 03:33have been involved in here
• 03:35at Yale
• 03:36that this treatment is in
• 03:37fact effective
• 03:39at cancer control and also
• 03:41effective at avoiding or lowering
• 03:43risk of urinary and sexual
• 03:45side effects.
• 03:46I think it provides patients
• 03:47who
• 03:49are motivated
• 03:50to maintain their quality of
• 03:52life,
• 03:53an opportunity to pursue therapies
• 03:55that are not as damaging
• 03:57to their,
• 03:59way of life and often
• 04:00their psychological
• 04:02sense of self.