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INFORMATION FOR

    How Anesthesia Works - Yale Medicine Explains

    April 22, 2025

    Transcript

    • 00:05We have nerve endings
    • 00:07everywhere,
    • 00:08literally everywhere.
    • 00:10And ordinarily,
    • 00:12from these nerve endings,
    • 00:13pain gets transmitted.
    • 00:16You can kind of think
    • 00:17of them as
    • 00:18your early warning system. They
    • 00:20are the first line of
    • 00:21defense that you have against
    • 00:22threats in your environment.
    • 00:25So it could be a
    • 00:25cut. It could be an
    • 00:27incision. It could be, something
    • 00:29blunt. That initiates
    • 00:31a chemical response
    • 00:33that is transmitted to the
    • 00:34spinal cord then travel to
    • 00:36the brain and that's how
    • 00:37pain is essentially perceived.
    • 00:40Now this is in comparison
    • 00:41to chronic pain. Chronic pain
    • 00:43is essentially a
    • 00:44response. Right? So this is
    • 00:45an ongoing false alarm that
    • 00:48really does not provide you
    • 00:49or the body any benefit.
    • 00:51Pain medications and anesthetics
    • 00:54utilize
    • 00:55a very large number of
    • 00:56different mechanisms.
    • 00:57But in general, it's interrupting
    • 01:00those pathways.
    • 01:01From wherever
    • 01:02the insult or the incision
    • 01:04is or the puncture is
    • 01:05and disrupt that communication to
    • 01:07the spinal cord.
    • 01:08So that pain is ultimately
    • 01:10not experienced.
    • 01:15There are a few different
    • 01:16types of anesthesia that we
    • 01:18use now. One is a
    • 01:19local anesthetic, right, which many
    • 01:21of you have probably experienced
    • 01:22in your doctor's office or
    • 01:23your dentist office.
    • 01:25We have regional anesthetic techniques,
    • 01:27what we call monitored anesthesia
    • 01:29care which is a very
    • 01:30deep sedation
    • 01:31and then general anesthesia.
    • 01:35Regional anesthesia
    • 01:36is an anesthetic technique by
    • 01:38which we administer
    • 01:40local an aesthetic in and
    • 01:41around large nerves that provide
    • 01:44sensation to significant sections of
    • 01:46our extremities or torso.
    • 01:49Those are sometimes done on
    • 01:51nerves in the periphery
    • 01:53and sometimes they're done on
    • 01:55nerves closer to
    • 01:57the spinal cord. And that
    • 01:58doesn't mean that it's dangerous
    • 02:00because it's closer to the
    • 02:01spinal cord. It just means
    • 02:02that you're getting more nerve
    • 02:04coverage
    • 02:05the closer you get to
    • 02:06the source of the nerves.
    • 02:09So for laboring women, the
    • 02:10injection is around the low
    • 02:12back, and so it numbs
    • 02:14all the nerves from that
    • 02:15injection site and a little
    • 02:16bit above
    • 02:17down to the feet.
    • 02:21General anesthesia means that your
    • 02:23body is completely asleep. You're
    • 02:24not experiencing pain. What we
    • 02:26are doing is creating
    • 02:28a
    • 02:29space around both the brain
    • 02:31and the body which is
    • 02:32characterized
    • 02:32by unconsciousness,
    • 02:34analgesia,
    • 02:36amnesia
    • 02:36and paralysis
    • 02:38with the maintenance of physiologic
    • 02:39function.
    • 02:40And that physiologic function is
    • 02:42monitored and maintained
    • 02:44by your anesthesiologist
    • 02:45while you are as we
    • 02:46say sleeping.
    • 02:50Another type of anesthesia
    • 02:52is IV anesthesia,
    • 02:54which like general anesthesia,
    • 02:56it does afford one hypnosis
    • 02:59and level of numbness, but
    • 03:01usually you're not deep to
    • 03:03the point where you need
    • 03:04a breathing device for your
    • 03:06airway to be protected. This
    • 03:08is commonly seen
    • 03:09in cases like colonoscopies,
    • 03:11endoscopy,
    • 03:12or eye surgery.
    • 03:15Your basic physiology
    • 03:17is not only being maintained,
    • 03:19but an anesthesiologist
    • 03:21focusing on
    • 03:23you holistically
    • 03:24and helping to make sure
    • 03:26that you stay in good
    • 03:27balance.
    • 03:32One of the things that
    • 03:33we are seeing in anesthesia
    • 03:35is really a move towards
    • 03:36what we call a perioperative
    • 03:38home. Where patients are not
    • 03:40under the care of an
    • 03:41anesthesiologist
    • 03:42only during the immediate preoperative
    • 03:43and intraoperative period but really
    • 03:46becoming involved in care three
    • 03:47to six months prior to
    • 03:49a patient coming to surgery,
    • 03:50during surgery and then their
    • 03:52postoperative care afterwards.
    • 03:54And chronic pain medicine provides
    • 03:56an ability
    • 03:57to
    • 03:58attenuate risk factors for the
    • 03:59development of chronic pain after
    • 04:01surgery,
    • 04:02as well as to facilitate
    • 04:04the development
    • 04:05of comprehensive pain plans
    • 04:07to
    • 04:08minimize discomfort in the post
    • 04:10operative period both in and
    • 04:11out of the hospital.
    • 04:14It's a very exciting time
    • 04:15in anesthesia.
    • 04:17We're always
    • 04:18interrogating and really asking the
    • 04:20questions.
    • 04:21What does the data show?
    • 04:23So that we can do
    • 04:25this shared decision making with
    • 04:26our patients.
    • 04:28Anesthesiology
    • 04:29has become extraordinarily
    • 04:31safe,
    • 04:32both because of the monitoring
    • 04:34that we have, the medication
    • 04:36that we have, and the
    • 04:38vigilance
    • 04:39that we have.