Yale Institute for Global Health

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A Genetic Screen Identifies a New Master Regulator of Brain Metastasis
A new study from scientists at Yale School of Medicine has identified N-acetyltransferase 10 (NAT10), an enzyme highly expressed in brain metastasis, as a driver of brain metastasis. NAT10 primarily functions by adding acetyl groups to RNA molecules, regulating their function, stability or translation.
26 Mar 2025
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Protein Turnover Mapping May Offer Clues for Alzheimer’s, Cancer Treatment
Protein turnover is essential for cellular health. Yale researchers have now determined protein turnover across several tissue types, uncovering potential targets for treating Alzheimer’s disease and cancer.
20 Mar 2025
News
Cancer Metabolism Symposium
This inaugural event marked the launch of the Cancer Metabolism Initiative (CAMI), which aims to bring together investigators from across the campus to shape the future of cancer metabolism.
17 Nov 2023
News
Yale Scientists Receive $10.5M for ‘Team Science’ Exploration of Membrane Proteins in Their Natural Environment
An interdisciplinary team of Yale scientists is coming together to address crucial questions about how the cell membrane environment affects membrane proteins, with support from the National Institute of General Medical Sciences (NIGMS).
Source: Yale West Campus
28 Jun 2023
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The Roots of Biodiversity: How Proteins Differ Across Species
The traits of a particular species are not merely the result of its genes but also the proteins for which those genes code. Understanding the differences among species’ proteomes—or all of the proteins that can be expressed—is, therefore, as important as understanding differences among genomes.
Source: YaleNews
19 Sep 2022
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Study from Yale Cancer Biologists Identifies Chromatin Regulator WDR5 as Possible Drug Target in Triple-Negative Breast Cancer
A new study from Yale Cancer Center scientists has identified the chromatin regulator WDR5 as a possible new drug target in triple negative breast cancer.
31 Aug 2022
News
The Growth of the Cancer Biology Institute
Six years after laying out an ambitious blueprint for the Yale Cancer Biology Institute, much of it has been realized by recruiting scientists with unlimited potential and offering them their first labs. Led by Mark Lemmon, PhD, FRS, the institute has been built around young scientists he calls “superstars.”
30 Mar 2022
News
Study Finds Wide Variation Among Human Cell Lines Used for Research
One reason why an estimated 70% of researchers cannot reproduce other scientists' experiments may lie in significant differences in cell lines used by different laboratories, according to Yale researcher Yansheng Liu.
17 Feb 2019
News
Mass Spectrometry and Proteomics: Powerful Tools for Cancer Research
Advances in mass spectrometry and proteomics are giving researchers new ways to better understand, detect, diagnose, and treat cancer.
16 Jan 2019