2022
Pleiotropic MLLT10 variation confers risk of meningioma and estrogen-mediated cancers
Walsh KM, Zhang C, Calvocoressi L, Hansen HM, Berchuck A, Schildkraut JM, Bondy ML, Wrensch M, Wiemels JL, Claus EB. Pleiotropic MLLT10 variation confers risk of meningioma and estrogen-mediated cancers. Neuro-Oncology Advances 2022, 4: vdac044. PMID: 35702670, PMCID: PMC9187056, DOI: 10.1093/noajnl/vdac044.Peer-Reviewed Original ResearchRisk of meningiomaOvarian cancerBreast cancerER- breast cancerEstrogen receptor statusBody mass indexFemale breast cancerRisk of tumorsReceptor statusMass indexEstrogenic mechanismsHormonal factorsGenome-wide association studiesMeningiomasNormal meningesCancerMinor alleleCase-control datasetUK BiobankExpression quantitative trait lociMeningesRiskTumorsBreastAdiposity traits
2014
Endogenous and exogenous hormone exposure and the risk of meningioma in men.
Schildkraut JM, Calvocoressi L, Wang F, Wrensch M, Bondy ML, Wiemels JL, Claus EB. Endogenous and exogenous hormone exposure and the risk of meningioma in men. Journal Of Neurosurgery 2014, 120: 820-6. PMID: 24484233, PMCID: PMC4386752, DOI: 10.3171/2013.12.jns131170.Peer-Reviewed Original ResearchConceptsBody mass indexMeningioma riskOdds ratioHigher body mass indexExogenous hormone exposureMultivariate logistic regressionRelated risk factorsConfidence intervalsRisk of meningiomaPrevalence of exposureConsiderable morbidityMale patientsMass indexRisk factorsEndogenous estrogensReduced riskHormonal factorsHormone exposureIntracranial meningiomasExogenous exposureMeningiomasLogistic regressionUse of soyMenRisk