Developmental manganese neurotoxicity in rats: Cognitive deficits in allocentric and egocentric learning and memory
Amos-Kroohs RM, Davenport LL, Atanasova N, Abdulla ZI, Skelton MR, Vorhees CV, Williams MT. Developmental manganese neurotoxicity in rats: Cognitive deficits in allocentric and egocentric learning and memory. Neurotoxicology And Teratology 2016, 59: 16-26. PMID: 27756629, PMCID: PMC5235975, DOI: 10.1016/j.ntt.2016.10.005.Peer-Reviewed Original ResearchConceptsCognitive deficitsDevelopmental stressStriatal-dependent learningEgocentric learningMorris water mazeCA1 hippocampal long-term potentiationLong-term potentiationImpaired learningSpatial learningMnOEMemoryMultiple domainsSeparate offspringWater mazeIron-sufficient dietHippocampal long-term potentiationLearningU.S. childrenStandard beddingMazeDeficitsAllocentricMn overexposureChildrenSocio-economic areas