2001
Preoperative Anxiolysis and Postoperative Recovery in Women Undergoing Abdominal Hysterectomy
Kain Z, Sevarino F, Rinder C, Pincus S, Alexander G, Ivy M, Heninger G. Preoperative Anxiolysis and Postoperative Recovery in Women Undergoing Abdominal Hysterectomy. Anesthesiology 2001, 94: 415-422. PMID: 11374599, DOI: 10.1097/00000542-200103000-00009.Peer-Reviewed Original ResearchConceptsMorning of surgeryAbdominal hysterectomyPostoperative painAnalgesia useTreatment groupsGroup differencesLate postoperative time pointsPatient-controlled analgesia consumptionSelf-reported postoperative painPatient-controlled analgesia usePostoperative clinical courseTime pointsPostoperative time pointsMillions of patientsMinimal beneficial effectsLittle objective dataAnalgesic consumptionRecovery parametersAnalgesia consumptionIntramuscular midazolamPostoperative outcomesPostoperative periodPostoperative recoveryAbdominal surgeryClinical course
2000
Attenuation of the Preoperative Stress Response with Midazolam
Kain Z, Sevarino F, Pincus S, Alexander G, Wang S, Ayoub C, Kosarussavadi B. Attenuation of the Preoperative Stress Response with Midazolam. Anesthesiology 2000, 93: 141-147. PMID: 10861157, DOI: 10.1097/00000542-200007000-00024.Peer-Reviewed Original ResearchConceptsPlacebo groupTreatment groupsPostoperative anxietyPreoperative sedativesPreoperative stress responsePlacebo-controlled trialFirst postoperative weekGreater reductionGlobal health indexAnalgesic consumptionIbuprofen usePlacebo injectionsPostoperative painClinical recoveryIntramuscular midazolamSurgery lengthPain recoveryPostoperative weekAnesthetic techniqueGeneral anesthesiaOutpatient surgeryPreoperative outcomesClinical significanceMidazolamSurgery
1999
Preoperative Anxiety and Intraoperative Anesthetic Requirements
Maranets I, Kain Z. Preoperative Anxiety and Intraoperative Anesthetic Requirements. Anesthesia & Analgesia 1999, 89: 1346. DOI: 10.1213/00000539-199912000-00003.Peer-Reviewed Original ResearchConceptsIntraoperative anesthetic requirementsMaintenance of anesthesiaAnesthetic requirementsPropofol dosesPreoperative anxietyBaseline anxietyHypnotic componentAnesthetic stateIntraoperative propofol requirementsLaparoscopic tubal ligationCross-sectional studyHigh baseline anxietyAnxiety levelsBispectral index monitorMore propofolAnesthetic regimenIndependent predictorsPropofol requirementsInitial doseTubal ligationLarge dosesPatientsState anxietyAnxious patientsAnesthesiaPreoperative anxiety and intraoperative anesthetic requirements.
Maranets I, Kain Z. Preoperative anxiety and intraoperative anesthetic requirements. Anesthesia & Analgesia 1999, 89: 1346-51. PMID: 10589606, DOI: 10.1097/00000539-199912000-00003.Peer-Reviewed Original ResearchConceptsIntraoperative anesthetic requirementsTrait anxietyMaintenance of anesthesiaAnesthetic requirementsAnxiety levelsLow trait anxietyPropofol doseHigh trait anxietyLaparoscopic tubal ligationIntraoperative propofol requirementsAnesthetic stateDoses of anestheticsCross-sectional studyTubal ligationInitial doseBaseline anxietyAnxious patientsHypnotic componentState anxietyLarger dosesAnxietyInduction doseBispectral index monitoringPatientsDoseEstablishment of a pediatric surgery center: increasing anesthetic efficiency
Kain Z, Fasulo A, Rimar S. Establishment of a pediatric surgery center: increasing anesthetic efficiency. Journal Of Clinical Anesthesia 1999, 11: 540-544. PMID: 10624636, DOI: 10.1016/s0952-8180(99)00080-x.Peer-Reviewed Original ResearchEffect of peripheral perfusion on accuracy of pulse oximetry in children
Villanueva R, Bell C, Kain Z, Colingo K. Effect of peripheral perfusion on accuracy of pulse oximetry in children. Journal Of Clinical Anesthesia 1999, 11: 317-322. PMID: 10470634, DOI: 10.1016/s0952-8180(99)00054-9.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAnesthesia, GeneralBiasBlood PressureBody TemperatureBody WeightCatheterization, PeripheralChildChild, PreschoolEquipment DesignEsophagusForecastingHemoglobinsHumansInfantLaser-Doppler FlowmetryLinear ModelsOximetryOxygenProspective StudiesRadial ArteryRegional Blood FlowSkin TemperatureThermometersConceptsPerfusion variablesPulse oximetryPulse oximeterBackward multivariate linear regressionObservational clinical studyRadial artery catheterChildren 10 yearsLaser Doppler probeLarge university hospitalArterial pressureArtery catheterIndependent predictorsSystolic pressureGeneral anesthesiaPeripheral perfusionUniversity HospitalPulse pressureClinical studiesEffect of perfusionIntraarterial catheterLow perfusionDoppler probeDoppler readingsOhmeda 3700Total hemoglobinPostoperative Behavioral Outcomes in Children
Kain Z, Mayes L, Wang S, Hofstadter M. Postoperative Behavioral Outcomes in Children. Anesthesiology 1999, 90: 758-765. PMID: 10078677, DOI: 10.1097/00000542-199903000-00018.Peer-Reviewed Original ResearchConceptsPostoperative behavioral outcomesPostoperative day 1Induction of anesthesiaNegative behavioral changesPlacebo groupDay 1Multivariate logistic regression modelRecent stressful life eventsBehavioral changesFirst postoperative weekPostoperative behavioral changesPaucity of dataLogistic regression modelsPost Hospitalization Behavior QuestionnaireBehavioral outcomesMidazolam groupStressful life eventsPostoperative weekBehavioral recoveryIntervention groupPreoperative anxietyWeek 2Lower anxiety levelsSedative premedicationMeasures of anxietyPerioperative Information and Parental Anxiety
Kain Z. Perioperative Information and Parental Anxiety. Anesthesia & Analgesia 1999, 88: 237-239.. DOI: 10.1213/00000539-199902000-00001.Peer-Reviewed Original ResearchPerioperative information and parental anxiety: the next generation.
Kain Z. Perioperative information and parental anxiety: the next generation. Anesthesia & Analgesia 1999, 88: 237-9. PMID: 9972732, DOI: 10.1097/00000539-199902000-00001.Peer-Reviewed Original Research
1993
Anesthetic management of children with neuroblastoma
Kain Z, Shamberger R, Holzman R. Anesthetic management of children with neuroblastoma. Journal Of Clinical Anesthesia 1993, 5: 486-491. PMID: 8123275, DOI: 10.1016/0952-8180(93)90066-n.Peer-Reviewed Original ResearchMeSH KeywordsAbdominal NeoplasmsAnesthesia, GeneralAntineoplastic Combined Chemotherapy ProtocolsBlood Loss, SurgicalBlood PressureBostonChildChild, PreschoolCombined Modality TherapyFemaleHumansHypertensionInfantMaleMediastinal NeoplasmsMonitoring, IntraoperativeNeuroblastomaRetrospective StudiesTachycardiaConceptsHospital Medical CenterPosterior mediastinal massIntraoperative hypertensionMediastinal massSurgical proceduresLeft ventricular ejection fractionChildren's Hospital Medical CenterOptimal anesthetic regimenUrine catecholamine levelsType of chemotherapyVentricular ejection fractionPosterior mediastinal tumorVital sign changesAirway complicationsIntraoperative courseTracheal deviationAnesthetic regimenConsecutive childrenPostoperative dataAnesthetic managementBlood lossEjection fractionMediastinal tumorEchocardiographic examinationPleural effusion