2022
The role of parental health and distress in assessing children’s health status
Kaplan SH, Shaughnessy M, Fortier MA, Vivero-Montemayor M, Masague SG, Hayes D, Stern H, Dai M, Heim L, Kain Z. The role of parental health and distress in assessing children’s health status. Quality Of Life Research 2022, 31: 3403-3412. PMID: 35876948, PMCID: PMC9587925, DOI: 10.1007/s11136-022-03186-z.Peer-Reviewed Original ResearchMeSH KeywordsChildChild HealthChild, PreschoolHumansLongitudinal StudiesParentsQuality of LifeSelf ReportConceptsChild healthHealth statusFamily-centered pediatric careChild health statusPersonal healthParental distressEffective clinical managementQuality of lifeYoung children's healthPerioperative periodPediatric hospitalClinical managementGeneral healthPediatric careHealth settingsPoor personal healthHealth problemsPurposeThe purposeParental healthMental healthResultsOn averageBaseline dataLongitudinal studyParent-report measuresChildren
2001
Sensory Stimuli and Anxiety in Children Undergoing Surgery: A Randomized, Controlled Trial
Kain Z, Wang S, Mayes L, Krivutza D, Teague B. Sensory Stimuli and Anxiety in Children Undergoing Surgery: A Randomized, Controlled Trial. Anesthesia & Analgesia 2001, 92: 897-903. PMID: 11273921, DOI: 10.1097/00000539-200104000-00018.Peer-Reviewed Original ResearchConceptsInduction of anesthesiaChildren Undergoing SurgeryPostoperative day 1Postoperative behavioral changesSensory stimuliPost Hospitalization Behavior QuestionnaireUndergoing surgeryBehavioral recoveryIncreased complianceStimulation groupDay 1AnesthesiaControl groupAnesthesia maskOperating room lightsSurgeryAnxiety of childrenBehavioral interventionsOperating roomChildrenBehavioral changesExhibit low levelsBehavior QuestionnaireInductionAnxiety
2000
Social adaptability, cognitive abilities, and other predictors for children’s reactions to surgery
Kain Z, Mayes L, Weisman S, Hofstadter M. Social adaptability, cognitive abilities, and other predictors for children’s reactions to surgery. Journal Of Clinical Anesthesia 2000, 12: 549-554. PMID: 11137417, DOI: 10.1016/s0952-8180(00)00214-2.Peer-Reviewed Original ResearchConceptsCognitive abilitiesSocial adaptabilityParental anxietyPerioperative anxietyGroup of childrenChild temperamentChildren's reactionsAnxious parentsCorrelational analysisParental stateAdaptive behaviorPersonality characteristicsHigh intelligenceAnxietyAge 3TemperamentChildrenStylePredictorsSurgical childrenPersonalityAbilityRegression analysisHigh levelsIntelligenceMidazolam: Effects on Amnesia and Anxiety in Children
Kain Z, Hofstadter M, Mayes L, Krivutza D, Alexander G, Wang S, Reznick J. Midazolam: Effects on Amnesia and Anxiety in Children. Anesthesiology 2000, 93: 676. PMID: 10969300, DOI: 10.1097/00000542-200009000-00016.Peer-Reviewed Original ResearchMeSH KeywordsAmnesiaAnti-Anxiety AgentsAnxietyChildChild, PreschoolDouble-Blind MethodFemaleHumansMaleMemoryMental RecallMidazolamTime FactorsConceptsOral midazolamMidazolam administrationAnterograde amnesiaGood anterograde amnesiaSignificant anterograde amnesiaInduction of anesthesiaSignificant anxiolytic effectMidazolam groupGeneral anesthesiaSignificant group differencesAnxiolytic effectsBusy operating roomSurgical proceduresPostintervention testingDrug AdministrationControl groupMidazolamBaseline testingAnxiety measurement toolAnxiety of childrenOperating roomAdministrationGroup differencesPicture cardsAnesthesiaParental Presence and a Sedative Premedicant for Children Undergoing Surgery
Kain Z, Mayes L, Wang S, Caramico L, Krivutza D, Hofstadter M. Parental Presence and a Sedative Premedicant for Children Undergoing Surgery. Anesthesiology 2000, 92: 939-946. PMID: 10754612, DOI: 10.1097/00000542-200004000-00010.Peer-Reviewed Original ResearchConceptsPPIA groupSedative groupOverall careParental presenceParental satisfactionOperating roomParental anxietyInduction of anesthesiaPrimary endpointSecondary endpointsPerioperative periodOral midazolamOral sedativesPreoperative anxietySedative premedicantsAnesthesia maskChildrenSedativesAnxietyAdditive effectChild anxietyEndpointCareStandardized measuresInterventionPreoperative Anxiety and Postoperative Nausea and Vomiting in Children: Is There an Association?
Wang S, Kain Z. Preoperative Anxiety and Postoperative Nausea and Vomiting in Children: Is There an Association? Anesthesia & Analgesia 2000, 90: 571-575. PMID: 10702439, DOI: 10.1097/00000539-200003000-00014.Peer-Reviewed Original ResearchConceptsPostanesthesia care unitPostoperative nauseaPreoperative holding areaPreoperative anxietyOpioid consumptionPredictive valueMultivariate logistic regression modelAbsence of PONVOccurrence of PONVPerioperative opioid consumptionIncidence of nauseaOccurrence of nauseaAbsence of vomitingInduction of anesthesiaCross-sectional studyLogistic regression modelsChild anxietyHolding areaCare unitGeneral anesthesiaOutpatient surgeryPotential confoundersUnivariate analysisNauseaVomiting
1999
Establishment of a pediatric surgery center: increasing anesthetic efficiency
Kain Z, Fasulo A, Rimar S. Establishment of a pediatric surgery center: increasing anesthetic efficiency. Journal Of Clinical Anesthesia 1999, 11: 540-544. PMID: 10624636, DOI: 10.1016/s0952-8180(99)00080-x.Peer-Reviewed Original ResearchEffect of peripheral perfusion on accuracy of pulse oximetry in children
Villanueva R, Bell C, Kain Z, Colingo K. Effect of peripheral perfusion on accuracy of pulse oximetry in children. Journal Of Clinical Anesthesia 1999, 11: 317-322. PMID: 10470634, DOI: 10.1016/s0952-8180(99)00054-9.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAnesthesia, GeneralBiasBlood PressureBody TemperatureBody WeightCatheterization, PeripheralChildChild, PreschoolEquipment DesignEsophagusForecastingHemoglobinsHumansInfantLaser-Doppler FlowmetryLinear ModelsOximetryOxygenProspective StudiesRadial ArteryRegional Blood FlowSkin TemperatureThermometersConceptsPerfusion variablesPulse oximetryPulse oximeterBackward multivariate linear regressionObservational clinical studyRadial artery catheterChildren 10 yearsLaser Doppler probeLarge university hospitalArterial pressureArtery catheterIndependent predictorsSystolic pressureGeneral anesthesiaPeripheral perfusionUniversity HospitalPulse pressureClinical studiesEffect of perfusionIntraarterial catheterLow perfusionDoppler probeDoppler readingsOhmeda 3700Total hemoglobinDistress During the Induction of Anesthesia and Postoperative Behavioral Outcomes
Kain Z, Wang S, Mayes L, Caramico L, Hofstadter M. Distress During the Induction of Anesthesia and Postoperative Behavioral Outcomes. Anesthesia & Analgesia 1999, 88: 1042-1047.. DOI: 10.1213/00000539-199905000-00013.Peer-Reviewed Original ResearchDistress during the induction of anesthesia and postoperative behavioral outcomes.
Kain Z, Wang S, Mayes L, Caramico L, Hofstadter M. Distress during the induction of anesthesia and postoperative behavioral outcomes. Anesthesia & Analgesia 1999, 88: 1042-7. PMID: 10320165, DOI: 10.1097/00000539-199905000-00013.Peer-Reviewed Original ResearchPostoperative Behavioral Outcomes in Children
Kain Z, Mayes L, Wang S, Hofstadter M. Postoperative Behavioral Outcomes in Children. Anesthesiology 1999, 90: 758-765. PMID: 10078677, DOI: 10.1097/00000542-199903000-00018.Peer-Reviewed Original ResearchConceptsPostoperative behavioral outcomesPostoperative day 1Induction of anesthesiaNegative behavioral changesPlacebo groupDay 1Multivariate logistic regression modelRecent stressful life eventsBehavioral changesFirst postoperative weekPostoperative behavioral changesPaucity of dataLogistic regression modelsPost Hospitalization Behavior QuestionnaireBehavioral outcomesMidazolam groupStressful life eventsPostoperative weekBehavioral recoveryIntervention groupPreoperative anxietyWeek 2Lower anxiety levelsSedative premedicationMeasures of anxiety
1998
Preoperative Preparation Programs in Children
Kain Z, Caramico L, Mayes L, Genevro J, Bornstein M, Hofstadter M. Preoperative Preparation Programs in Children. Anesthesia & Analgesia 1998, 87: 1249-1255.. DOI: 10.1213/00000539-199812000-00007.Peer-Reviewed Original ResearchPreoperative preparation programs in children: a comparative examination.
Kain Z, Caramico L, Mayes L, Genevro J, Bornstein M, Hofstadter M. Preoperative preparation programs in children: a comparative examination. Anesthesia & Analgesia 1998, 87: 1249-55. PMID: 9842807, DOI: 10.1097/00000539-199812000-00007.Peer-Reviewed Original ResearchParental Presence during Induction of Anesthesia versus Sedative Premedication
Kain Z, Mayes L, Wang S, Caramico L, Hofstadter M. Parental Presence during Induction of Anesthesia versus Sedative Premedication. Anesthesiology 1998, 89: 1147-1156. PMID: 9822003, DOI: 10.1097/00000542-199811000-00015.Peer-Reviewed Original ResearchConceptsInduction of anesthesiaMidazolam groupControl groupParental presenceOral midazolamEnd pointParental presence groupPrimary end pointSecondary end pointsParental anxiety scoresPerioperative periodPreoperative periodPreoperative anxietySedative premedicationAnesthesia maskAnesthesiaMidazolamOperating roomAnxiety scoresParent anxietyChildrenLess anxietyInterventionAnxietyInduction
1997
The Yale Preoperative Anxiety Scale: How Does It Compare with a "Gold Standard"?
Kain Z, Mayes L, Cicchetti D, Bagnall A, Finley J, Hofstadter M. The Yale Preoperative Anxiety Scale: How Does It Compare with a "Gold Standard"? Anesthesia & Analgesia 1997, 85: 783. DOI: 10.1213/00000539-199710000-00012.Peer-Reviewed Original ResearchThe Yale Preoperative Anxiety Scale
Kain Z, Mayes L, Cicchetti D, Bagnall A, Finley J, Hofstadter M. The Yale Preoperative Anxiety Scale. Anesthesia & Analgesia 1997, 85: 783-788.. PMID: 9322455, DOI: 10.1097/00000539-199710000-00012.Peer-Reviewed Original ResearchPremedication in the United States: A Status Report
Kain Z, Mayes L, Bell C, Weisman S, Hofstadter M, Rimar S. Premedication in the United States: A Status Report. Anesthesia & Analgesia 1997, 84: 427. DOI: 10.1213/00000539-199702000-00035.Peer-Reviewed Original ResearchConceptsSedative premedicationUse of premedicationHealth maintenance organization (HMO) penetrationYears of ageAge 3 yearsIndependent predictorsMultivariable analysisAnesthetic careSedative drugsPremedicationPhysician membersSedative premedicantsAge groupsLack of consensusPremedicantAdultsAmerican SocietyAnesthesiologistsHMO penetrationChildrenHMO participationUnited StatesSurvey studyMarked variationQuestionnairePremedication in the United States
Kain Z, Mayes L, Bell C, Weisman S, Hofstadter M, Rimar S. Premedication in the United States. Anesthesia & Analgesia 1997, 84: 427-432.. PMID: 9024042, DOI: 10.1097/00000539-199702000-00035.Peer-Reviewed Original ResearchConceptsSedative premedicationUse of premedicationHealth maintenance organization (HMO) penetrationYears of ageAge 3 yearsIndependent predictorsMultivariable analysisAnesthetic careSedative drugsPremedicationPhysician membersSedative premedicantsAge groupsLack of consensusPremedicantAdultsAmerican SocietyAnesthesiologistsHMO penetrationChildrenHMO participationUnited StatesSurvey studyMarked variationQuestionnaire
1996
Preoperative preparation in children: A cross-sectional study
Kain Z, Mayes L, Caramico L. Preoperative preparation in children: A cross-sectional study. Journal Of Clinical Anesthesia 1996, 8: 508-514. PMID: 8872693, DOI: 10.1016/0952-8180(96)00115-8.Peer-Reviewed Original ResearchConceptsCross-sectional studyPrevious hospitalizationPreoperative preparation programChild's ageMultivariable regression analysisAnxiety responsesPediatric outpatientsElective surgeryIndependent predictorsChildren's HospitalOutpatient surgeryPreoperative preparationAge of childrenPreoperative programSurgeryOperating roomOverall anxietyAgeHospitalizationChildrenRegression analysisHospitalPredictorsAnxietyInterventionParental Presence during Induction of Anesthesia
Kain Z, Mayes L, Caramico L, Silver D, Spieker M, Nygren M, Anderson G, Rimar S. Parental Presence during Induction of Anesthesia. Anesthesiology 1996, 84: 1060-1067. PMID: 8623999, DOI: 10.1097/00000542-199605000-00007.Peer-Reviewed Original ResearchConceptsInduction of anesthesiaSerum cortisol concentrationsLow baseline levelsParental presencePhysiologic measuresBaseline levelsCortisol concentrationsPreoperative behavioral interventionsMultivariate linear regression analysisOutpatient surgeryIntervention groupLinear regression analysisControl groupParent-absent groupBaseline temperamentAnesthesiaBehavioral interventionsChild's ageSignificant differencesChildrenRegression analysisInterventionLow trait anxietyTrait anxietyAnxiety