2024
Auricular laser acupuncture as an adjunct for parental anxiety management during children's surgery: A randomized‐controlled study
Lin W, Fortier M, Cortes H, Kain Z, Wang S, Li G. Auricular laser acupuncture as an adjunct for parental anxiety management during children's surgery: A randomized‐controlled study. Pediatric Anesthesia 2024, 34: 1231-1239. PMID: 39291464, DOI: 10.1111/pan.14998.Peer-Reviewed Original ResearchPost-interventionParents of childrenSham acupunctureAuricular acupunctureLaser acupunctureRepeated-measures analysis of variancePlacebo control groupAnalysis of varianceRepeated-measures analysisParental anxiety managementControl groupAcupuncture systemAcupunctureIntervention groupPre-interventionRandomized-controlled studySelf-reported anxietyAssociated with higher levelsParent-reported anxietyChildren's surgeryNo adverse eventsAnxiety managementMitigate anxietyAnxiety levelsBaseline data
2001
Sensory Stimuli and Anxiety in Children Undergoing Surgery: A Randomized, Controlled Trial
Kain Z, Wang S, Mayes L, Krivutza D, Teague B. Sensory Stimuli and Anxiety in Children Undergoing Surgery: A Randomized, Controlled Trial. Anesthesia & Analgesia 2001, 92: 897-903. PMID: 11273921, DOI: 10.1097/00000539-200104000-00018.Peer-Reviewed Original ResearchConceptsInduction of anesthesiaChildren Undergoing SurgeryPostoperative day 1Postoperative behavioral changesSensory stimuliPost Hospitalization Behavior QuestionnaireUndergoing surgeryBehavioral recoveryIncreased complianceStimulation groupDay 1AnesthesiaControl groupAnesthesia maskOperating room lightsSurgeryAnxiety of childrenBehavioral interventionsOperating roomChildrenBehavioral changesExhibit low levelsBehavior QuestionnaireInductionAnxiety
2000
Midazolam: Effects on Amnesia and Anxiety in Children
Kain Z, Hofstadter M, Mayes L, Krivutza D, Alexander G, Wang S, Reznick J. Midazolam: Effects on Amnesia and Anxiety in Children. Anesthesiology 2000, 93: 676. PMID: 10969300, DOI: 10.1097/00000542-200009000-00016.Peer-Reviewed Original ResearchConceptsOral midazolamMidazolam administrationAnterograde amnesiaGood anterograde amnesiaSignificant anterograde amnesiaInduction of anesthesiaSignificant anxiolytic effectMidazolam groupGeneral anesthesiaSignificant group differencesAnxiolytic effectsBusy operating roomSurgical proceduresPostintervention testingDrug AdministrationControl groupMidazolamBaseline testingAnxiety measurement toolAnxiety of childrenOperating roomAdministrationGroup differencesPicture cardsAnesthesia
1999
An alternative method to alleviate postoperative nausea and vomiting in children
Wang S, Hofstadter M, Kain Z. An alternative method to alleviate postoperative nausea and vomiting in children. Journal Of Clinical Anesthesia 1999, 11: 231-234. PMID: 10434220, DOI: 10.1016/s0952-8180(99)00035-5.Peer-Reviewed Original ResearchConceptsPostoperative nauseaGeneral anesthesiaTreatment groupsControl groupASA physical status IPediatric surgery centersPhysical status IElective outpatient surgeryVisual analog scaleChildren ages 6Intravenous ondansetronAntiemetic effectRescue therapyStatus IRecurrent nauseaAnalog scaleOutpatient surgerySurgery centersNauseaVomitingEffective treatmentTreatment sequenceAge 6SurgeryAnesthesia
1998
Parental Presence during Induction of Anesthesia versus Sedative Premedication
Kain Z, Mayes L, Wang S, Caramico L, Hofstadter M. Parental Presence during Induction of Anesthesia versus Sedative Premedication. Anesthesiology 1998, 89: 1147-1156. PMID: 9822003, DOI: 10.1097/00000542-199811000-00015.Peer-Reviewed Original ResearchConceptsInduction of anesthesiaMidazolam groupControl groupParental presenceOral midazolamEnd pointParental presence groupPrimary end pointSecondary end pointsParental anxiety scoresPerioperative periodPreoperative periodPreoperative anxietySedative premedicationAnesthesia maskAnesthesiaMidazolamOperating roomAnxiety scoresParent anxietyChildrenLess anxietyInterventionAnxietyInduction
1997
Parental Desire for Perioperative Information and Informed Consent: A Two-Phase Study
Kain Z, Wang S, Caramico L, Hofstadter M, Mayes L. Parental Desire for Perioperative Information and Informed Consent: A Two-Phase Study. Anesthesia & Analgesia 1997, 84: 299. DOI: 10.1213/00000539-199702000-00011.Peer-Reviewed Original ResearchConceptsPerioperative informationPerioperative periodParents of childrenParental anxietyTime pointsDay of surgeryCross-sectional studyParental anxiety levelsRisk informationPhase 2Phase 1Majority of parentsParental educational levelIntervention groupPossible complicationsControl groupInformed consentSurgeryOperating roomGroup assignmentTwo-phase studyAnxiety levelsSignificant differencesInterventionEducational levelParental Desire for Perioperative Information and Informed Consent
Kain Z, Wang S, Caramico L, Hofstadter M, Mayes L. Parental Desire for Perioperative Information and Informed Consent. Anesthesia & Analgesia 1997, 84: 299-306.. PMID: 9024018, DOI: 10.1097/00000539-199702000-00011.Peer-Reviewed Original ResearchConceptsPerioperative informationPerioperative periodParents of childrenParental anxietyTime pointsDay of surgeryCross-sectional studyParental anxiety levelsRisk informationPhase 2Phase 1Majority of parentsParental educational levelIntervention groupPossible complicationsControl groupInformed consentSurgeryOperating roomGroup assignmentAnxiety levelsSignificant differencesInterventionEducational levelInformation parents
1996
Parental Presence during Induction of Anesthesia
Kain Z, Mayes L, Caramico L, Silver D, Spieker M, Nygren M, Anderson G, Rimar S. Parental Presence during Induction of Anesthesia. Anesthesiology 1996, 84: 1060-1067. PMID: 8623999, DOI: 10.1097/00000542-199605000-00007.Peer-Reviewed Original ResearchConceptsInduction of anesthesiaSerum cortisol concentrationsLow baseline levelsParental presencePhysiologic measuresBaseline levelsCortisol concentrationsPreoperative behavioral interventionsMultivariate linear regression analysisOutpatient surgeryIntervention groupLinear regression analysisControl groupParent-absent groupBaseline temperamentAnesthesiaBehavioral interventionsChild's ageSignificant differencesChildrenRegression analysisInterventionLow trait anxietyTrait anxietyAnxiety