2000
Cloning and Characterization of the Murine Pkd2 Promoter
Park J, Li L, Cai Y, Hayashi T, Dong F, Maeda Y, Rubin C, Somlo S, Wu G. Cloning and Characterization of the Murine Pkd2 Promoter. Genomics 2000, 66: 305-312. PMID: 10873385, DOI: 10.1006/geno.2000.6197.Peer-Reviewed Original ResearchAnimalsBase SequenceCell LineCloning, MolecularCodon, InitiatorExonsGene Expression RegulationHumansIntronsMembrane ProteinsMiceMutagenesis, Site-DirectedPolycystic Kidney, Autosomal DominantPromoter Regions, GeneticSequence DeletionSequence Homology, Nucleic AcidTranscription, GeneticTransfectionTRPP Cation Channels
1997
Characterization of the Exon Structure of the Polycystic Kidney Disease 2 Gene (PKD2)
Hayashi T, Mochizuki T, Reynolds D, Wu G, Cai Y, Somlo S. Characterization of the Exon Structure of the Polycystic Kidney Disease 2 Gene (PKD2). Genomics 1997, 44: 131-136. PMID: 9286709, DOI: 10.1006/geno.1997.4851.Peer-Reviewed Original ResearchConceptsAG/GT rulePolycystic kidney disease 2 (PKD2) geneExon-intron structureIntegral membrane proteinsAutosomal dominant polycystic kidney diseaseTranslation start siteExon structurePositional cloningMembrane proteinsStart siteGenomic DNASplice acceptorPKD2 geneGenesExon 1Oligonucleotide primersHeteroduplex analysisPKD2Dominant polycystic kidney diseasePolycystic kidney diseaseMutation analysisCalcium channelsCloningSecond formExons