2013
MicroRNAs as pharmacological targets in endothelial cell function and dysfunction
Chamorro-Jorganes A, Araldi E, Suárez Y. MicroRNAs as pharmacological targets in endothelial cell function and dysfunction. Pharmacological Research 2013, 75: 15-27. PMID: 23603154, PMCID: PMC3752325, DOI: 10.1016/j.phrs.2013.04.002.Peer-Reviewed Original ResearchConceptsEndothelial cell functionShort non-coding RNAsCell functionPost-transcriptional levelNon-coding RNAsEndothelial-specific microRNAsGene expressionMorphogenic capacityCritical regulatorNormal endothelial cell functionMicroRNAsCell dysfunctionEndothelial cell dysfunctionPathophysiological conditionsLatest insightsParacrine mannerPharmacological targetsEndothelial cellsTherapeutic potentialBarrier functionTraffickingRNALeukocyte traffickingRegulatorTarget
2009
MicroRNAs As Novel Regulators of Angiogenesis
Suárez Y, Sessa WC. MicroRNAs As Novel Regulators of Angiogenesis. Circulation Research 2009, 104: 442-454. PMID: 19246688, PMCID: PMC2760389, DOI: 10.1161/circresaha.108.191270.Peer-Reviewed Original ResearchConceptsInvolvement of miRNAsShort noncoding RNAsPosttranscriptional regulationNoncoding RNAsNovel regulatorKey regulatorNegative regulatorGene expressionAspects of developmentNew blood vesselsRegulatorVascular biologyCurrent experimental evidencePotential therapeutic applicationsMiRNAsMicroRNAsAngiogenic processEndothelial cellsRegulationAbnormal angiogenesisTherapeutic applicationsAngiogenesisRNABiologyHomeostasis