2017
Response from Original Authors - RE: Six novel rare nonsynonymous mutations for migraine without aura identified by exome sequencing
Wang XP, Xu ZX, Sun XJ, Luo X. Response from Original Authors - RE: Six novel rare nonsynonymous mutations for migraine without aura identified by exome sequencing. Journal Of Neurogenetics 2017, 31: 322-324. PMID: 29037100, DOI: 10.1080/01677063.2017.1382491.Peer-Reviewed Original Research
2015
Six novel rare non-synonymous mutations for migraine without aura identified by exome sequencing
Jiang Y, Wu R, Chen C, You ZF, Luo X, Wang XP. Six novel rare non-synonymous mutations for migraine without aura identified by exome sequencing. Journal Of Neurogenetics 2015, 29: 188-194. PMID: 26814133, DOI: 10.3109/01677063.2015.1122787.Peer-Reviewed Original ResearchMeSH KeywordsCalcium-Binding ProteinsChloride ChannelsComputational BiologyDNA Mutational AnalysisExomeFamily HealthFemaleGenetic Association StudiesGenetic Predisposition to DiseaseGTPase-Activating ProteinsGTP-Binding ProteinsHumansMaleMembrane GlycoproteinsMigraine without AuraMucinsMutationPolymorphism, Single NucleotideReceptors, G-Protein-CoupledUbiquitin-Conjugating EnzymesXedar ReceptorConceptsNon-synonymous mutationsRare non-synonymous mutationsExome sequencingNovel non-synonymous mutationsBioinformatics analysisX chromosomeMultiple genesCellular responsesWhole-exome sequencingSusceptibility gene mutationsCell membrane potentialARHGAP28MutationsSequencingProteinGBP2Membrane potentialEMR1Gene mutationsChemical factorsCLCNKBChromosomesGenesVasogenic theoryGenetic predisposition
2013
Exome-wide association study of replicable nonsynonymous variants conferring risk for alcohol dependence.
Zuo L, Saba L, Wang K, Zhang X, Krystal JH, Tabakoff B, Luo X. Exome-wide association study of replicable nonsynonymous variants conferring risk for alcohol dependence. Journal Of Studies On Alcohol And Drugs 2013, 74: 622-5. PMID: 23739027, PMCID: PMC3711352, DOI: 10.15288/jsad.2013.74.622.Peer-Reviewed Original ResearchConceptsApolipoprotein E receptor 2Risk genesNonsynonymous variantsRNA expression analysisExome-wide association studyE receptor 2Expression analysisAssociation studiesGenesWhole exomeProtein 2RNA expressionNsSNPReplicable associationsAlcohol dependenceNonhuman speciesEuropean American sampleReceptor 2UbiquitinVariantsMultiple testingSpeciesExomeBioinformaticsUBAP2