2022
Childhood trauma and cognitive deficits in patients with schizophrenia: mediation by orbitofrontal cortex H-shaped sulci volume
Wang L, Yin Y, Feng W, Zhou Y, Huang J, Zhang P, Chen S, Fan H, Cui Y, Luo X, Tan S, Wang Z, Tian B, Tian L, Li CR, Tan Y. Childhood trauma and cognitive deficits in patients with schizophrenia: mediation by orbitofrontal cortex H-shaped sulci volume. Journal Of Psychiatry And Neuroscience 2022, 47: e209-e217. PMID: 35654451, PMCID: PMC9177195, DOI: 10.1503/jpn.210178.Peer-Reviewed Original ResearchConceptsFirst-episode schizophreniaCTQ total scoresHealthy controlsCognitive functionChildhood Trauma QuestionnaireTotal scoreCognitive deficitsChildhood trauma experiencesMATRICS Consensus Cognitive BatteryChildhood traumaOrbitofrontal cortexWorse cognitive functionTrauma experiencesHigh-resolution MRIRetrospective designPatientsConsensus Cognitive BatterySchizophreniaTraumaSubscoresSmall sample sizeTrauma QuestionnaireComposite scoreLines of evidenceScores
2021
Kynurenine metabolism and metabolic syndrome in patients with schizophrenia
Zhang P, Huang J, Gou M, Zhou Y, Tong J, Fan F, Cui Y, Luo X, Tan S, Wang Z, Yang F, Tian B, Li CR, Hong LE, Tan Y. Kynurenine metabolism and metabolic syndrome in patients with schizophrenia. Journal Of Psychiatric Research 2021, 139: 54-61. PMID: 34034146, DOI: 10.1016/j.jpsychires.2021.05.004.Peer-Reviewed Original ResearchConceptsMetabolic syndromeKP metabolitesMS scorePathogenesis of MSKynurenine pathway metabolismRegression analysisKynurenine metabolismPatient groupHealthy controlsMultiple linear regression analysisSchizophrenia patientsLinear regression analysisPathway metabolismPatientsContributory roleSchizophreniaHigh nicotinamide adenine dinucleotideNicotinamide adenine dinucleotideMS factorsPotential rolePartial correlation analysisScoresMultiple regression analysisSyndromePathogenesis
2018
Principal component analysis of early alcohol, drug and tobacco use with major depressive disorder in US adults
Wang K, Liu Y, Ouedraogo Y, Wang N, Xie X, Xu C, Luo X. Principal component analysis of early alcohol, drug and tobacco use with major depressive disorder in US adults. Journal Of Psychiatric Research 2018, 100: 113-120. PMID: 29518578, PMCID: PMC6329582, DOI: 10.1016/j.jpsychires.2018.02.022.Peer-Reviewed Original ResearchConceptsMajor depressive disorderDrug useEarly alcoholDepressive disorderOdds ratioAdult major depressive disorderMultiple logistic regression analysisConfidence intervalsMultiple logistic regressionLogistic regression analysisOverall prevalenceTobacco useUS adultsSignificant associationLogistic regressionRegression analysisNational surveyDisordersAdultsPotential factorsScoresAssociationTobaccoYearsPast year