2023
Serum BDNF levels and state anxiety are associated with somatic symptoms in patients with panic disorder
Li J, Li R, Li D, Zhang J, Luo X, Zhang Y. Serum BDNF levels and state anxiety are associated with somatic symptoms in patients with panic disorder. Frontiers In Psychiatry 2023, 14: 1168771. PMID: 37533888, PMCID: PMC10393281, DOI: 10.3389/fpsyt.2023.1168771.Peer-Reviewed Original ResearchPanic Disorder Severity Scale-Chinese VersionSerum BDNF levelsState-Trait Anxiety InventoryBDNF levelsSomatic symptomsPanic disorderPHQ-15State anxietyPD patientsSerum BDNFBaseline serum BDNF levelsHealthy controlsAssociated with somatic symptomsAnxiety-related symptomsAnxiety-related variablesMeasure somatic symptomsPHQ-15 scoresEscitalopram treatmentPanic severityAssess panicNinety PD patientsState-TraitAnxiety InventoryPanicPartial correlation analysisSerum BDNF levels are involved in the diagnosis and treatment response in patients with PD
Li R, Li J, Liu Y, Li D, Chu L, Zhang J, Luo X, Zhang Y. Serum BDNF levels are involved in the diagnosis and treatment response in patients with PD. Journal Of Affective Disorders 2023, 327: 31-37. PMID: 36739005, DOI: 10.1016/j.jad.2023.01.107.Peer-Reviewed Original ResearchConceptsBaseline serum BDNF levelsSerum BDNF levelsBrain-derived neurotrophic factorState-Trait Anxiety InventoryBDNF levelsPanic disorderTrait anxietyHAMA-14PD patientsHealthy controlsBrain-derived neurotrophic factor serum levelsDiagnosis of panic disorderTreatment response to escitalopramHamilton Anxiety Rating ScaleResponse to escitalopramAnxiety Rating ScaleTreatment responseEscitalopram treatmentAnxiety symptomsNeuropsychological testsNinety PD patientsState-TraitAnxiety InventoryRating ScaleWeeks of treatmentAn Update on Nondopaminergic Treatments for Motor and Non-motor Symptoms of Parkinson’s Disease
Jing XZ, Yuan XZ, Luo X, Zhang SY, Wang XP. An Update on Nondopaminergic Treatments for Motor and Non-motor Symptoms of Parkinson’s Disease. Current Neuropharmacology 2023, 21: 1806-1826. PMID: 35193486, PMCID: PMC10514518, DOI: 10.2174/1570159x20666220222150811.Peer-Reviewed Original ResearchConceptsNon-motor symptomsDopamine replacement therapyPD patientsMotor fluctuationsParkinson's diseaseNondopaminergic treatmentsReplacement therapyCertain non-motor symptomsTraditional dopamine replacement therapyLower urinary tract symptomsUrinary tract symptomsOngoing clinical trialsPotential adverse eventsManagement of motorPositive clinical implicationsManagement of hallucinationsDopaminergic strategiesMotor complicationsNondopaminergic drugsPD psychosisOrthostatic hypotensionTract symptomsAdverse eventsClinical benefitClinical efficacy
2021
Pharmacological and Non-pharmacological Treatments of Sleep Disorders in Parkinson's Disease
Taximaimaiti R, Luo X, Wang XP. Pharmacological and Non-pharmacological Treatments of Sleep Disorders in Parkinson's Disease. Current Neuropharmacology 2021, 19: 2233-2249. PMID: 33998990, PMCID: PMC9185775, DOI: 10.2174/1570159x19666210517115706.Peer-Reviewed Original ResearchConceptsNon-pharmacological treatmentExcessive daytime sleepinessRestless legs syndromeRapid eye movementSleep disordersParkinson's diseaseSide effectsCommon non-motor symptomSleep behavior disorderNon-motor symptomsCommon sleep disorderDeep brain stimulationSleep hygiene educationRelative side effectsQuality of lifeCognitive behavior therapyLegs syndromePD patientsPharmacological treatmentComplementary therapiesDaytime sleepinessSleep qualityBrain stimulationBehavior disorderDisease
2020
Associations between brain‐derived neurotrophic factor and cognitive impairment in panic disorder
Wang W, Liu Y, Luo S, Guo X, Luo X, Zhang Y. Associations between brain‐derived neurotrophic factor and cognitive impairment in panic disorder. Brain And Behavior 2020, 10: e01885. PMID: 33047489, PMCID: PMC7749616, DOI: 10.1002/brb3.1885.Peer-Reviewed Original ResearchConceptsBDNF Met/Met genotypeMet/Met genotypeLower BDNF plasma levelsPanic disorderCognitive impairmentMet genotypeMontreal Cognitive AssessmentStroop interferenceVerbal learningNeurocognitive measuresCognitive performanceBDNF plasma levelsMoCA dataCognitive AssessmentAnxiety ScaleBDNF Val66Met polymorphismVal/ValPanic symptomsLower scoresPD patientsHamilton Anxiety ScaleProcessing domainPlasma levelsHealthy controlsModerate positive correlation