Sex differences of gray matter morphology in cortico-limbic-striatal neural system in major depressive disorder
Kong L, Chen K, Womer F, Jiang W, Luo X, Driesen N, Liu J, Blumberg H, Tang Y, Xu K, Wang F. Sex differences of gray matter morphology in cortico-limbic-striatal neural system in major depressive disorder. Journal Of Psychiatric Research 2013, 47: 733-739. PMID: 23453566, PMCID: PMC3626116, DOI: 10.1016/j.jpsychires.2013.02.003.Peer-Reviewed Original ResearchConceptsMajor depressive disorderHealthy controlsGray matter morphologyDepressive disorderPrefrontal cortexSex differencesHigh-resolution structural magnetic resonanceSignificant GM reductionsFemale healthy controlsLeft ventral prefrontal cortexStructural magnetic resonanceNeural systemsVentral prefrontal cortexClinical presentationLimbic regionsMedication-naïve participantsClinical aspectsRight hippocampusStriatal regionsBilateral caudateRight amygdalaHC groupGM reductionSex-related patternsMDD females