N-Methyl-d-Aspartate Receptor Antibody and Sensory Gating Deficits in Non-smoking, Minimal Antipsychotic Medication Exposure, and First-Episode Patients With Schizophrenia
Tong J, Yang K, Li W, Wang L, Yin Y, Zhou Y, Huang J, Zhang P, Zhao Y, Chen S, Fan H, Cui Y, Luo X, Tan S, Wang Z, Feng W, Tian B, Li C, Hong L, Tan Y. N-Methyl-d-Aspartate Receptor Antibody and Sensory Gating Deficits in Non-smoking, Minimal Antipsychotic Medication Exposure, and First-Episode Patients With Schizophrenia. Schizophrenia Bulletin 2024, sbae180. PMID: 39406395, DOI: 10.1093/schbul/sbae180.Peer-Reviewed Original ResearchFirst-episode schizophreniaSensory gating deficitsN-methyl-D-aspartate receptorsFirst-episode schizophrenia groupGating deficitsN-methyl-D-aspartateP50 ratioSensory gatingExposure to antipsychotic medicationAb levelsHealthy controlsAntipsychotic medication exposureFirst-episode patientsDiagnosis of schizophreniaImpaired sensory gatingP50 sensory gating deficitN-methyl-D-aspartate receptor antibodiesAntipsychotic medicationFirst-episodeNon-smoking healthy controlsP50 differenceSchizophreniaPartial correlation analysisEnzyme-linked immunosorbent assayDeficitsDoes Baseline Cognitive Function Predict the Reduction Rate in HDRS-17 Total Scores in First-Episode, Drug-Naïve Patients with Major Depressive Disorder?
Jiao Q, Dong Y, Ma X, Ji S, Liu X, Zhang J, Sun X, Li D, Luo X, Zhang Y. Does Baseline Cognitive Function Predict the Reduction Rate in HDRS-17 Total Scores in First-Episode, Drug-Naïve Patients with Major Depressive Disorder? Neuropsychiatric Disease And Treatment 2024, 20: 353-361. PMID: 38415074, PMCID: PMC10898600, DOI: 10.2147/ndt.s453447.Peer-Reviewed Original ResearchHDRS-17 total scoreFunctioning Assessment Short TestMATRICS Consensus Cognitive BatteryMajor depressive disorderHDRS-17FED patientsCPT-IPCognitive functionBaseline cognitive functionTotal scoreDepressive disorderFirst-episodeDrug-naivePatients' responses to antidepressant treatmentFunctioning Assessment Short Test total scoreResponse to antidepressant treatmentHamilton Depression Rating ScaleFunctioning Assessment Short Test scoreConsensus Cognitive BatteryDepression Rating ScaleAssociated with worse cognitive functionSpeed of processingHamilton Anxiety ScaleDrug-naive patientsInterpersonal relationship domain