2016
CHRNA4 was associated with prepulse inhibition of schizophrenia in Chinese: a pilot study
Shi J, Wang Z, Tan Y, Fan H, An H, Zuo L, Yang F, Tan S, Li J, Zhang X, Zhou D, Luo X. CHRNA4 was associated with prepulse inhibition of schizophrenia in Chinese: a pilot study. Cognitive Neuropsychiatry 2016, 21: 156-167. PMID: 26982087, DOI: 10.1080/13546805.2016.1155437.Peer-Reviewed Original ResearchConceptsMs prepulse intervalsSingle nucleotide polymorphismsAuditory startle reflexCentral nervous systemPotential endophenotypePrepulse intervalsPrepulse inhibitionSensorimotor gatingTT genotypeGG genotypeNervous systemStartle reflexSchizophreniaPilot studyPPI levelsCHRNA4PatientsNucleotide polymorphismsCurrent studyIndependent replicationInhibitionEndophenotypesLow levelsPPIPolymorphism
2015
Genetic variants in the CPNE5 gene are associated with alcohol dependence and obesity in Caucasian populations
Wang KS, Zuo L, Pan Y, Xie C, Luo X. Genetic variants in the CPNE5 gene are associated with alcohol dependence and obesity in Caucasian populations. Journal Of Psychiatric Research 2015, 71: 1-7. PMID: 26522866, DOI: 10.1016/j.jpsychires.2015.09.008.Peer-Reviewed Original ResearchConceptsAlcohol dependenceSingle nucleotide polymorphismsMultiple logistic regression analysisMarshfield sampleRisk of obesityLogistic regression analysisCentral nervous systemGenetic variantsObesityNervous systemCommon genetic variantsAlcohol addictionCaucasian populationRegression analysisPLINK softwareGenetic associationV geneFirst evidenceAssociationCaucasian samplesGenetic componentPopulation