Amplitude of low-frequency fluctuations on Alzheimer’s disease with depression: evidence from resting-state fMRI
Mu Y, Li Y, Zhang Q, Ding Z, Wang M, Luo X, Guo X, Xu M. Amplitude of low-frequency fluctuations on Alzheimer’s disease with depression: evidence from resting-state fMRI. General Psychiatry 2020, 33: e100147. PMID: 32695958, PMCID: PMC7351268, DOI: 10.1136/gpsych-2019-100147.Peer-Reviewed Original ResearchBilateral superior frontal gyrusAlzheimer's diseaseSuperior frontal gyrusMiddle frontal gyrusFrontal gyrusInferior frontal gyrusResting-state functional magnetic resonance imagingZhejiang Provincial People's HospitalBrain functional alterationsMechanisms of ADLow-frequency fluctuationsBrain activityFunctional magnetic resonance imagingMagnetic resonance imagingResting-state fMRIALFF valuesPathophysiologic featuresPeople's HospitalInclusion criteriaDepressive symptomsFunctional alterationsPatientsResonance imagingLeft inferior frontal gyrusCore symptomsAltered brain function and clinical features in patients with first-episode, drug naïve major depressive disorder: A resting-state fMRI study
Liang S, Xue K, Wang W, Yu W, Ma X, Luo S, Zhang J, Sun X, Luo X, Liu F, Zhang Y. Altered brain function and clinical features in patients with first-episode, drug naïve major depressive disorder: A resting-state fMRI study. Psychiatry Research Neuroimaging 2020, 303: 111134. PMID: 32652482, DOI: 10.1016/j.pscychresns.2020.111134.Peer-Reviewed Original ResearchConceptsMajor depressive disorderDrug-naïve major depressive disorderAltered brain functionFunctioning Assessment Short TestMATRICS Consensus Cognitive BatteryMDD patientsDepressive disorderDefault mode networkBrain functionClinical featuresFunctional impairmentHealthy subjectsLow-frequency fluctuation (ALFF) valuesDrug-naïve MDD patientsResting-state fMRI studyAssessment Short TestTotal FAST scoresALFF valuesNeurocognitive impairmentPatientsConsensus Cognitive BatteryLingual gyrusOccupational functioningFAST scoreGlobal functioning