Xiaomei Cong, PhD, RN, FAAN
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Associate Dean of Research , Yale School of Nursing
Deputy Director (Nursing), Yale Center for Clinical Investigation (YCCI)
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Professor
Associate Dean of Research , Yale School of Nursing; Deputy Director (Nursing), Yale Center for Clinical Investigation (YCCI)
Biography
Dr. Cong received her PhD from Case Western Reserve University, MSN from Chiang Mai University, and BS from Peking University. She is a nursing researcher with longstanding clinical and research interests in symptoms science, e.g., the bio-behavioral mechanisms of pain and stress and self-management with health outcomes. In 2022, she became Associate Dean of Research at the Yale School of Nursing. She is one of the first nurse scientists investigating pain/stress and neurodevelopment in infants using multi-omic approaches. Her research addresses some of the most complex issues surrounding early life experience in high-risk infants and implementation of pain management strategies in vulnerable populations. She has over 20 years of research experience and have led many projects funded by the NIH-NINR. The impact of her research is far-reaching in biobehavioral science, symptom management, healthcare policies, and practice.
Appointments
Departments & Organizations
Education & Training
- PhD
- Case Western Reserve University (2006)
- MS
- Chiang Mai University, Maternal and Child Health (1996)
- BMedSci
- Peking University , Medicine/Nursing (1990)
Research
Overview
Public Health Interests
Breastfeeding; Clinical Trials; Genetics, Genomics, Epigenetics; Maternal & Child Health; Microbiome; Child/Adolescent Health; Health Equity, Disparities, Social Determinants and Justice; Perinatal/Prenatal Health
ORCID
0000-0002-4992-199X- View Lab Website
Lab Website
Research at a Glance
Publications Timeline
A big-picture view of Xiaomei Cong's research output by year.
122Publications
3,555Citations
Publications
2024
HPV Status and Oral Health Symptom Patterning During Treatment and Survivorship in Patients With Head and Neck Cancer: A Longitudinal Analysis.
Dunnack Yackel H, Xu W, Wun Lee J, Cong X, Salner A, Duffy V, Judge M. HPV Status and Oral Health Symptom Patterning During Treatment and Survivorship in Patients With Head and Neck Cancer: A Longitudinal Analysis. Oncology Nursing Forum 2024, 51: 565-575. PMID: 39431692, DOI: 10.1188/24.onf.565-575.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsHead and neck cancerOral health symptomsHuman papillomavirusNeck cancerHPV-negative head and neck cancersHealth symptomsHuman papillomavirus statusRetrospective longitudinal chart reviewSocial determinants of healthRegional cancer instituteDeterminants of healthLongitudinal chart reviewConcurrent chemotherapyHPV statusRadiation therapyLatent transition analysisChart reviewSymptom patternsSocial determinantsImprove outcomesCancer InstitutePatientsTime pointsEarly interventionLongitudinal analysisAssociation between mitochondrial DNA copy number and neurodevelopmental outcomes among black and white preterm infants up to two years of age
Zhao T, Li A, Reese B, Cong Q, Corwin E, Taylor S, Matson A, Chen M, Alder N, Cong X. Association between mitochondrial DNA copy number and neurodevelopmental outcomes among black and white preterm infants up to two years of age. Interdisciplinary Nursing Research 2024, 3 PMCID: PMC11567671, DOI: 10.1097/nr9.0000000000000071.Peer-Reviewed Original ResearchConceptsPreterm premature rupture of membranesNICU Network Neurobehavioral ScaleNeurodevelopmental outcomesPostmenstrual agePreterm infantsDNA copy numberMitochondrial DNA copy numberPremature rupture of membranesYears of corrected ageIncreased mtDNAcnInfants up to 1 yearBayley Scales of InfantBirth gestational ageInfant clinical characteristicsPreterm premature ruptureWhite preterm infantsRupture of membranesInfant neurobehavioral outcomesAbnormal copy numberCopy numberYears of ageGestational ageInfant outcomesNeurobehavioral ScaleClinical characteristicsNurse-led self-management support to improve symptom management and self-reported outcomes in people with irritable bowel syndrome
Barandouzi Z, Chen J, Henderson W, Starkweather A, Cong X. Nurse-led self-management support to improve symptom management and self-reported outcomes in people with irritable bowel syndrome. Interdisciplinary Nursing Research 2024, 3 PMCID: PMC11567672, DOI: 10.1097/nr9.0000000000000069.Peer-Reviewed Original ResearchConceptsSelf-management sessionsQuality of lifeSelf-management supportSelf-management interventionsRegistered nursesSelf-reported outcomesPhysical activitySelf-managementSymptom managementIrritable bowel syndromeNurse-led supportImprove symptom managementImprove self-managementImprove dietary habitsSelf-management approachParent randomized controlled trialManagement of irritable bowel syndromeRandomized controlled trialsNurse-ledHigh-fat foodsParticipants' needsIn-personDietary habitsDisorders of gut-brain interactionSymptom episodesAcceptability, Effectiveness, and Roles of mHealth Applications in Supporting Cancer Pain Self-Management: Integrative Review
Wu W, Graziano T, Salner A, Chen M, Judge M, Cong X, Xu W. Acceptability, Effectiveness, and Roles of mHealth Applications in Supporting Cancer Pain Self-Management: Integrative Review. JMIR MHealth And UHealth 2024, 12: e53652. PMID: 39024567, PMCID: PMC11294773, DOI: 10.2196/53652.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPain self-managementSelf-managementMHealth appsIntegrative reviewJohns Hopkins Research Evidence Appraisal ToolEffectiveness of mHealth appsFrequency of breakthrough painDigital technology-based interventionTechnology-based interventionsPain appCINAHL PlusNarrative synthesisAppraisal ToolMobile healthHealth outcomesMultimodal interventionMedication adherenceManaging painMeasure painMHealth applicationsMHealthInternal consistencyEducation facilitatorsSupport coordinatorsPositive experiences98 The Crosstalk between Mitochondrial Dysfunction and Neurodevelopmental Outcomes in Preterm Infants with Pain/Stress in the NICU
Zhao T, Chang X, Biswas S, Balsbaugh J, Liddle J, Chen M, Matson A, Cong X. 98 The Crosstalk between Mitochondrial Dysfunction and Neurodevelopmental Outcomes in Preterm Infants with Pain/Stress in the NICU. Journal Of Clinical And Translational Science 2024, 8: 27-27. PMCID: PMC11023861, DOI: 10.1017/cts.2024.96.Peer-Reviewed Original ResearchConceptsNICU Network Neurobehavioral ScalePreterm premature rupture of membranesPost-menstrual agePreterm infantsNeurodevelopmental outcomesNeurobehavioral outcomesAssociated with neurobehavioral outcomesNNNS summary scoresPremature rupture of membranesWeeks post-menstrual ageAssociated with neurodevelopmental outcomesPreterm premature ruptureRupture of membranesAssociated with protein levelsProspective cohort studyMitochondrial dysfunctionNICU hospitalizationNeurobehavioral ScaleClinical characteristicsPretermEpithelial barrierCohort studyReceptor binding activityNICUInfantsMulti-Omics Analysis of Gut Microbiota and Host Transcriptomics Reveal Dysregulated Immune Response and Metabolism in Young Adults with Irritable Bowel Syndrome
Chen J, Zhao T, Li H, Xu W, Maas K, Singh V, Chen M, Dorsey S, Starkweather A, Cong X. Multi-Omics Analysis of Gut Microbiota and Host Transcriptomics Reveal Dysregulated Immune Response and Metabolism in Young Adults with Irritable Bowel Syndrome. International Journal Of Molecular Sciences 2024, 25: 3514. PMID: 38542485, PMCID: PMC10970623, DOI: 10.3390/ijms25063514.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsGut microbiotaIrritable bowel syndrome subjectsHost transcriptomeIrritable bowel syndromeMetabolic pathways of gut microbiotaTranscriptome profilingAnalysis of gut microbiotaDysbiosis of gut microbiotaDysregulated immune responseRNA-seq dataHealthy controlsMulti-omics analysisImmune responseImmune system processRNA-seqGene OntologyBowel syndromeIBS participantsMulti-omicsMicrobiotaMetabolic pathwaysPathways of antigen processingPeripheral blood samplesGutStool samplesThe impact of digitalized community-based square-stepping exercise program on cognitive and balance functions among older adults living in senior facilities: a pilot study
Lee K, Boham M, Zhao M, Ro Y, Cong X, Huang Y. The impact of digitalized community-based square-stepping exercise program on cognitive and balance functions among older adults living in senior facilities: a pilot study. Interdisciplinary Nursing Research 2024, 3: 9-16. DOI: 10.1097/nr9.0000000000000053.Peer-Reviewed Original ResearchConceptsSquare-stepping exercise programExercise programOlder adultsSenior facilitiesBalance functionPreliminary effectivenessPilot studyNon-Hispanic white womenHealth promotion modelBerg Balance ScaleHomogeneity of participantsMontreal Cognitive AssessmentCognitive functionBalance ScaleFunctional mobilitySocial cognitive theoryFall riskActive lifestylePhysical functionIntervention groupQuasi-experiment designPromotion modelImprove cognitive functionWhite womenCognitive AssessmentPain/Stress, Mitochondrial Dysfunction, and Neurodevelopment in Preterm Infants
Zhao T, Chang X, Biswas S, Balsbaugh J, Liddle J, Chen M, Matson A, Alder N, Cong X. Pain/Stress, Mitochondrial Dysfunction, and Neurodevelopment in Preterm Infants. Developmental Neuroscience 2024, 46: 341-352. PMID: 38286121, PMCID: PMC11284246, DOI: 10.1159/000536509.Peer-Reviewed Original ResearchCitationsAltmetricConceptsNeonatal intensive care unitPreterm premature rupture of membranesNICU Network Neurobehavioral ScalePost-menstrual ageNeurodevelopmental outcomesPreterm infantsNeurobehavioral outcomesNeonatal Intensive Care Unit Network Neurobehavioral ScaleNeonatal intensive care unit hospitalizationPremature rupture of membranesWeeks post-menstrual agePreterm premature ruptureRupture of membranesAssociated with neurobehavioral outcomesAssociated with protein levelsAdverse neurodevelopmental outcomesBuccal swabsOptimal neurodevelopmental outcomesProspective cohort studyIntensive care unitEvaluate protein expression levelsNeurobehavioral ScaleClinical characteristicsPretermMitochondrial function-related proteins
2023
DIFFERENTIAL PAIN SENSATION AND GUT MICROBIOME BETWEEN YOUNG AND OLDER ADULTS
Chen J, Wang Z, Starkweather A, Chen M, Miao H, Ahn H, Cong X. DIFFERENTIAL PAIN SENSATION AND GUT MICROBIOME BETWEEN YOUNG AND OLDER ADULTS. Innovation In Aging 2023, 7: 800-800. PMCID: PMC10737760, DOI: 10.1093/geroni/igad104.2582.Peer-Reviewed Original ResearchConceptsCold pain thresholdHeat pain thresholdCold detection thresholdGut microbiota profilePressure pain thresholdPain thresholdShannon indexMicrobiota profilesChao indexBeta diversity indicesLower cold pain thresholdStool samplesHigher pressure pain thresholdsQuantitative sensory testing dataYoung adultsAbundant taxaPeripheral sensationAge of young adultsGut microbiotaDiversity indexA-diversityPain sensationSpearman correlation analysisPain processingHigher speciesHealth disparities in preterm births
Brown J, Chang X, Matson A, Lainwala S, Chen M, Cong X, Casavant S. Health disparities in preterm births. Frontiers In Public Health 2023, 11: 1275776. PMID: 38162611, PMCID: PMC10757361, DOI: 10.3389/fpubh.2023.1275776.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsPreterm birth rateNeonatal intensive care unitPreterm infantsPreterm birthNon-Hispanic white (WNeonatal Infant Stressor ScaleBirth rateClinical treatment informationHealth disparitiesImprove social determinants of healthIntensive care unitSocial determinants of healthOutcome inequalityDeterminants of healthImprove social determinantsElectronic health recordsNeurodevelopmental outcomesPretermHospital stayAdverse health outcomesAnthropometric measurementsLifesaving procedureLife course approachCross-sectional analysisCare unit
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