2020
Identifying a Kidney Transplant Recipient COVID Phenotype to Aid Test Utilization in the Setting of Limited Testing Availability—Does One Exist?
Virmani S, Gleeson SE, Girone GF, Malhotra D, Cohen EA, Klarman SE, Asch WS. Identifying a Kidney Transplant Recipient COVID Phenotype to Aid Test Utilization in the Setting of Limited Testing Availability—Does One Exist? Transplantation Proceedings 2020, 52: 2584-2591. PMID: 32711848, PMCID: PMC7305913, DOI: 10.1016/j.transproceed.2020.05.033.Peer-Reviewed Original ResearchConceptsKidney transplant recipientsSARS-CoV-2BK viremiaLimited testing availabilityTesting availabilitySevere acute respiratory syndrome 2 virusImmunosuppressed kidney transplant recipientsOutpatient testing centerPolyoma BK viremiaCOVID-19 infectionPositive predictive valueTransplant recipientsImmunocompetent patientsSymptomatic patientsImmunosuppressed patientsTransplant centersHigh morbidityEmergency departmentInpatient treatmentGeneral populationHigh incidencePatientsCenter deliveriesPredictive valueTest utilization
2017
Delayed Graft Function Phenotypes and 12-Month Kidney Transplant Outcomes
Hall IE, Reese PP, Doshi MD, Weng FL, Schröppel B, Asch WS, Ficek J, Thiessen-Philbrook H, Parikh CR. Delayed Graft Function Phenotypes and 12-Month Kidney Transplant Outcomes. Transplantation 2017, 101: 1913-1923. PMID: 27495761, PMCID: PMC5292094, DOI: 10.1097/tp.0000000000001409.Peer-Reviewed Original ResearchConceptsIschemia-reperfusion injurySlow graft functionDelayed graft functionKidney transplant outcomesGraft functionTransplant outcomesCreatinine reductionDeath-censored graft failureDeceased donor kidney recipientsPoor kidney transplant outcomesSevere ischemia-reperfusion injuryGlomerular filtration rateLong-term outcomesLarger translational studiesDGF definitionsIRI severityKidney recipientsDialysis initiationGraft failureProspective studyUnited NetworkFiltration rateRelative riskDialysis sessionOrgan Sharing
2016
Belatacept and Eculizumab for Treatment of Calcineurin Inhibitor-induced Thrombotic Microangiopathy After Kidney Transplantation: Case Report
Merola J, Yoo PS, Schaub J, Smith JD, Rodriguez-Davalos MI, Tichy E, Mulligan DC, Asch W, Formica R, Kashgarian M, Kulkarni S. Belatacept and Eculizumab for Treatment of Calcineurin Inhibitor-induced Thrombotic Microangiopathy After Kidney Transplantation: Case Report. Transplantation Proceedings 2016, 48: 3106-3108. PMID: 27932157, DOI: 10.1016/j.transproceed.2016.04.005.Peer-Reviewed Original ResearchConceptsCalcineurin inhibitorsHemolytic uremic syndromeThrombotic microangiopathyKidney transplantationUremic syndromeMinimization of CNIsAtypical hemolytic uremic syndromeWithdrawal of tacrolimusEarly graft lossFavorable clinical courseGraft dysfunctionGraft lossImmunosuppression strategiesUsual therapyClinical courseCase reportCTLA-4Endothelial reactionFrequent causeChallenging causeUncontrolled activationMonoclonal antibodiesCellular destructionMicroangiopathyComponent C5
2015
Duration of Prophylaxis against Fungal Infection in Kidney Transplant Recipients
Guerra CM, Formica RN, Kulkarni S, Asch WS, Tichy EM. Duration of Prophylaxis against Fungal Infection in Kidney Transplant Recipients. Progress In Transplantation 2015, 25: 311-315. PMID: 26645924, DOI: 10.7182/pit2015929.Peer-Reviewed Original ResearchConceptsKidney transplant recipientsTransplant recipientsDuration of admissionCandida esophagitisFungal infectionsAdult kidney transplant recipientsEpisodes of thrushDuration of prophylaxisRetrospective chart reviewPrimary outcome measureFisher's exact testAdministration of nystatinStudent's t-testChart reviewOutcome measuresExact testEsophagitisProphylaxisRecipientsInfectionProtocol changesT-testAdmissionTransplantP-value
2012
A One-Day Centralized Work-up for Kidney Transplant Recipient Candidates: A Quality Improvement Report
Formica RN, Barrantes F, Asch WS, Bia MJ, Coca S, Kalyesubula R, McCloskey B, Leary T, Arvelakis A, Kulkarni S. A One-Day Centralized Work-up for Kidney Transplant Recipient Candidates: A Quality Improvement Report. American Journal Of Kidney Diseases 2012, 60: 288-294. PMID: 22571868, DOI: 10.1053/j.ajkd.2012.04.008.Peer-Reviewed Original ResearchConceptsKidney transplantImprovement reportMultivariable Cox proportional hazards modelsCox proportional hazards modelKidney transplant candidacyMinimal listing criteriaGroup of patientsUniversity-based hospitalQuality improvement reportProportional hazards modelTransplant candidacyTransplant evaluationUNOS waitlistWaitlist placementTransplant centersComorbid conditionsMedian timeMultivariable analysisTransplant practitionersDialysis exposureFunctional statusWait listHazards modelPatientsRecipient candidatesPatient Education to Reduce Disparities in Renal Transplantation
Asch WS, Bia MJ. Patient Education to Reduce Disparities in Renal Transplantation. Clinical Journal Of The American Society Of Nephrology 2012, 7: 527-529. PMID: 22403275, DOI: 10.2215/cjn.01770212.Commentaries, Editorials and Letters
2011
Should Living Kidney Donor Candidates with Impaired Fasting Glucose Donate?
Vigneault CB, Asch WS, Dahl NK, Bia MJ. Should Living Kidney Donor Candidates with Impaired Fasting Glucose Donate? Clinical Journal Of The American Society Of Nephrology 2011, 6: 2054-2059. PMID: 21784837, DOI: 10.2215/cjn.03370411.BooksConceptsTransplant centersLiving donorsDonor candidatesGreater riskImpaired glucose toleranceImpaired glucose metabolismDefinition of diabetesPotential living donorsKidney donor candidatesFuture diabetesKidney transplantMetabolic syndromeGlucose toleranceKidney donorsDonor screeningTransplant guidelinesHispanic ethnicityGlucose metabolismDiabetesHispanic individualsPotential donorsIFGRiskDonorsEthnicity
1998
Restricted expression of the neuronal intermediate filament protein plasticin during zebrafish development
Canger A, Passini M, Asch W, Leake D, Zafonte B, Glasgow E, Schechter N. Restricted expression of the neuronal intermediate filament protein plasticin during zebrafish development. The Journal Of Comparative Neurology 1998, 399: 561-572. PMID: 9741483, DOI: 10.1002/(sici)1096-9861(19981005)399:4<561::aid-cne8>3.0.co;2-#.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodiesAxonsBlotting, WesternCytoskeletonDNA, ComplementaryEye ProteinsFemaleGene Expression Regulation, DevelopmentalGoldfishIntermediate Filament ProteinsLarvaMaleMembrane GlycoproteinsNerve Tissue ProteinsNeurofilament ProteinsNeuronsOptic NervePeripherinsRNA, MessengerZebrafishZebrafish ProteinsConceptsRetinal ganglion cellsNervous systemOptic nerve injuryPeripheral nervous systemNerve injuryGanglion neuronsProjection neuronsRGC axonsReticulospinal neuronsGanglion cellsCranial nervesProject axonsAxon regenerationEarly neuronsVisual pathwayLong axonsAxonal outgrowthNeuronsNeuronal developmentAxon tractsRohon-BeardAxonsEarly stagesAxon outgrowthRestricted expressionCloning of zebrafish vsx1: Expression of a paired‐like homeobox gene during CNS development
Passini M, Kurtzman A, Canger A, Asch W, Wray G, Raymond P, Schechter N. Cloning of zebrafish vsx1: Expression of a paired‐like homeobox gene during CNS development. Genesis 1998, 23: 128-141. PMID: 9770270, DOI: 10.1002/(sici)1520-6408(1998)23:2<128::aid-dvg5>3.0.co;2-8.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceCentral Nervous SystemCloning, MolecularEmbryo, NonmammalianEye ProteinsFemaleFish ProteinsGene Expression Regulation, DevelopmentalGenesGenes, HomeoboxGoldfishHomeodomain ProteinsIn Situ HybridizationMaleMolecular Sequence DataOptic NerveRegulatory Sequences, Nucleic AcidRetinaRNA, MessengerSequence AlignmentSequence Homology, Amino AcidZebrafishZebrafish ProteinsConceptsInner nuclear layerSpinal cord neuronsRetina of zebrafishCord neuronsRetinal interneuronsSpinal cordExpression patternsNuclear layerRetinal expressionCombined expression patternCVC domainRetinaCNS developmentRetinal libraryPaired-like homeobox geneVSX1Vsx1 expressionDevelopmental expressionChx10ExpressionHomeobox genesSpatiotemporal expression patternsRelated genesPaired-type homeodomainLower vertebrates