2019
A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders
Rayner C, Coleman JRI, Purves KL, Hodsoll J, Goldsmith K, Alpers GW, Andersson E, Arolt V, Boberg J, Bögels S, Creswell C, Cooper P, Curtis C, Deckert J, Domschke K, El Alaoui S, Fehm L, Fydrich T, Gerlach AL, Grocholewski A, Hahlweg K, Hamm A, Hedman E, Heiervang ER, Hudson JL, Jöhren P, Keers R, Kircher T, Lang T, Lavebratt C, Lee SH, Lester KJ, Lindefors N, Margraf J, Nauta M, Pané-Farré CA, Pauli P, Rapee RM, Reif A, Rief W, Roberts S, Schalling M, Schneider S, Silverman WK, Ströhle A, Teismann T, Thastum M, Wannemüller A, Weber H, Wittchen HU, Wolf C, Rück C, Breen G, Eley TC. A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders. Translational Psychiatry 2019, 9: 150. PMID: 31123309, PMCID: PMC6533285, DOI: 10.1038/s41398-019-0481-y.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyBehavioral therapyAnxiety disordersTherapy outcomeEvidence-based treatmentsPolygenic scoringMajor depressive disorderGenome-wide association studiesDepressive disorderGenome-wide associationStrong genetic correlationCommon genetic variantsComplex traitsSingle nucleotide polymorphismsWide associationStrongest predictorPsychopathologyAnxietyPersonalityGenetic overlapAssociation studiesGenetic correlationsGenetic variantsNucleotide polymorphismsDisorders
2015
Anxiety sensitivity moderates behavioral avoidance in anxious youth
Lebowitz ER, Shic F, Campbell D, Basile K, Silverman WK. Anxiety sensitivity moderates behavioral avoidance in anxious youth. Behaviour Research And Therapy 2015, 74: 11-17. PMID: 26348546, PMCID: PMC4895193, DOI: 10.1016/j.brat.2015.08.009.Peer-Reviewed Original ResearchConceptsAnxiety sensitivityFear of spidersSensations of anxietyBehavioral avoidanceSpider stimuliAnxious youthRole of ASAvoidant behaviorAnxiety treatmentOverall avoidanceAnxietyStimuliYouthFearStrongest predictorAvoidancePatient's abilityIndividualsSensationModeratesAbilityImplicationsPredictorsSupportBehavior
2001
Cognitive Errors in Youth with Anxiety Disorders: The Linkages Between Negative Cognitive Errors and Anxious Symptoms
Weems C, Berman S, Silverman W, Saavedra L. Cognitive Errors in Youth with Anxiety Disorders: The Linkages Between Negative Cognitive Errors and Anxious Symptoms. Cognitive Therapy And Research 2001, 25: 559-575. DOI: 10.1023/a:1005505531527.Peer-Reviewed Original ResearchNegative cognitive errorsCognitive errorsAnxiety sensitivityTrait anxietyChildren's Negative Cognitive Error QuestionnaireManifest anxietyChildren's levelSelective abstractionCognitive Error QuestionnaireStrongest predictorSelf-report measuresMeasures of anxietySample of childrenPotential treatment implicationsCognitive modelAnxiety problemsAnxiety disordersAnxious symptomsTreatment implicationsFuture research directionsAnxietyOvergeneralizationStepwise regression analysisYouthDepression